Search Results - "Iskander, George"
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Investigating the Behaviour and Strength of Unbonded Pre-tensioned RC Slabs Subject to Flexural Loads
Published in Electronic journal of structural engineering (03-06-2024)“…Unbonded pre-tensioned systems, in which tendons are greased and wrapped in plastic sheathing, have several benefits in comparison to bonded systems. However,…”
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Examining ACI Development Length and Strength Provisions for RC Slabs Strengthened with NSM GFRP
Published in Electronic journal of structural engineering (06-05-2024)“…This study aims to investigate the strengthening effect of GFRP bars on the capacity of RC slabs when subject to flexure loading. The objective is to show the…”
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3
Teleportation Systems Toward a Quantum Internet
Published in PRX quantum (04-12-2020)“…Quantum teleportation is essential for many quantum information technologies, including long-distance quantum networks. Using fiber-coupled devices, including…”
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Novel Mechanism of Cytotoxicity for the Selective Selenosemicarbazone, 2‑Acetylpyridine 4,4-Dimethyl-3-selenosemicarbazone (Ap44mSe): Lysosomal Membrane Permeabilization
Published in Journal of medicinal chemistry (14-01-2016)“…Selenosemicarbazones show marked antitumor activity. However, their mechanism of action remains unknown. We examined the medicinal chemistry of the…”
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Indole-based novel small molecules for the modulation of bacterial signalling pathways
Published in Organic & biomolecular chemistry (21-01-2015)“…Gram-negative bacteria such as Pseudomonas aeruginosa use N-acylated L-homoserine lactones (AHLs) as autoinducers (AIs) for quorum sensing (QS), a major…”
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The Role of Orientation of Surface Bound Dihydropyrrol-2-ones (DHP) on Biological Activity
Published in Molecules (Basel, Switzerland) (23-07-2019)“…Quorum sensing (QS) signaling system is important for bacterial growth, adhesion, and biofilm formation resulting in numerous infectious diseases…”
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Design and Synthesis of Lactams Derived from Mucochloric and Mucobromic Acids as Pseudomonas aeruginosa Quorum Sensing Inhibitors
Published in Molecules (Basel, Switzerland) (07-05-2018)“…Bacterial infections, particularly hospital-acquired infections caused by , have become a global threat with a high mortality rate. Gram-negative bacteria…”
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Synthesis of Alkyne-Substituted Dihydropyrrolones as Bacterial Quorum-Sensing Inhibitors of Pseudomonas aeruginosa
Published in Antibiotics (Basel) (25-01-2022)“…The Quorum-sensing system in is responsible for the pathogenicity and the production of virulence factors and biofilm formation. Dihydropyrrolones were…”
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Novel Seleno- and Thio-Urea Containing Dihydropyrrol-2-One Analogues as Antibacterial Agents
Published in Antibiotics (Basel) (19-03-2021)“…The quorum sensing (QS) system in multi-drug-resistant bacteria such as is primarily responsible for the development of antibiotic resistance and is considered…”
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Synthesis of novel isoflavene–propranolol hybrids as anti-tumor agents
Published in Bioorganic & medicinal chemistry (01-04-2013)“…Isoflavene–propranolol hybrid molecules were developed as potentially novel anti-tumour agents. Isoflavene itself has potent anti-cancer activity while…”
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Hybrids of acylated homoserine lactone and nitric oxide donors as inhibitors of quorum sensing and virulence factors in Pseudomonas aeruginosa
Published in Organic & biomolecular chemistry (14-10-2015)“…Pseudomonas aeruginosa is an opportunistic pathogen causing a variety of life-threatening diseases such as cystic fibrosis and nosocomial infections in burn…”
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12
Using the weighted max–min approach for stochastic fuzzy goal programming: A case of fuzzy weights
Published in Applied mathematics and computation (01-05-2007)“…In this paper, a suggested concept of the weighted max–min approach [C.-C. Lin, A weighted max–min model for fuzzy goal programming, Fuzzy Sets and Systems 142…”
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13
Experimental investigation of the influence of head joints and grouting conditions on the shear strength of concrete block masonry
Published in Construction & building materials (12-01-2024)“…The nonlinear composite nature of masonry has limited theoretical understanding of material shear strength – especially with concrete block, where minimal…”
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14
Instituting a robot-assisted surgery programme at a tertiary care cancer centre
Published in The international journal of medical robotics + computer assisted surgery (01-09-2010)“…Background The initial experience of a gynaecological oncology robotic surgery programme at a tertiary care cancer centre is described. Methods A retrospective…”
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15
Simplified analytical solution for point load acting behind a cantilever wall
Published in International journal for numerical and analytical methods in geomechanics (25-02-2012)“…SUMMARY The analysis of earth pressure resulting from an applied point load behind a retaining wall is to be carried out in three dimensions as the earth…”
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16
Picosecond Synchronization System for the Distribution of Photon Pairs through a Fiber Link between Fermilab and Argonne National Laboratories
Published in IEEE journal of quantum electronics (01-08-2023)“…We demonstrate a three-node quantum network for C-band photon pairs using 2 pairs of 59 km of deployed fiber between Fermi and Argonne National Laboratories…”
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Copper-mediated Chan-Evans-Lam N-arylation of 5-methylene-4-aryl-1,5-dihydro-2H-pyrrol-2-one derivatives
Published in Tetrahedron letters (28-02-2018)“…[Display omitted] •A simple and efficient procedure for the N-arylation of dihydropyrrol-2-one (DHP) derivatives has been developed.•This method employed the…”
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Dihydropyrrolones as bacterial quorum sensing inhibitors
Published in Bioorganic & medicinal chemistry letters (01-05-2019)“…[Display omitted] Bacteria regulate their pathogenicity and biofilm formation through quorum sensing (QS), which is an intercellular communication system…”
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19
Synthesis and copolymerization of methacryloyl hydroxamic acids
Published in Journal of applied polymer science (24-10-2000)“…Three methacryloyl hydroxamic acids were prepared and homopolymerized yielding polymers which readily formed complexes with Fe3+. The amount of hydroxamic acid…”
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Design, Synthesis, and Evaluation of Fimbrolide–Nitric Oxide Donor Hybrids as Antimicrobial Agents
Published in Journal of medicinal chemistry (12-12-2013)“…Fimbrolides from marine algae have shown promising activity against quorum sensing (QS), a chief regulatory and communication system in bacteria controlling…”
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