Search Results - "Isidoro García, M"

PTGDR gene in asthma: a functional, genetic, and epigenetic study by Isidoro‐García, M., Sanz, C., García‐Solaesa, V., Pascual, M., Pescador, D. B., Lorente, F., Dávila, I.

“…To cite this article: Isidoro‐García M, Sanz C, García‐Solaesa V, Pascual M, Pescador DB, Lorente F, Dávila I. PTGDR gene in asthma: a functional, genetic, and…”
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Promoter Genotyping and mRNA Expression - Based Analysis of the PTGDR Gene in Allergy by San Segundo-Val, I, García-Sánchez, A, Sanz, C, Cornejo-García, J A, Isidoro-García, M, Dávila, I

“…Prostaglandin D2 receptors are acquiring a relevant role as potential therapeutic targets in allergy. PTGDR has been described as a candidate gene in allergic…”
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Update on the Genetic Basis of Drug Hypersensitivity Reactions by Jurado-Escobar, R, Perkins, J R, García-Martín, E, Isidoro-García, M, Doña, I, Torres, M J, Cornejo-García, J A

“…Drug hypersensitivity reactions (DHRs) are unpredictable, complex responses to medicines in predisposed individuals. They represent a major health problem…”
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Polymorphisms of the IL12B, IL1B, and TNFA genes and susceptibility to asthma by Padrón-Morales, J, Sanz, C, Dávila, I, Muñoz-Bellido, F, Lorente, F, Isidoro-García, M

“…Asthma is one of the most common chronic inflammatory diseases in developed countries. Susceptibility to asthma is associated with interaction between multiple…”
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Genome-wide association studies (GWAS) and their importance in asthma by García-Sánchez, A, Isidoro-García, M, García-Solaesa, V, Sanz, C, Hernández-Hernández, L, Padrón-Morales, J, Lorente-Toledano, F, Dávila, I

“…Asthma is a complex disease determined by the interaction of different genes and environmental factors. The first genetic investigations in asthma were…”
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Tryptase: genetic and functional considerations by Hernández-Hernández, L, Sanz, C, García-Solaesa, V, Padrón, J, García-Sánchez, A, Dávila, I, Isidoro-García, M, Lorente, F

“…Tryptase is one of the main proteases located in the secretory granules of the mast cells, and is released through degranulation. It is therefore assumed to…”
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The prostaglandin D2 receptor (PTGDR) gene in asthma and allergic diseases by García-Solaesa, V, Sanz-Lozano, C, Padrón-Morales, J, Hernández-Hernández, L, García-Sánchez, A, Rivera-Reigada, M L, Dávila-González, I, Lorente-Toledano, F, Isidoro-García, M

“…The prostaglandin D2 receptor (PTGDR) gene has been associated to asthma and related phenotypes by linking and association studies. Functional studies…”
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Promoter genetic variants of prostanoid DP receptor (PTGDR) gene in patients with asthma by Sanz, C., Isidoro‐García, M., Dávila, I., Moreno, E., Laffond, E., Ávila, C., Lorente, F.

“…Background:  PTGDR gene has been identified as an asthma‐susceptibility gene. Recently, functional genetic variants have been associated with asthma. The…”
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Genetic association study in nasal polyposis by Benito Pescador, D, Isidoro-García, M, García-Solaesa, V, Pascual de Pedro, M, Sanz, C, Hernández-Hernández, L, Sánchez-López, J, Lorente, S F, Picado, C, Valero, A, Dávila, I

“…Nasal polyposis (NP) is a chronic inflammatory disease of the upper airways with a variable clinical course and unknown pathogenesis that often coexists with…”
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402 Effect of Antenatal Corticosteroids in Activity and Expression of Secretory Phospholipase A2 and TNF Alfa in Lung of Newborn Rats by Remesal, A, Feliciano, L San, Luca, D de, Benito, D, Minucci, A, Isidoro-García, M, Ludeña, D

“…Introduction The sPLA2 plays an important role in the development of acute respiratory distress syndrome. It is regulated by many factors including steroids…”
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Retinoic Acid Modulates PTGDR Promoter Activity by García-Sánchez, A, Marcos-Vadillo, E, Sanz, C, Hernández-Hernández, L, Cerutti-Müller, G, Marqués-García, F, Lorente, F, Isidoro-García, M, Dávila, I

“…Vitamin A has been linked to the development of allergic diseases although its role is not fully understood, Retinoic acid (RA), a metabolite of Vitamin A, has…”
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Implications of cytokine genes in allergic asthma by Padrón-Morales, J, García-Solaesa, V, Isidoro-García, M, Hernández-Hernández, L, García-Sánchez, A, Hincapié-López, G, Lorente-Toledano, F, Dávila, I, Sanz, C

“…Asthma is a complex disease involving numerous mediator molecules and effector cells, in combination with a range of environmental determining factors…”
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(CCTTT)n polymorphism of NOS2A in nasal polyposis and asthma: a case-control study by Pascual, M, Sanz, C, Isidoro-García, M, Dávila, I, Moreno, E, Laffond, E, Lorente, F

“…Nitric Oxide (NO) has been proposed as an important signaling molecule. NO produced by the inducible NO synthase enzyme NOS2A is generated at high levels in…”
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Do genetic factors determine atopy or allergy? by Lorente, F, Isidoro-García, M, Macias, E, Dávila, I

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Interactions between genes and the environment. Epigenetics in allergy by Isidoro-García, M, Dávila-González, I, Pascual de Pedro, M, Sanz-Lozano, C, Lorente-Toledano, F

“…Epigenetics is defined as those inheritable changes occurring in gene expression, without actual modification in the genic DNA sequence. Epigenetic factors are…”
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Analysis of 927T > C CYSLTR1 and -444A > C LTC4S polymorphisms in children with asthma by Arriba-Méndez, S, Sanz, C, Isidoro-García, M, Pascual, M, Avila, C, Dávila, I, Lorente, F

“…The cysteinyl leukotrienes (Cys-LTs) are potent inflammatory mediators in asthma. It has been suggested that the different response of patients to Cys-LTs…”
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Atopy Can Be an Interfering Factor in Genetic Association Studies of ß-Lactam Allergy by Rivera-Reigada, M L, Moreno, E, Sanz, C, García-Sánchez, A, Cornejo-García, J A, Dávila, I, Isidoro-García, M

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Expression of ZFOR1, a δ-opioid receptor, in the central nervous system of the zebrafish (Danio rerio) by Porteros, A., García-Isidoro, M., Barrallo, A., González-Sarmiento, R., Rodríguez, R.E.

“…Opioid receptors, besides mediating the effects of analgesic compounds, are involved in drug addiction. Although a large amount of work has been done studying…”
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Incidence of chromosome numerical changes in multiple myeloma: fluorescence in situ hybridization analysis using 15 chromosome- specific probes by Tabernero, D, San Miguel, JF, Garcia-Sanz, M, Najera, L, Garcia-Isidoro, M, Perez- Simon, JA, Gonzalez, M, Wiegant, J, Raap, AK, Orfao, A

“…The presence of complex karotypes with frequent numerical and structural abnormalities has been reported in 20 to 50% of multiple myeloma (MM) patients. This…”
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Drug, genes and asthma: when variability matters by Dávila, I, Sanz, C, Isidoro García, M

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