Search Results - "Ishikane, Shin"

Differentiation-inducing factor-1 potentiates adipogenic differentiation and attenuates the osteogenic differentiation of bone marrow-derived mesenchymal stem cells by Ishikane, Shin, Ikushima, Eigo, Igawa, Kazunobu, Tomooka, Katsuhiko, Takahashi-Yanaga, Fumi

“…Mesenchymal stem cells (MSCs) are an attractive cell source for tissue regeneration and repair. However, their low differentiation efficacy currently impedes…”
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2,5-Dimethylcelecoxib prevents isoprenaline-induced cardiomyocyte hypertrophy and cardiac fibroblast activation by inhibiting Akt-mediated GSK-3 phosphorylation by Morishige, Shoji, Takahashi-Yanaga, Fumi, Ishikane, Shin, Arioka, Masaki, Igawa, Kazunobu, Kuroo, Akihiro, Tomooka, Katsuhiko, Shiose, Akira, Sasaguri, Toshiyuki

“…[Display omitted] We previously reported that 2,5-dimethylcelecoxib (DM-celecoxib), a celecoxib derivative that is unable to inhibit cyclooxygenase-2,…”
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Development of a novel and rapid measurement system for growth differentiation factor-15, progranulin, and osteopontin in uterine sarcoma by Maeno, Mitsuo, Mizutani, Tetsuya, Tsuyoshi, Hideaki, Yamada, Shizuka, Ishikane, Shin, Kawabe, Shinya, Nishimura, Kengo, Yamada, Masami, Miyamoto, Kaoru, Yoshida, Yoshio

“…Uterine sarcomas are rare and aggressive gynecologic tumors with poor prognosis; therefore, early diagnosis is crucial for therapy. However, it is very…”
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Transcriptional regulation of genes related to progesterone production [Review] by Mizutani, Tetsuya, Ishikane, Shin, Kawabe, Shinya, Umezawa, Akihiro, Miyamoto, Kaoru

“…Steroid hormones are synthesized from cholesterol in various tissues, mainly in the adrenal glands and gonads. Because these lipid-soluble steroid hormones…”
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Comparison of angiogenic, cytoprotective, and immunosuppressive properties of human amnion- and chorion-derived mesenchymal stem cells by Yamahara, Kenichi, Harada, Kazuhiko, Ohshima, Makiko, Ishikane, Shin, Ohnishi, Shunsuke, Tsuda, Hidetoshi, Otani, Kentaro, Taguchi, Akihiko, Soma, Toshihiro, Ogawa, Hiroyasu, Katsuragi, Shinji, Yoshimatsu, Jun, Harada-Shiba, Mariko, Kangawa, Kenji, Ikeda, Tomoaki

“…Although mesenchymal stem cells (MSCs) can be obtained from the fetal membrane (FM), little information is available regarding biological differences in MSCs…”
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Angiotensin II promotes pulmonary metastasis of melanoma through the activation of adhesion molecules in vascular endothelial cells by Ishikane, Shin, Hosoda, Hiroshi, Nojiri, Takashi, Tokudome, Takeshi, Mizutani, Tetsuya, Miura, Koichi, Akitake, Yoshiharu, Kimura, Toru, Imamichi, Yoshitaka, Kawabe, Shinya, Toyohira, Yumiko, Yanagihara, Nobuyuki, Takahashi-Yanaga, Fumi, Miyazato, Mikiya, Miyamoto, Kaoru, Kangawa, Kenji

“…[Display omitted] Hypertension is considered as one of the cancer progressive factors, and often found comorbidity in cancer patients. Renin-angiotensin system…”
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Atrial natriuretic peptide prevents cancer metastasis through vascular endothelial cells by Nojiri, Takashi, Hosoda, Hiroshi, Tokudome, Takeshi, Miura, Koichi, Ishikane, Shin, Otani, Kentaro, Kishimoto, Ichiro, Shintani, Yasushi, Inoue, Masayoshi, Kimura, Toru, Sawabata, Noriyoshi, Minami, Masato, Nakagiri, Tomoyuki, Funaki, Soichiro, Takeuchi, Yukiyasu, Maeda, Hajime, Kidoya, Hiroyasu, Kiyonari, Hiroshi, Shioi, Go, Arai, Yuji, Hasegawa, Takeshi, Takakura, Nobuyuki, Hori, Megumi, Ohno, Yuko, Miyazato, Mikiya, Mochizuki, Naoki, Okumura, Meinoshin, Kangawa, Kenji

