Search Results - "Ismael Olmos"

An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels by de Leon, Jose, Schoretsanitis, Georgios, Smith, Robert L, Molden, Espen, Solismaa, Anssi, Seppälä, Niko, Kopeček, Miloslav, Švancer, Patrik, Olmos, Ismael, Ricciardi, Carina, Iglesias-Garcia, Celso, Iglesias-Alonso, Ana, Spina, Edoardo, Ruan, Can-Jun, Wang, Chuan-Yue, Wang, Gang, Tang, Yi-Lang, Lin, Shih-Ku, Lane, Hsien-Yuan, Kim, Yong Sik, Kim, Se Hyun, Rajkumar, Anto P, González-Esquivel, Dinora F, Jung-Cook, Helgi, Baptista, Trino, Rohde, Christopher, Nielsen, Jimmi, Verdoux, Hélène, Quiles, Clelia, Sanz, Emilio J, De Las Cuevas, Carlos, Cohen, Dan, Schulte, Peter F J, Ertuğrul, Aygün, Anıl Yağcıoğlu, A Elif, Chopra, Nitin, McCollum, Betsy, Shelton, Charles, Cotes, Robert O, Kaithi, Arun R, Kane, John M, Farooq, Saeed, Ng, Chee H, Bilbily, John, Hiemke, Christoph, López-Jaramillo, Carlos, McGrane, Ian, Lana, Fernando, Eap, Chin B, Arrojo-Romero, Manuel, Rădulescu, Flavian Ş, Seifritz, Erich, Every-Palmer, Susanna, Bousman, Chad A, Bebawi, Emmanuel, Bhattacharya, Rahul, Kelly, Deanna L, Otsuka, Yuji, Lazary, Judit, Torres, Rafael, Yecora, Agustin, Motuca, Mariano, Chan, Sherry K W, Zolezzi, Monica, Ouanes, Sami, De Berardis, Domenico, Grover, Sandeep, Procyshyn, Ric M, Adebayo, Richard A, Kirilochev, Oleg O, Soloviev, Andrey, Fountoulakis, Konstantinos N, Wilkowska, Alina, Cubała, Wiesław J, Ayub, Muhammad, Silva, Alzira, Bonelli, Raphael M, Villagrán-Moreno, José M, Crespo-Facorro, Benedicto, Temmingh, Henk, Decloedt, Eric, Pedro, Maria R, Takeuchi, Hiroyoshi, Tsukahara, Masaru, Gründer, Gerhard, Sagud, Marina, Celofiga, Andreja, Ignjatovic Ristic, Dragana, Ortiz, Bruno B, Elkis, Helio, Pacheco Palha, António J, LLerena, Adrián, Fernandez-Egea, Emilio, Siskind, Dan, Weizman, Abraham, Masmoudi, Rim, Mohd Saffian, Shamin, Leung, Jonathan G, Buckley, Peter F, Marder, Stephen R

“…This international guideline proposes improving clozapine package inserts worldwide by using ancestry-based dosing and titration. Adverse drug reaction (ADR)…”
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Clozapine safety monitoring and related research in psychiatry and neurology in South America: A scoping review by Baptista, Trino, Serrano, Ana, Presti, Alirio Perez Lo, Fernandez-Arana, Alberto, Elkis, Helio, Motuca, Mariano, Olmos, Ismael, Schoretsanitis, Georgios

“…The quality and quantity of clozapine safety monitoring considerably differs among South American countries and mainly focus on hematological surveillance. Few…”
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Population Pharmacokinetics of Clozapine and Norclozapine and Switchability Assessment between Brands in Uruguayan Patients with Schizophrenia by Fagiolino, Pietro, Maldonado, Cecilia, Vázquez, Marta, Ibarra, Manuel, Olmos, Ismael, Giachetto, G.

“…Clozapine (CZP) is an atypical antipsychotic agent commonly used in the treatment of schizophrenia. It is metabolized primarily by CYP1A2 enzyme, yielding a…”
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Tasas de suicidio y concentración de litio en agua corriente en Rocha y Montevideo: Primer estudio en Uruguay, período 2019-2020 by Frontini, María Alcira, Olmos, Ismael, Giraldez, Gonzalo, Lara, Fabián

“…El suicidio es un fenómeno que además de las pérdidas humanas que involucra, repercute negativamente en familiares y allegados, produciendo a su vez enormes…”
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Optimization of Clozapine Treatment: Study of Variables Affecting Response in Uruguayan Patients With Schizophrenia by Olmos, Ismael, Ricciardi, Carina, Mato, Mauricio, Guevara, Natalia, Acuña, Sabrina, Maldonado, Cecilia, Vázquez, Marta, Toledo, Mauricio, Menéndez, Clara, Blanco, Valentina, Badano, José L., Cayota, Alfonso, Spangenberg, Lucia, Cardenas-Rodriguez, Magdalena

