Search Results - "Iskra, Brian S."

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  1. 1
    Development and characterization of a mass cytometry panel for detecting the effect of acute doxorubicin exposure on murine cardiac nonmyocytes

    Development and characterization of a mass cytometry panel for detecting the effect of acute doxorubicin exposure on murine cardiac nonmyocytes by Iskra, Brian S, Davis, Logan, Miller, Henry E, Chiu, Yu-Chiao, Bishop, Alexander J R, Chen, Yidong, Aune, Gregory J

    “…Childhood cancer survivors (CCSs) face lifelong side effects related to their treatment with chemotherapy. Anthracycline agents, such as doxorubicin (DOX), are…”
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  2. 2
    Reconstruction of Ewing Sarcoma Developmental Context from Mass-Scale Transcriptomics Reveals Characteristics of EWSR1-FLI1 Permissibility

    Reconstruction of Ewing Sarcoma Developmental Context from Mass-Scale Transcriptomics Reveals Characteristics of EWSR1-FLI1 Permissibility by Miller, Henry E, Gorthi, Aparna, Bassani, Nicklas, Lawrence, Liesl A, Iskra, Brian S, Bishop, Alexander J R

    Published in Cancers (11-04-2020)
    “…Ewing sarcoma is an aggressive pediatric cancer of enigmatic cellular origins typically resulting from a single translocation event t (11; 22) (q24; q12). The…”
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  3. 3
    Factors Affecting Outcomes in Geriatric Traumatic Subdural Hematoma in a Neurosurgical Intensive Care Unit

    Factors Affecting Outcomes in Geriatric Traumatic Subdural Hematoma in a Neurosurgical Intensive Care Unit by Kanakia, Kunal P., Wells, Anne Marie, Tchoulhakian, Missak, Iskra, Brian S., Kaculini, Christian, Tavakoli-Samour, Samon, Boyd, Jacob T., Hafeez, Shaheryar, Seifi, Ali, Dengler, Bradley A.

    Published in World neurosurgery (01-02-2022)
    “…Geriatric patients (age ≥65 years) who sustain a traumatic brain injury have an increased risk of poor outcomes and higher mortality compared with younger…”
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  4. 4
    Predicting and characterizing a cancer dependency map of tumors with deep learning

    Predicting and characterizing a cancer dependency map of tumors with deep learning by Chiu, Yu-Chiao, Zheng, Siyuan, Wang, Li-Ju, Iskra, Brian S, Rao, Manjeet K, Houghton, Peter J, Huang, Yufei, Chen, Yidong

    Published in Science advances (01-08-2021)
    “…Genome-wide loss-of-function screens have revealed genes essential for cancer cell proliferation, called cancer dependencies. It remains challenging to link…”
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  5. 5
    Assessing the Significance of Mitochondrial Dysfunction in Non-Myocytes in Doxorubicin Induced-Cardiac Injury

    Assessing the Significance of Mitochondrial Dysfunction in Non-Myocytes in Doxorubicin Induced-Cardiac Injury by Iskra, Brian S

    Published 01-01-2020
    “…Childhood cancer survivors have an increased likelihood of developing cardiac disease related to their treatment. Anthracycline agents, such as doxorubicin,…”
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