Search Results - "Ishola, Azeez Olakunle"

Ketamine abrogates sensorimotor deficits and cytokine dysregulation in a chronic unpredictable mild stress model of depression by Edem, Edem Ekpenyong, Anyanwu, Collins-Kevin Chukwudi, Nebo, Kate Eberechukwu, Akinluyi, Elizabeth Toyin, Fafure, Adedamola Adediran, Ishola, Azeez Olakunle, Enye, Linus Anderson

“…Major depressive disorder (MDD) is a serious mental disorder with influence across the functional systems of the body. The pathogenesis of MDD has been known…”
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Effects of datumetine on hippocampal NMDAR activity by Ishola, Azeez Olakunle, Imam, Aminu, Ajao, Moyosore Salihu

“…Datumetine binds with NMDAR altering its calcium current. Acute exposure downregulates NMDAR signalling. [Display omitted] •Datura intoxication induces an…”
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Datumetine Preferentially Upregulates NMDAR Signalling Pathways in Different Brain Regions of Mice by Azeez Olakunle Ishola, Adedeji Enitan Adetunji, Abanum, Isaac Chukwunwike, Adeyemi, Adesola Akorede, Faleye, Caleb Kenechukwu, Martins, Jane Babale, Ogbe, Nnenna Chimdalu, Ogundipe, Toluwalase Cherish, Okewulonu, Karen Ezichi, Umo Emmanuel Okon, Ovbude, Deborah Irenoise, Akele, Richard Yomi, Naeemat Tolulope Omotade, Ajao, Moyosore Salihu

“…Background:We earlier reported that datumetine possesses binding affinity with NMDAR and that 14-day exposure to datumetine altered NMDAR signalling by…”
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Datumetine Preferentially Upregulates N-methyl-D-aspartate Receptor Signalling Pathways in Different Brain Regions of Mice by Olakunle Ishola, Azeez, Enitan Adetunji, Adedeji, Chukwunwike Abanum, Isaac, Akorede Adeyemi, Adesola, Kenechukwu Faleye, Caleb, Babale Martins, Jane, Chimdalu Ogbe, Nnenna, Cherish Ogundipe, Toluwalase, Ezichi Okewulonu, Karen, Emmanuel Okon, Umo, Irenoise Ovbude, Deborah, Yomi Akele, Richard, Tolulope Omotade, Naeemat, Salihu Ajao, Moyosore

“…Introduction: We previously reported that datumetine possesses binding affinity with N-methyl-D-aspartate receptor (NMDAR) and that 14-day exposure to…”
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Exposure to radio-frequency electromagnetic waves alters acetylcholinesterase gene expression, exploratory and motor coordination-linked behaviour in male rats by Obajuluwa, Adejoke Olukayode, Akinyemi, Ayodele Jacob, Afolabi, Olakunle Bamikole, Adekoya, Khalid, Sanya, Joseph Olurotimi, Ishola, Azeez Olakunle

“…Humans in modern society are exposed to an ever-increasing number of electromagnetic fields (EMFs) and some studies have demonstrated that these waves can…”
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Differential oxidative stress thresholds distinguishes cellular response to vascular occlusion and chemotoxicity in vivo by Ogundele, Olalekan Michael, Wasiu Gbolahan, Balogun, Emmanuel Cobham, Ansa, Azeez Olakunle, Ishola, Abdulbasit, Amin

“…Background: A major effect of cyanide toxicity (CN) and vascular occlusion (VO) is the production of reactive oxygen species (ROS) linked with a defective…”
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Cadmium Increases the Sensitivity of Adolescent Female Mice to Nicotine-Related Behavioral Deficits by Ajonijebu, Duyilemi Chris, Ishola, Azeez Olakunle, Olatunji, Babawale Peter, Adeniyi, Philip Adeyemi, Ogundele, Olalekan Michael

“…This study investigates spatial and nonspatial working memory, anxiety related behavior, and motor activities in cadmium and/or nicotine exposed female…”
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Datumetine exposure alters hippocampal neurotransmitters system in C57BL/6 mice by Ishola, Azeez Olakunle, Imam, Aminu, Ajao, Moyosore Salihu

“…Our previous study showed that datumetine modulates NMDAR activity with long term exposure leading to memory deficit and altered NMDAR signaling. We aim to…”
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Tetracarpidium conophorum Müll. Arg modulates sexual behaviour and biochemical parameters relevant to sexual function in male Wistar rats by Olabiyi, Ayodeji Augustine, Oboh, Ganiyu, Ishola, Azeez Olakunle, Adeniyi, Philip Adeyemi, Boligon, Aline Augusti

“…Walnut (Tetracarpidium conophorum Müll. Arg) has been reported to be an essential ingredient in folklore medicine for sexual enhancement with little scientific…”
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Nicotine–cadmium exposure alters working memory, motor function and increased anxiety in adolescent female mice by Adeniyi, Philip Adeyemi, Olatunji, Babawale Peter, Ishola, Azeez Olakunle, Ajonijebu, Duyilemi Chris, Ogundele, Olalekan Michael