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European Whites May Need Lower Minimum Therapeutic Clozapine Doses Than Those Customarily Proposed by Schoretsanitis, Georgios, Smith, Robert L., Molden, Espen, Solismaa, Anssi, Seppälä, Niko, Kopeček, Miloslav, Švancer, Patrik, Olmos, Ismael, Vázquez, Marta, Iglesias-Garcia, Celso, Iglesias-Alonso, Ana, Spina, Edoardo, de Leon, Jose

“…A nomogram from a British naturalistic study proposed that the clozapine dosing needed to reach a serum concentration of 350 ng/mL ranged from 265 mg/d (female…”
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An expert review of clozapine in Latin American countries: Use, monitoring, and pharmacovigilance by Baptista, Trino, Motuca, Mariano, Serrano, Ana, Perez Lo Presti, Alirio, Fernandez-Arana, Alberto, Olmos, Ismael, Pabon, Albis, Yepez, Juan Genaro Ayala, Alejo Galarza, Gabriel de Jesus, Rivera Ramirez, Nuria Monserrat, Elkis, Helio, Sanz, Emilio J., De Las Cuevas, Carlos, de Leon, Jose

“…There is growing interest in clozapine clinical use, monitoring, and research, particularly adverse drug reactions (ADRs) other than agranulocytosis. In this…”
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Exploring low clozapine C/D ratios, inverted clozapine-norclozapine ratios and undetectable concentrations as measures of non-adherence in clozapine patients: A literature review and a case series of 17 patients from 3 studies by Ruan, Can-Jun, Olmos, Ismael, Ricciardi, Carina, Schoretsanitis, Georgios, Vincent, Philippe D, Anıl Yağcıoğlu, A Elif, Eap, Chin B, Baptista, Trino, Clark, Scott R, Fernandez-Egea, Emilio, Kim, Se Hyun, Lane, Hsien-Yuan, Leung, Jonathan, Maroñas Amigo, Olalla, Motuca, Mariano, Every-Palmer, Susanna, Procyshyn, Ric M, Rohde, Christopher, Suhas, Satish, Schulte, Peter F J, Spina, Edoardo, Takeuchi, Hiroyoshi, Verdoux, Hélène, Correll, Christoph U, Molden, Espen, De Las Cuevas, Carlos, de Leon, Jose

“…Up to 1/2 of outpatients prescribed clozapine may be partially/fully non-adherent, based on therapeutic drug monitoring (TDM). Three indices for measuring…”
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Clozapine ultrarapid metabolism during weak induction probably exists but requires careful diagnosis. A literature review, five new cases and a proposed definition by Schoretsanitis, Georgios, Anıl Yağcıoğlu, A. Elif, Ruan, Can-Jun, Eap, Chin B., Molden, Espen, Baptista, Trino, Clark, Scott R., Fernandez-Egea, Emilio, Kim, Se Hyun, Lane, Hsien-Yuan, Leung, Jonathan, Maroñas Amigo, Olalla, Motuca, Mariano, Olmos, Ismael, Every-Palmer, Susanna, Procyshyn, Ric M., Rohde, Christopher, Satish, Suhas, Schulte, Peter F.J., Spina, Edoardo, Takeuchi, Hiroyoshi, Verdoux, Hélène, Correll, Christoph U., de Leon, Jose

“…During weak induction (from smoking and/or valproate co-prescription), clozapine ultrarapid metabolizers (UMs) need very high daily doses to reach the minimum…”
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Exploring low clozapine C/D ratios, inverted clozapine-norclozapine ratios and undetectable concentrations as measures of non-adherence in clozapine patients by Ruan, Can-Jun, Olmos, Ismael, Ricciardi, Carina, Schoretsanitis, Georgios, Vincent, Philippe D., Anıl Yağcıoğlu, A. Elif, Eap, Chin B., Baptista, Trino, Clark, Scott R., Fernandez-Egea, Emilio, Kim, Se Hyun, Lane, Hsien-Yuan, Leung, Jonathan, Maroñas Amigo, Olalla, Motuca, Mariano, Every-Palmer, Susanna, Procyshyn, Ric M., Rohde, Christopher, Suhas, Satish, Schulte, Peter F.J., Spina, Edoardo, Takeuchi, Hiroyoshi, Verdoux, Hélène, Correll, Christoph U., Molden, Espen, De Las Cuevas, Carlos, de Leon, Jose

“…Up to 1/2 of outpatients prescribed clozapine may be partially/fully non-adherent, based on therapeutic drug monitoring (TDM). Three indices for measuring…”
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Escaping the Long Shadow Cast by Agranulocytosis: Reflections on Clozapine Pharmacovigilance Focused on the United Kingdom by de Leon, Jose, Arrojo-Romero, Manuel, Verdoux, Hélène, Ruan, Can-Jun, Schoretsanitis, Georgios, Rohde, Christopher, Cohen, Dan, Schulte, Peter F.J., Kim, Se Hyun, Cotes, Robert O., Leung, Jonathan G., Otsuka, Yuji, Kirilochev, Oleg O., Baptista, Trino, Grover, Sandeep, Every-Palmer, Susanna, Clark, Scott R., McGrane, Ian R., Motuca, Mariano, Olmos, Ismael, Wilkowska, Alina, Sagud, Marina, Anil Yağcioğlu, A. Elif, Ristic, Dragana Ignjatovic, Lazary, Judit, Sanz, Emilio J., De Las Cuevas, Carlos

