Search Results - "Ishikawa, Tomoyoshi"
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Influence of pH on Heat-Induced Aggregation and Degradation of Therapeutic Monoclonal Antibodies
Published in Biological & Pharmaceutical Bulletin (2010)“…Monoclonal antibodies are widely used for the treatment of various diseases, and because therapeutic monoclonal antibodies are stored in an aqueous solution or…”
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Prevention of Stirring-Induced Microparticle Formation in Monoclonal Antibody Solutions
Published in Biological & Pharmaceutical Bulletin (2010)“…Monoclonal antibodies are being widely used for the treatment of various diseases. Microparticle formation in high-concentration protein solutions is a major…”
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3
Evaluation of the Aggregation States of Monoclonal Antibodies by Diverse and Complementary Methods
Published in Biological & Pharmaceutical Bulletin (2011)“…Therapeutic monoclonal antibodies (MAbs) with high specificity and fewer adverse effects are becoming widely used for the treatment of various diseases. MAbs…”
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4
Peroxiredoxin I expression in human thyroid tumors
Published in Cancer letters (18-10-1999)“…Peroxiredoxin I (Prx I) is newly discovered oxidative stress inducible protein, having a thioredoxin peroxidase activity. The Prx I expression level in 107…”
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Inactivation ofp16/CDKN2 andp15/MTS2 genes in different histological types and clinical stages of primary ovarian tumors
Published in International journal of cancer (20-12-1996)Get full text
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6
Quantitation of thyroid peroxidase mRNA in peripheral blood for early detection of thyroid papillary carcinoma
Published in Thyroid (New York, N.Y.) (01-05-2006)“…We applied quantitative reverse transcriptase-polymerase chain reaction (RT-PCR) to detect tissue-specific mRNAs in circulating cancer cells for the diagnosis…”
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Enhanced antitumor potency of polyethylene glycolylated tumor necrosis factor-alpha: a novel polymer-conjugation technique with a reversible amino-protective reagent
Published in The Journal of pharmacology and experimental therapeutics (01-07-1999)“…We attempted to develop a novel method for the chemical modification of cytokines with synthetic polymers to increase in vivo therapeutic efficacy. A…”
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1q23 gain is associated with progressive neuroblastoma resistant to aggressive treatment
Published in Genes chromosomes & cancer (01-07-1999)“…Neuroblastoma is one of the most common malignant tumors of childhood and is characterized by regressive and progressive disease. Genetic factors that define…”
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Molecular design of polyvinylpyrrolidone-conjugated interleukin-6 for enhancement of in vivo thrombopoietic activity in mice
Published in Journal of controlled release (03-09-2000)“…Functional polyvinylpyrrolidone (PVP) was synthesized as a novel polymeric modifier for polymer-conjugated cytokines, and its efficiency and applicability as a…”
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10
Inactivation of p16/CDKN2 and p15/MTS2 genes in different histological types and clinical stages of primary ovarian tumors
Published in International journal of cancer (20-12-1996)“…To define the involvement of p16/CDKN2 and p15/MTS2 inactivation in ovarian tumorigenesis and the association of these inactivation events with histological…”
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11
Expression of α-Fetoprotein and Prostate-specific Antigen Genes in Several Tissues and Detection of mRNAs in Normal Circulating Blood by Reverse Transcriptase-Polymerase Chain Reaction
Published in Japanese journal of clinical oncology (01-12-1998)“…Background: α-Fetoprotein (AFP) and prostate-specific antigen (PSA) in serum are widely used as tumor markers in the evaluation of prognosis and management of…”
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A direct-reading instrument for measurements of inductance and Q of ferrite core coils
Published in IEEE transactions on instrumentation and measurement (01-03-1981)“…A resonant circuit consisting of a coil to be tested and two capacitors in series, one of which is fixed and the other variable, is used to permit the direct…”
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