Search Results - "Islam, Sadia T."
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Modulating glutathione thiol status alters pancreatic β-cell morphogenesis in the developing zebrafish (Danio rerio) embryo
Published in Redox biology (01-01-2021)“…Emerging evidence suggests that redox-active chemicals perturb pancreatic islet development. To better understand potential mechanisms for this, we used…”
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Nonmuscle Myosin IIA Regulates the Precise Alignment of Hexagonal Eye Lens Epithelial Cells During Fiber Cell Formation and Differentiation
Published in Investigative ophthalmology & visual science (18-04-2023)“…Epithelial cells in the equatorial region of the ocular lens undergo a remarkable transition from randomly packed cells into precisely aligned and…”
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Disease-related non-muscle myosin IIA D1424N rod domain mutation, but not R702C motor domain mutation, disrupts mouse ocular lens fiber cell alignment and hexagonal packing
Published in Cytoskeleton (Hoboken, N.J.) (22-03-2024)“…The mouse ocular lens is an excellent vertebrate model system for studying hexagonal cell packing and shape changes during tissue morphogenesis and…”
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Whole Mount Imaging to Visualize and Quantify Peripheral Lens Structure, Cell Morphology, and Organization
Published in Journal of visualized experiments (19-01-2024)“…The ocular lens is a transparent flexible tissue that alters its shape to focus light from different distances onto the retina. Aside from a basement membrane…”
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Environmental determinants of type 1 diabetes: A role for overweight and insulin resistance
Published in Journal of paediatrics and child health (01-11-2014)“…Rates of type 1 diabetes are rising globally, with a decreasing proportion of high‐risk genotypes and twin concordance rates below 50%. Therefore,…”
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