Search Results - "Iskusnykh, Igor Y"

Glutathione in Brain Disorders and Aging by Iskusnykh, Igor Y, Zakharova, Anastasia A, Pathak, Dhruba

“…Glutathione is a remarkably functional molecule with diverse features, which include being an antioxidant, a regulator of DNA synthesis and repair, a protector…”
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Unified rhombic lip origins of group 3 and group 4 medulloblastoma by Smith, Kyle S., Bihannic, Laure, Gudenas, Brian L., Haldipur, Parthiv, Tao, Ran, Gao, Qingsong, Li, Yiran, Aldinger, Kimberly A., Iskusnykh, Igor Y., Chizhikov, Victor V., Scoggins, Matthew, Zhang, Silu, Edwards, Angela, Deng, Mei, Glass, Ian A., Overman, Lynne M., Millman, Jake, Sjoboen, Alexandria H., Hadley, Jennifer, Golser, Joseph, Mankad, Kshitij, Sheppard, Heather, Onar-Thomas, Arzu, Gajjar, Amar, Robinson, Giles W., Hovestadt, Volker, Orr, Brent A., Patay, Zoltán, Millen, Kathleen J., Northcott, Paul A.

“…Medulloblastoma, a malignant childhood cerebellar tumour, segregates molecularly into biologically distinct subgroups, suggesting that a personalized approach…”
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Cortical hem signaling center: functions, development, and potential implications for evolution and brain disorders by Chizhikov, Victor V, Iskusnykh, Igor Y

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Aging, Neurodegenerative Disorders, and Cerebellum by Iskusnykh, Igor Y, Zakharova, Anastasia A, Kryl'skii, Evgenii D, Popova, Tatyana N

“…An important part of the central nervous system (CNS), the cerebellum is involved in motor control, learning, reflex adaptation, and cognition. Diminished…”
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Cerebellar development after preterm birth by Iskusnykh, Igor Y, Chizhikov, Victor V

“…Preterm birth and its complications and the associated adverse factors, including brain hemorrhage, inflammation, and the side effects of medical treatments,…”
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Transformation of the cerebellum into more ventral brainstem fates causes cerebellar agenesis in the absence of Ptf1a function by Millen, Kathleen J, Steshina, Ekaterina Y, Iskusnykh, Igor Y, Chizhikov, Victor V

“…Model organism studies have demonstrated that cell fate specification decisions play an important role in normal brain development. Their role in human…”
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Early dorsomedial tissue interactions regulate gyrification of distal neocortex by Chizhikov, Victor V., Iskusnykh, Igor Y., Steshina, Ekaterina Y., Fattakhov, Nikolai, Lindgren, Anne G., Shetty, Ashwin S., Roy, Achira, Tole, Shubha, Millen, Kathleen J.

“…The extent of neocortical gyrification is an important determinant of a species’ cognitive abilities, yet the mechanisms regulating cortical gyrification are…”
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Lmx1a is a master regulator of the cortical hem by Iskusnykh, Igor Y, Fattakhov, Nikolai, Li, Yiran, Bihannic, Laure, Kirchner, Matthew K, Steshina, Ekaterina Y, Northcott, Paul A, Chizhikov, Victor V

“…Development of the nervous system depends on signaling centers - specialized cellular populations that produce secreted molecules to regulate neurogenesis in…”
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Effects of Phosphatidylserine Source of Docosahexaenoic Acid on Cerebellar Development in Preterm Pigs by Chizhikov, Daniel, Buddington, Randal K, Iskusnykh, Igor Y

“…Preterm birth, a major contributor to infant mortality and morbidity, impairs development of the cerebellum, the brain region involved in cognitive processing…”
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Novel Antioxidant, Deethylated Ethoxyquin, Protects against Carbon Tetrachloride Induced Hepatotoxicity in Rats by Inhibiting NLRP3 Inflammasome Activation and Apoptosis by Iskusnykh, Igor Y, Kryl'skii, Evgenii D, Brazhnikova, Darya A, Popova, Tatyana N, Shikhaliev, Khidmet S, Shulgin, Konstantin K, Matasova, Larisa V, Popov, Sergey S, Zhaglin, Dmitry A, Zakharova, Anastasia A, Popova, Nelli R, Fattakhov, Nikolai

“…Inflammation and an increase in antioxidant responses mediated by oxidative stress play an important role in the pathogenesis of acute liver injury (ALI). We…”
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Organ Growth and Intestinal Functions of Preterm Pigs Fed Low and High Protein Formulas With or Without Supplemental Leucine or Hydroxymethylbutyrate as Growth Promoters by Buddington, Randal K., Yakimkova, Taisiya, Adebiyi, Adebowale, Chizhikov, Victor V., Iskusnykh, Igor Y., Buddington, Karyl K.