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NMDA R/+ VDR pharmacological phenotype as a novel therapeutic target in relieving motor–cognitive impairments in Parkinsonism by Michael, Ogundele Olalekan, Tarebi, Nanakumo Ednar, Olakunle, Ishola Azeez, Michael, Obende Oluwafemi, Anderson, Enya Linus, Gbolahan, Balogun Wasiu, Cobham, Ansa Emmanuel, Abdulbasit, Amin

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NMDA R/+VDR pharmacological phenotype as a novel therapeutic target in relieving motor-cognitive impairments in Parkinsonism by Ogundele, Olalekan Michael, Nanakumo, Ednar Tarebi, Ishola, Azeez Olakunle, Obende, Oluwafemi Michael, Enye, Linus Anderson, Balogun, Wasiu Gbolahan, Cobham, Ansa Emmanuel, Abdulbasit, Amin

“…Background: Parkinsonism describes Parkinson's disease and other associated degenerative changes in the brain resulting in movement disorders. The motor…”
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Motor and memory function in rat models of cyanide toxicity and vascular occlusion induced ischemic injury by Ogundele, Olalekan Michael, Adeniyi, Philip Adeyemi, Ajonijebu, Duyilemi Chris, Abdulbasit, Amin, Cobham, Ansa Emmanuel, Ishola, Azeez Olakunle, Balogun, Gbolahan Wasiu

“…Although oxidative stress is characteristic of global vascular occlusion and cyanide toxicity, the pattern of cerebral metabolism reconditioning and rate of…”
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Cerebrovascular changes in the rat brain in two models of ischemia by Ogundele, Olalekan Michael, Ajonijebu, Duyilemi Chris, Adeniyi, Philip Adeyemi, Alade, Olusoji Ibukunoluwa, Balogun, Wasiu Gbolahan, Cobham, Ansa Emmanuel, Ishola, Azeez Olakunle, Abdulbasit, Amin

“…Vascular occlusion and cyanide neurotoxicity induces oxidative stress and degeneration in the brain. This oxidant induced stress changes the vascular dynamics…”
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Mental and Growth Retardation following Prenatal Exposure to Oral Bitter Leaf (Vernonia amygdalina) Extract in Developing Wistar Rats by Balogun Wasiu Gbolahan, Gbadeyan Temitope Ruth, Ishola Azeez Olakunle, Atoyebi Aminat Temitayo, Cobham Ansa Emmanuel, Enaibe Bernard Ufuoma

“…Objective: The teratogenic influence of maternal exposure to bitter leaf on the morphology of foetal nervoussystem was studied. Methodology: In this study, we…”
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Mental and Growth Retardation following Prenatal Exposure to Oral Bitter Leaf (Vernonia amygdalina) Extract in Developing Wistar Rats by Balogun Wasiu Gbolahan, Gbadeyan Temitope Ruth, Ishola Azeez Olakunle, Atoyebi Aminat Temitayo, Cobham Ansa Emmanuel, Enaibe Bernard Ufuoma

“…Objective: The teratogenic influence of maternal exposure to bitter leaf on the morphology of foetal nervous system was studied. Methodology: In this study, we…”
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Mental and Growth Retardation following Prenatal Exposure to Oral Bitter Leaf (Vernonia amygdalina) Extract in Developing Wistar Rats by Balogun Wasiu Gbolahan, Gbadeyan Temitope Ruth, Ishola Azeez Olakunle, Atoyebi Aminat Temitayo, Cobham Ansa Emmanuel, Enaibe Bernard Ufuoma

“…Objective: The teratogenic influence of maternal exposure to bitter leaf on the morphology of foetal nervous system was studied. Methodology: In this study, we…”
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Retarded hippocampal development following prenatal exposure to ethanolic leaves extract of Datura metel in wistar rats by Ishola, Azeez Olakunle, Adeniyi, Philip Adeyemi

“…Datura metel contains atropine alkaloids and has been used to treat complication like asthma and, bronchitis, because of its anticholinergic properties. This…”
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Nicotine-Cadmium Interaction Alters Exploratory Motor Function and Increased Anxiety in Adult Male Mice by Chris Ajonijebu, Duyilemi, Adeyemi Adeniyi, Philip, Oloruntoba Adekeye, Adeshina, Peter Olatunji, Babawale, Olakunle Ishola, Azeez, Michael Ogundele, Olalekan

“…In this study we evaluated the time dependence in cadmium-nicotine interaction and its effect on motor function, anxiety linked behavioural changes, serum…”
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Lactobacillus plantarum mitigates sexual-reproductive deficits by modulating insulin receptor expression in the hypothalamic-pituitary-testicular axis of hyperinsulinemic mice by Edem, Edem Ekpenyong, Nathaniel, Blessing Uyo, Nebo, Kate Eberechukwu, Obisesan, Abiola Oluwatosin, Olabiyi, Ayodeji Augustine, Akinluyi, Elizabeth Toyin, Ishola, Azeez Olakunle

“…Hyperinsulinemia increases the risk factor of diabetes and infertility at a manifold. has several medical significances with limited reports. Hence, this study…”
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