Search Results - "Islam, Epshita"

Reverse vaccinology-based identification of a novel surface lipoprotein that is an effective vaccine antigen against bovine infections caused by Pasteurella multocida by Islam, Epshita A, Fegan, Jamie E, Tefera, Takele A, Curran, David M, Waeckerlin, Regula C, Ng, Dixon, Ahn, Sang Kyun, Lai, Chun Heng Royce, Nguyen, Quynh Huong, Shah, Megha, Tesfaw, Liyuwork, Adamu, Kassaye, Medhin, Wubet W, Legesse, Abinet, Deresse, Getaw, Getachew, Belayneh, Rawlyk, Neil, Evans, Brock, Potter, Andrew, Schryvers, Anthony B, Gray-Owen, Scott D, Moraes, Trevor F

“…Pasteurella multocida can infect a multitude of wild and domesticated animals, with infections in cattle resulting in hemorrhagic septicemia (HS) or…”
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A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii by Bateman, Thomas J., Shah, Megha, Ho, Timothy Pham, Shin, Hyejin Esther, Pan, Chuxi, Harris, Greg, Fegan, Jamie E., Islam, Epshita A., Ahn, Sang Kyun, Hooda, Yogesh, Gray-Owen, Scott D., Chen, Wangxue, Moraes, Trevor F.

“…Nutrient acquisition systems are often crucial for pathogen growth and survival during infection, and represent attractive therapeutic targets. Here, we study…”
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Global analysis of neutrophil responses to Neisseria gonorrhoeae reveals a self-propagating inflammatory program by Sintsova, Anna, Sarantis, Helen, Islam, Epshita A, Sun, Chun Xiang, Amin, Mohsen, Chan, Carlos H F, Stanners, Clifford P, Glogauer, Michael, Gray-Owen, Scott D

“…An overwhelming neutrophil-driven response causes both acute symptoms and the lasting sequelae that result from infection with Neisseria gonorrhoeae…”
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Development of a non-biased, high-throughput ELISA for the rapid evaluation of immunogenicity and cross-reactivity by Fegan, Jamie E., Yu, Rong-hua, Islam, Epshita A., Schryvers, Anthony B.

“…Traditional ELISA-based protein analysis has been predicated on the assumption that proteins bind randomly to the solid surface of the ELISA plate polymer…”
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Utility of Hybrid Transferrin Binding Protein Antigens for Protection Against Pathogenic Neisseria Species by Fegan, Jamie E, Calmettes, Charles, Islam, Epshita A, Ahn, Sang Kyun, Chaudhuri, Somshukla, Yu, Rong-Hua, Gray-Owen, Scott D, Moraes, Trevor F, Schryvers, Anthony B

“…The surface transferrin receptor proteins from have been recognized as ideal vaccine targets due to their critical role in survival in the human male…”
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Specific Binding to Differentially Expressed Human Carcinoembryonic Antigen-Related Cell Adhesion Molecules Determines the Outcome of Neisseria gonorrhoeae Infections along the Female Reproductive Tract by Islam, Epshita A, Anipindi, Varun C, Francis, Ian, Shaik-Dasthagirisaheb, Yazdan, Xu, Stacey, Leung, Nelly, Sintsova, Anna, Amin, Mohsen, Kaushic, Charu, Wetzler, Lee M, Gray-Owen, Scott D

“…The gonococcal Opa proteins are an antigenically variable family of surface adhesins that bind human carcinoembryonic antigen-related cell adhesion molecule 1…”
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Developing a PmSLP3-based vaccine formulation that provides robust long-lasting protection against hemorrhagic septicemia-causing serogroup B and E strains of Pasteurella multocida in cattle by Fegan, Jamie E, Waeckerlin, Regula C, Tesfaw, Liyuwork, Islam, Epshita A, Deresse, Getaw, Dufera, Dawit, Assefa, Eyob, Woldemedhin, Wubet, Legesse, Abinet, Akalu, Mirtneh, Bayissa, Berecha, Nguyen, Quynh Huong, Ng, Dixon, Ahn, Sang Kyun, Schryvers, Anthony B, Tefera, Takele A, Moraes, Trevor F, Gray-Owen, Scott D