“…Significance Postoperative cancer recurrence is a major problem following curative cancer surgery. Perioperative systemic inflammation induces the adhesion of…”
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Allogeneic Transplantation of Fetal Membrane–Derived Mesenchymal Stem Cell Sheets Increases Neovascularization and Improves Cardiac Function after Myocardial Infarction in Rats by Ishikane, Shin, Hosoda, Hiroshi, Yamahara, Kenichi, Akitake, Yoshiharu, Kyoungsook, Jung, Mishima, Kenichi, Iwasaki, Katsunori, Fujiwara, Michihiro, Miyazato, Mikiya, Kangawa, Kenji, Ikeda, Tomoaki

“…BACKGROUNDMesenchymal stem cell (MSC) transplantation has been pursued as a new method to repair damaged myocardium. We focused on the fetal membrane (FM) as…”
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Development of a novel and rapid measurement system for growth differentiation factor-15, progranulin, and osteopontin in uterine sarcoma by Mitsuo Maeno, Tetsuya Mizutani, Hideaki Tsuyoshi, Shizuka Yamada, Shin Ishikane, Shinya Kawabe, Kengo Nishimura, Masami Yamada, Kaoru Miyamoto, Yoshio Yoshida

“…[Abstract.] Uterine sarcomas are rare and aggressive gynecologic tumors with poor prognosis ; therefore, early diagnosis is crucial for therapy. However, it is…”
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Identification of novel steroidogenic factor 1 (SF-1)-target genes and components of the SF-1 nuclear complex by Mizutani, Tetsuya, Kawabe, Shinya, Ishikane, Shin, Imamichi, Yoshitaka, Umezawa, Akihiro, Miyamoto, Kaoru

“…•Coordinated expression of all hGSTA family is regulated by SF-1 via altering higher-order chromatin structure.•Human GSTA1-1 and A3-3 work as the steroid…”
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Protective effects of C-type natriuretic peptide on cisplatin-induced nephrotoxicity in Mice by Kimura, Toru, Nojiri, Takashi, Hosoda, Hiroshi, Ishikane, Shin, Shintani, Yasushi, Inoue, Masayoshi, Miyazato, Mikiya, Okumura, Meinoshin, Kangawa, Kenji

“…Purpose Cisplatin is a highly effective chemotherapeutic agent used to treat various malignancies, but its utility is compromised by its nephrotoxicity. C-type…”
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Allogeneic Injection of Fetal Membrane‐Derived Mesenchymal Stem Cells Induces Therapeutic Angiogenesis in a Rat Model of Hind Limb Ischemia by Ishikane, Shin, Ohnishi, Shunsuke, Yamahara, Kenichi, Sada, Masaharu, Harada, Kazuhiko, Mishima, Kenichi, Iwasaki, Katsunori, Fujiwara, Michihiro, Kitamura, Soichiro, Nagaya, Noritoshi, Ikeda, Tomoaki

“…Bone marrow‐derived mesenchymal stem cells (BM‐MSC) have been demonstrated to be an attractive therapeutic cell source for tissue regeneration and repair…”
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Inhibitory effects of pine nodule extract and its component, SJ-2, on acetylcholine-induced catecholamine secretion and synthesis in bovine adrenal medullary cells by Li, Xiaojia, Horishita, Takafumi, Toyohira, Yumiko, Shao, Hui, Bai, Jie, Bo, Haixia, Song, Xinbo, Ishikane, Shin, Yoshinaga, Yukari, Satoh, Noriaki, Tsutsui, Masato, Yanagihara, Nobuyuki

“…Extract of pine nodules (matsufushi) formed by bark proliferation on the surface of trees of Pinus tabulaeformis or Pinus massoniana has been used as an…”
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Atrial natriuretic peptide inhibits lipopolysaccharide-induced acute lung injury by Nojiri, Takashi, Hosoda, Hiroshi, Tokudome, Takeshi, Miura, Koichi, Ishikane, Shin, Kimura, Toru, Shintani, Yasushi, Inoue, Masayoshi, Sawabata, Noriyoshi, Miyazato, Mikiya, Okumura, Meinoshin, Kangawa, Kenji

