Search Results - "Islamov, Rustem R."
-
1
Induction of Angiogenesis by Genetically Modified Human Umbilical Cord Blood Mononuclear Cells
Published in International journal of molecular sciences (23-02-2023)“…Stimulating the process of angiogenesis in treating ischemia-related diseases is an urgent task for modern medicine, which can be achieved through the use of…”
Get full text
Journal Article -
2
A Biosafety Study of Human Umbilical Cord Blood Mononuclear Cells Transduced with Adenoviral Vector Carrying Human Vascular Endothelial Growth Factor cDNA In Vitro
Published in Biomedicines (01-07-2023)“…The biosafety of gene therapy remains a crucial issue for both the direct and cell-mediated delivery of recombinant cDNA encoding biologically active molecules…”
Get full text
Journal Article -
3
Spinal Cord Molecular and Cellular Changes Induced by Adenoviral Vector- and Cell-Mediated Triple Gene Therapy after Severe Contusion
Published in Frontiers in pharmacology (13-11-2017)“…The gene therapy has been successful in treatment of spinal cord injury (SCI) in several animal models, although it still remains unavailable for clinical…”
Get full text
Journal Article -
4
Triple-Gene Therapy for Stroke: A Proof-of-Concept in Vivo Study in Rats
Published in Frontiers in pharmacology (15-02-2018)“…Natural brain repair after stroke is extremely limited, and current therapeutic options are even more scarce with no clinical break-through in sight. Despite…”
Get full text
Journal Article -
5
Influence of Recombinant Codon-Optimized Plasmid DNA Encoding VEGF and FGF2 on Co-Induction of Angiogenesis
Published in Cells (Basel, Switzerland) (18-02-2021)“…Several methods for the stimulation of skin wound repair have been proposed over the last few decades. The most promising among them are gene and stem cell…”
Get full text
Journal Article -
6
Gene-modified leucoconcentrate for personalized ex vivo gene therapy in a mini pig model of moderate spinal cord injury
Published in Neural regeneration research (01-02-2021)“…We previously demonstrated that gene-modified umbilical cord blood mononuclear cells overexpressing a combination of recombinant neurotrophic factors are a…”
Get full text
Journal Article -
7
RNAi pathway is functional in peripheral nerve axons
Published in The FASEB journal (01-03-2007)“…Recent observations demonstrated that translation of mRNAs may occur in axonal processes at sites that are long distances away from the neuronal perikaria…”
Get full text
Journal Article -
8
RNA interference and amyotrophic lateral sclerosis
Published in Current drug metabolism (01-09-2011)“…Amyotrophic lateral sclerosis (ALS) is a debilitating neuro-degenerative disorder characterized by progressive loss of motor neurons. The etiology and…”
Get more information
Journal Article -
9
Over-expression of Oct4 and Sox2 transcription factors enhances differentiation of human umbilical cord blood cells in vivo
Published in Biochemical and biophysical research communications (05-09-2014)“…•Gene and cell-based therapies comprise innovative aspects of regenerative medicine.•Genetically modified hUCB-MCs enhanced differentiation of cells in a mouse…”
Get full text
Journal Article -
10
Genetically modified human umbilical cord blood cells expressing vascular endothelial growth factor and fibroblast growth factor 2 differentiate into glial cells after transplantation into amyotrophic lateral sclerosis transgenic mice
Published in Experimental biology and medicine (Maywood, N.J.) (01-01-2011)“…Current therapy of a number of neuropsychiatric maladies has only symptomatic modality. Effective treatment of these neuro-degenerative diseases, including…”
Get more information
Journal Article -
11
Bone Stress-Strain State Evaluation Using CT Based FEM
Published in Frontiers in mechanical engineering (18-06-2021)“…Nowadays, the use of a digital prototype in numerical modeling is one of the main approaches to calculating the elements of an inhomogeneous structure under…”
Get full text
Journal Article -
12
Potential role of dental stem cells in the cellular therapy of cerebral ischemia
Published in Current pharmaceutical design (01-11-2009)“…Stem cell based therapies for cerebral ischemia (CI) utilize different cell sources including embryonic stem cells (ESCs), neural stem cells (NSCs), umbilical…”
Get more information
Journal Article -
13
Human umbilical cord blood cells transfected with VEGF and L1CAM do not differentiate into neurons but transform into vascular endothelial cells and secrete neuro-trophic factors to support neuro-genesis : a novel approach in stem cell therapy
Published in Neurochemistry international (01-12-2008)Get full text
Journal Article -
14
Human umbilical cord blood cells transfected with VEGF and L(1)CAM do not differentiate into neurons but transform into vascular endothelial cells and secrete neuro-trophic factors to support neuro-genesis-a novel approach in stem cell therapy
Published in Neurochemistry international (01-12-2008)“…Genetically modified mono-nuclear cell fraction from human umbilical cord blood (HUCB) expressing human vascular endothelial growth factor (VEGF) and mouse…”
Get full text
Journal Article -
15
Retrogradely transported siRNA silences human mutant SOD1 in spinal cord motor neurons
Published in Experimental brain research (01-05-2009)“…The transgenic mouse model of familial amyotrophic lateral sclerosis (ALS) expressing human mutant ( G 93 A ) copper/zinc superoxide dismutase (SOD 1 ) is an…”
Get full text
Journal Article -
16
Induction of VEGF and its Flt-I receptor after sciatic nerve crush injury
Published in Neuroreport (01-09-2004)Get full text
Journal Article -
17
17β-Estradiol stimulates regeneration of sciatic nerve in female mice
Published in Brain research (12-07-2002)“…In ovariectomized mice with and without estrogen replacement, regeneration of the sciatic nerve after crush injury was studied. Functional recovery, quantified…”
Get full text
Journal Article -
18
Induction of VEGF and its Flt-1 receptor after sciatic nerve crush injury
Published in Neuroreport (15-09-2004)“…Expression of vascular endothelial growth factor and its receptors Flt-1 and Flk-1 was studied in lumbar spinal cord after sciatic nerve crush injury…”
Get full text
Journal Article -
19
Modulation of neurotransmitter release by carbon monoxide at the frog neuro-muscular junction
Published in Current drug metabolism (01-02-2007)“…Carbon monoxide (CO) is an endogenous gaseous messenger, which regulates numerous physiological functions in a wide variety of tissues. Using extracellular…”
Get more information
Journal Article -
20
Effect of 17β-estradiol on gene expression in lumbar spinal cord following sciatic nerve crush injury in ovariectomized mice
Published in Brain research (14-03-2003)“…Previously, we observed that estrogen treatment enhances regeneration of the sciatic nerve after crush injury [Brain Res. 943 (2002) 283]. In this research, we…”
Get full text
Journal Article