“…is a bacterial pathogen that causes a variety of infections across diverse animal species, with one of the most devastating associated diseases being…”
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Murine host response to Neisseria gonorrhoeae upper genital tract infection reveals a common transcriptional signature, plus distinct inflammatory responses that vary between reproductive cycle phases by Francis, Ian P, Islam, Epshita A, Gower, Adam C, Shaik-Dasthagirisaheb, Yazdani B, Gray-Owen, Scott D, Wetzler, Lee M

“…The emergence of fully antimicrobial resistant Neisseria gonorrhoeae has led global public health agencies to identify a critical need for next generation…”
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In vivo adaptation and persistence of Neisseria meningitidis within the nasopharyngeal mucosa by Johswich, Kay O, McCaw, Shannon E, Islam, Epshita, Sintsova, Anna, Gu, Angel, Shively, John E, Gray-Owen, Scott D

“…Neisseria meningitidis (Nme) asymptomatically colonizes the human nasopharynx, yet can initiate rapidly-progressing sepsis and meningitis in rare instances…”
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GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cells by Cain, Jason E, Islam, Epshita, Haxho, Fiona, Chen, Lin, Bridgewater, Darren, Nieuwenhuis, Erica, Hui, Chi-Chung, Rosenblum, Norman D

“…Truncating GLI3 mutations in Pallister-Hall Syndrome with renal malformation suggests a requirement for Hedgehog signaling during renal development…”
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GLI3 repressor controls functional development of the mouse ureter by Cain, Jason E, Islam, Epshita, Haxho, Fiona, Blake, Joshua, Rosenblum, Norman D

“…Obstructive and nonobstructive forms of hydronephrosis (increased diameter of the renal pelvis and calyces) and hydroureter (dilatation of the ureter) are the…”
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Host response to Neisseria gonorrhoeae infection in female wild type mice is dictated by the dominant sex hormone by Francis, Ian P, Shaik-Dasthagirisaheb, Yazdan, Islam, Epshita, Gray-Owen, Scott D, Wetzler, Lee

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Neisseria gonorrhoeae selectively suppresses the development of Th1 and Th2 cells, and enhances Th17 cell responses, through TGF-β-dependent mechanisms by Liu, Y, Islam, E A, Jarvis, G A, Gray-Owen, S D, Russell, M W

“…Infection with Neisseria gonorrhoeae does not induce specific immunity or immune memory. Our previous studies in a murine model of vaginal gonococcal infection…”
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Global Analysis of Neutrophil Responses to Neisseria gonorrhoeae Reveals a Self-Propagating Inflammatory Program: e1004341 by Sintsova, Anna, Sarantis, Helen, Islam, Epshita A, Sun, Chun Xiang, Amin, Mohsen, Chan, Carlos HF, Stanners, Clifford P, Glogauer, Michael, Gray-Owen, Scott D

“…An overwhelming neutrophil-driven response causes both acute symptoms and the lasting sequelae that result from infection with Neisseria gonorrhoeae…”
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In Vivo Adaptation and Persistence of Neisseria meningitidis within the Nasopharyngeal Mucosa: e1003509 by Johswich, Kay O, McCaw, Shannon E, Islam, Epshita, Sintsova, Anna, Gu, Angel, Shively, John E, Gray-Owen, Scott D

“…Neisseria meningitidis (Nme) asymptomatically colonizes the human nasopharynx, yet can initiate rapidly-progressing sepsis and meningitis in rare instances…”
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Novel Mouse Models to Reveal Pathogenic Determinants that Contribute to Gonococcal Infection and Pelvic Inflammatory Disease by Islam, Epshita Anher

“…Neisseria gonorrhoeae (Ngo) is an obligate human pathogen that causes gonorrhea, one of the most prevalent sexually transmitted infections worldwide. In women,…”
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GLI3 repressor controls functional development of the mouse ureter by Cain, Jason E, Islam, Epshita, Haxho, Fiona, Blake, Joshua, Rosenblum, Norman D

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