“…A recent article in this journal presented a US perspective regarding the modernization of clozapine prescription and proposed an escape from the long shadow…”
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Escaping the Long Shadow Cast by Agranulocytosis: Reflections on Clozapine Pharmacovigilance Focused on the United Kingdom by de Leon, Jose, Arrojo-Romero, Manuel, Verdoux, Hélène, Ruan, Can-Jun, Schoretsanitis, Georgios, Rohde, Christopher, Cohen, Dan, Schulte, Peter F.J., Kim, Se Hyun, Cotes, Robert O., Leung, Jonathan G., Otsuka, Yuji, Kirilochev, Oleg O., Baptista, Trino, Grover, Sandeep, Every-Palmer, Susanna, Clark, Scott R., McGrane, Ian R., Motuca, Mariano, Olmos, Ismael, Wilkowska, Alina, Sagud, Marina, Anıl Yağcıoğlu, A. Elif, Ristic, Dragana Ignjatovic, Lazary, Judit, Sanz, Emilio J., De Las Cuevas, Carlos

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European Whites May Need Lower Minimum Therapeutic Clozapine Doses Than Those Customarily Proposed by Schoretsanitis, Georgios, Smith, Robert L., Molden, Espen, Solismaa, Anssi, Seppälä, Niko, Kopeček, Miloslav, Švancer, Patrik, Olmos, Ismael, Vázquez, Marta, Iglesias-Garcia, Celso, Iglesias-Alonso, Ana, Spina, Edoardo, de Leon, Jose

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Hyperammonemia Associated with Valproic Acid Concentrations by Magallanes, Laura, Olano, Ivette, Vázquez, Marta, Guevara, Natalia, Alvariza, Silvana, Ibarra, Manuel, Fagiolino, Pietro, Maldonado, Cecilia, Olmos, Ismael

“…Valproic acid, a branched short-chain fatty acid, has numerous action mechanisms which turn it into a broad spectrum anticonvulsant drug and make its use…”
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Data sources for drug utilization research in Latin American countries—A cross‐national study: DASDUR‐LATAM study by Lopes, Luciane C., Salas, Maribel, Osorio‐de‐Castro, Claudia Garcia Serpa, Leal, Lisiane Freitas, Doubova, Svetlana V., Cañás, Martín, Dreser, Anahi, Acosta, Angela, Baldoni, Andre Oliveira, Bergamaschi, Cristiane, Mota, Daniel Marques, Gómez‐Galicia, Diana L., Sepúlveda‐Viveros, Dino, Delgado, Edgard Narvaez, Lima, Elisangela, Chandia, Felipe Vera, Ferre, Felipe, Marin, Gustavo H., Olmos, Ismael, Zimmermann, Ivan R., Fulone, Izabela, Roldán‐Saelzer, Juan, Sánchez‐Salgado, Juan Carlos, Castro‐Pastrana, Lucila I., Souza, Luiz Jupiter Carneiro, Beltrán, Manuel Machado, Silva, Marcus Tolentino, Mena, María Belén, França Fonteles, Marta Maria, Urtasun, Martín A., Tarapués, Mónica, Hernández, Patricia Granja, Medero, Natalia, Herrera‐Comoglio, Raquel, Barberato‐Filho, Silvio, Galvão, Taís Freire, Luiza, Vera Lucia, Santa‐Ana‐Tellez, Yared, Rodríguez ‐ Tanta, Yesenia, Elseviers, Monique

“…Purpose Drug utilization research (DUR) contributes to inform policymaking and to strengthen health systems. The availability of data sources is the first step…”
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Consumo de benzodiazepinas en la población uruguaya by Noelia Speranza, Viviana Domínguez, Emiliano Pagano, Pía Artagaveytia, Ismael Olmos, Mauricio Toledo, Gustavo Tamosiunas

“…Objetivo: conocer el consumo de benzodiazepinas en Uruguay entre 2010 y 2012.  Material y método: se realizó un estudio de utilización de medicamentos para…”
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Impacto de la protocolización de la profilaxis antibiótica en la cesárea en el centro Hospitalario Pereira Rossell by Silvia Kegel, Noelia Speranza, Héctor Telechea, Ismael Olmos, Ana Greczanik, Gustavo Giachetto, Luciana Nanni

“…Introducción: en julio de 2002, en el Centro Hospitalario Pereira Rossell (CHPR) se implementó una pauta de profilaxis antibiótica en la cesárea que consiste…”
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Uso racional de medicamentos by Gustavo Giachetto, Patricia Banchero, Héctor Telechea, Noelia Speranza, Mijal Wolaj, Mauricio Toledo, Ismael Olmos, Gabriela Camacho, Silvia Kegel, Luciana Nanni, Carolina Seade

“…Introducción: El uso irracional de los medicamentos constituye un riesgo inadmisible para los pacientes y un continuo derroche de recursos. De los diversos…”
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