“…Abstract Objectives We recently reported that administration of atrial natriuretic peptide during the perioperative period has prophylactic effects with…”
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C-type natriuretic peptide attenuates lipopolysaccharide-induced acute lung injury in mice by Kimura, Toru, MD, Nojiri, Takashi, MD, PhD, Hosoda, Hiroshi, MD, PhD, Ishikane, Shin, PhD, Shintani, Yasushi, MD, PhD, Inoue, Masayoshi, MD, PhD, Miyazato, Mikiya, MD, PhD, Okumura, Meinoshin, MD, PhD, Kangawa, Kenji, PhD

“…Abstract Background C-type natriuretic peptide (CNP), secreted by vascular endothelial cells, belongs to a family of peptides that includes atrial and brain…”
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Allogenic fetal membrane-derived mesenchymal stem cells contribute to renal repair in experimental glomerulonephritis by Tsuda, Hidetoshi, Yamahara, Kenichi, Ishikane, Shin, Otani, Kentaro, Nakamura, Atsuhiro, Sawai, Kazutomo, Ichimaru, Naotsugu, Sada, Masaharu, Taguchi, Akihiko, Hosoda, Hiroshi, Tsuji, Masahiro, Kawachi, Hiroshi, Horio, Masaru, Isaka, Yoshitaka, Kangawa, Kenji, Takahara, Shiro, Ikeda, Tomoaki

“…Mesenchymal stem cells (MSC) have been reported to be an attractive therapeutic cell source for the treatment of renal diseases. Recently, we reported that…”
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RETRACTED: Atrial natriuretic peptide prevents cancer metastasis through vascular endothelial cells by Nojiri, Takashi, Hosoda, Hiroshi, Tokudome, Takeshi, Miura, Koichi, Ishikane, Shin, Otani, Kentaro, Kishimoto, Ichiro, Shintani, Yasushi, Inoue, Masayoshi, Kimura, Toru, Sawabata, Noriyoshi, Minami, Masato, Nakagiri, Tomoyuki, Funaki, Soichiro, Takeuchi, Yukiyasu, Maeda, Hajime, Kidoya, Hiroyasu, Kiyonari, Hiroshi, Shioi, Go, Arai, Yuji, Hasegawa, Takeshi, Takakura, Nobuyuki, Hori, Megumi, Ohno, Yuko, Miyazato, Mikiya, Mochizuki, Naoki, Okumura, Meinoshin, Kangawa, Kenji

“…Most patients suffering from cancer die of metastatic disease. Surgical removal of solid tumors is performed as an initial attempt to cure patients; however,…”
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Therapeutic Time Window of Cannabidiol Treatment on Delayed Ischemic Damage via High-Mobility Group Box1-Inhibiting Mechanism by Hayakawa, Kazuhide, Irie, Keiichi, Sano, Kazunori, Watanabe, Takuya, Higuchi, Sei, Enoki, Makiko, Nakano, Takafumi, Harada, Kazuhiko, Ishikane, Shin, Ikeda, Tomoaki, Fujioka, Masayuki, Orito, Kensuke, Iwasaki, Katsunori, Mishima, Kenichi, Fujiwara, Michihiro

“…Cannabidiol decreases cerebral infarction and high-mobility group box1 (HMGB1) in plasma in ischemic early phase. However, plasma HMGB1 levels in ischemic…”
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Spatial Memory Impairment Without Apoptosis Induced by the Combination of Beta-Amyloid Oligomers and Cerebral Ischemia Is Related to Decreased Acetylcholine Release in Rats by Watanabe, Takuya, Iwasaki, Katsunori, Ishikane, Shin, Naitou, Tetsuya, Yoshimitsu, Yoshitaka, Yamagata, Norito, Ozdemir, Mehmeto Bülent, Takasaki, Kotaro, Egashira, Nobuaki, Mishima, Kenichi, Fujiwara, Michihiro

“…The purpose of the present study was to examine the effect of beta-amyloid (Aβ ) oligomers, not the fibrils that make up Aβ plaques, on spatial memory and the…”
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Promising small molecule anti-fibrotic agents: Newly developed or repositioned drugs targeting myofibroblast transdifferentiation by Ishikane, Shin, Arioka, Masaki, Takahashi-Yanaga, Fumi

“…[Display omitted] Fibrosis occurs in all organs and tissues except the brain, and its progression leads to dysfunction of affected organs. Fibrosis-induced…”
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