“…The goal of enteral nutritional support for infants born preterm or small for gestational age (SGA) is to achieve normal growth and development. Yet, this is…”
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Lmx1a and Lmx1b are Redundantly Required for the Development of Multiple Components of the Mammalian Auditory System by Chizhikov, Victor V., Iskusnykh, Igor Y., Fattakhov, Nikolai, Fritzsch, Bernd

“…•Combined loss of Lmx1a/b disrupts auditory inner ear development, preventing formation of the organ of Corti.•Loss of Lmx1a and Lmx1b leads to milder inner…”
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Ptf1a expression is necessary for correct targeting of spiral ganglion neurons within the cochlear nuclei by Elliott, Karen L., Iskusnykh, Igor Y., Chizhikov, Victor V., Fritzsch, Bernd

“…•A transient posterior expansion of inner ear projections to the DCN was observed in Ptf1a mutants.•Broader central projections to the AVCN/PVCN were observed…”
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Preterm birth disrupts cerebellar development by affecting granule cell proliferation program and Bergmann glia by Iskusnykh, Igor Y., Buddington, Randal K., Chizhikov, Victor V.

“…Preterm birth is a leading cause of long-term motor and cognitive deficits. Clinical studies suggest that some of these deficits result from disruption of…”
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Intrauterine growth restriction compromises cerebellar development by affecting radial migration of granule cells via the JamC/Pard3a molecular pathway by Iskusnykh, Igor Y., Fattakhov, Nikolai, Buddington, Randal K., Chizhikov, Victor V.

“…Intrauterine growth restriction (IUGR) affects ~10% of human pregnancies, results in infants born small for gestational age (SGA), and is associated with motor…”
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Molecular ontology of the parabrachial nucleus by Karthik, Samyukta, Huang, Dake, Delgado, Yaritza, Laing, Justin J., Peltekian, Lila, Iverson, Gabrielle N., Grady, Fillan, Miller, Rebecca L., McCann, Corey M., Fritzsch, Bernd, Iskusnykh, Igor Y., Chizhikov, Victor V., Geerling, Joel C.

“…Diverse neurons in the parabrachial nucleus (PB) communicate with widespread brain regions. Despite evidence linking them to a variety of homeostatic…”
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Expression of Glutathione Peroxidase and Glutathione Reductase and Level of Free Radical Processes under Toxic Hepatitis in Rats by Iskusnykh, Igor Y., Popova, Tatyana N., Agarkov, Aleksander A., Pinheiro de Carvalho, Miguel Â. A., Rjevskiy, Stanislav G.

“…Correlation between intensity of free radical processes estimated by biochemiluminesce parameters, content of lipoperoxidation products, and changes of…”
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Loss of Ptf1a Leads to a Widespread Cell-Fate Misspecification in the Brainstem, Affecting the Development of Somatosensory and Viscerosensory Nuclei by Iskusnykh, Igor Y, Steshina, Ekaterina Y, Chizhikov, Victor V

“…The brainstem contains diverse neuronal populations that regulate a wide range of processes vital to the organism. Proper cell-fate specification decisions are…”
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A Phosphatidylserine Source of Docosahexanoic Acid Improves Neurodevelopment and Survival of Preterm Pigs by Buddington, Randal K, Chizhikov, Victor V, Iskusnykh, Igor Y, Sable, Helen J, Sable, Jeffrey J, Holloway, Zade R, Blumenfeld Katzir, Tamar, van der Merwe, Marie, Yakimkova, Taisiya, Buddington, Karyl K, Lifshitz, Yael, Tessler, Shoshi, Gilbert, Ariel

“…The amount, composition, and sources of nutrition support provided to preterm infants is critical for normal growth and development, and particularly for…”
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Transformation of the cerebellum into more ventral brainstem fates causes cerebellar agenesis in the absence of Ptf1a function by Millen, Kathleen J., Steshina, Ekaterina Y., Iskusnykh, Igor Y., Chizhikov, Victor V.

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