Search Results - "Ishii, Takeshi"

Modulatory Effect of Theaflavins on Apical Sodium-Dependent Bile Acid Transporter (ASBT) Activity by Takashima, Yuki, Ishikawa, Kazuki, Miyawaki, Rina, Ogawa, Mana, Ishii, Takeshi, Misaka, Takumi, Kobayashi, Shoko

“…Inhibiting apical sodium-dependent bile acid transporter (ASBT) has been identified as a potential strategy to reduce plasma cholesterol levels. Thus, in this…”
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cGAS-STING signaling encourages immune cell overcoming of fibroblast barricades in pancreatic cancer by Kabashima, Ayano, Matsuo, Yuki, Ito, Saki, Akiyama, Yoshimitsu, Ishii, Takeshi, Shimada, Shu, Masamune, Atsushi, Tanabe, Minoru, Tanaka, Shinji

“…Immune checkpoint blockade (ICB) treatment improves the prognosis of several types of solid tumors, however, responsiveness to ICB therapy remains low in…”
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The Thioredoxin-1 Inhibitor, PX-12, Suppresses Local Osteosarcoma Progression by Kinoshita, Hideyuki, Shimozato, Osamu, Ishii, Takeshi, Kamoda, Hiroto, Hagiwara, Yoko, Ohtori, Seiji, Yonemoto, Tsukasa

“…Background/Aim: The thioredoxin-1 (Trx-1) inhibitor, PX-12, is active against several cancer types. This study aimed to evaluate its effects on local…”
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Clavicula Pro Humero Reconstruction for Malignant Tumor of the Proximal Humerus in Children and Adults by Kinoshita, Hideyuki, Kamoda, Hiroto, Hagiwara, Yoko, Ishii, Takeshi, Ohtori, Seiji, Yonemoto, Tsukasa

“…The effectiveness of clavicula pro humero (CPH) reconstruction for pediatric proximal humerus sarcoma has been reported in a small number of cases. We aimed to…”
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Identification of a novel target of SETD1A histone methyltransferase and the clinical significance in pancreatic cancer by Ishii, Takeshi, Akiyama, Yoshimitsu, Shimada, Shu, Kabashima, Ayano, Asano, Daisuke, Watanabe, Shuichi, Ishikawa, Yoshiya, Ueda, Hiroki, Akahoshi, Keiichi, Ogawa, Kosuke, Ono, Hiroaki, Kudo, Atsushi, Tanabe, Minoru, Tanaka, Shinji

“…Although histone H3K4 methyltransferase SETD1A is overexpressed in various cancer types, the molecular mechanism underlying its overexpression and its target…”
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Identification of lactate dehydrogenase as a mammalian pyrroloquinoline quinone (PQQ)-binding protein by Akagawa, Mitsugu, Minematsu, Kenji, Shibata, Takahiro, Kondo, Tatsuhiko, Ishii, Takeshi, Uchida, Koji

“…Pyrroloquinoline quinone (PQQ), a redox-active o -quinone, is an important nutrient involved in numerous physiological and biochemical processes in mammals…”
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Clinical analysis of multimodal treatment for localized synovial sarcoma: A multicenter retrospective study by Hagiwara, Yoko, Iwata, Shintaro, Ogura, Koichi, Kawai, Akira, Susa, Michiro, Morioka, Hideo, Hiruma, Toru, Tsuda, Yusuke, Kawano, Hirotaka, Yonemoto, Tsukasa, Ishii, Takeshi, Okazaki, Ken

“…Several prognostic factors for survival in synovial sarcoma have been proposed, but the role of adjuvant chemotherapy and radiotherapy is a matter of debate…”
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Matcha and Its Components Control Angiogenic Potential by IWAI, Ryota, ISHII, Takeshi, FUKUSHIMA, Yoichi, OKAMOTO, Tadashi, ICHIHASHI, Masamitsu, SASAKI, Yasuto, MIZUATNI, Ken-ichi

“…The brain needs the appropriate capillary networks to maintain normal brain function. Since previous studies showed age-related decrease in the cortical…”
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Human Serum Albumin as an Antioxidant in the Oxidation of (−)-Epigallocatechin Gallate: Participation of Reversible Covalent Binding for Interaction and Stabilization by ISHII, Takeshi, ICHIKAWA, Tatsuya, MINODA, Kanako, KUSAKA, Koji, ITO, Sohei, SUZUKI, Yukiko, AKAGAWA, Mitsugu, MOCHIZUKI, Kazuki, GODA, Toshinao, NAKAYAMA, Tsutomu

“…Human serum albumin (HSA) contributes to the stabilization of (−)-epigallocatechin gallate (EGCg) in serum. We characterize in the present study the mechanisms…”
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Effectiveness of Salvage Knee Rotationplasty on Sarcoma Around the Knee in Adolescents and Young Adults by Kinoshita, Hideyuki, Yonemoto, Tsukasa, Kamoda, Hiroto, Hagiwara, Yoko, Tsukanishi, Toshinori, Inoue, Masahiro, Terakawa, Fumihide, Ohtori, Seiji, Ishii, Takeshi

“…This study aimed to investigate the effectiveness of knee rotationplasty (KRP) as salvage surgery for uncontrolled infection and implant failure of total knee…”
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Covalent modification of proteins by green tea polyphenol (–)-epigallocatechin-3-gallate through autoxidation by Ishii, Takeshi, Mori, Taiki, Tanaka, Tomoko, Mizuno, Daisuke, Yamaji, Ryoichi, Kumazawa, Shigenori, Nakayama, Tsutomu, Akagawa, Mitsugu

“…Green tea polyphenol (–)-epigallocatechin-3-gallate (EGCG) has various beneficial properties including chemopreventive, anticarcinogenic, and antioxidant…”
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A Single Oral Administration of Theaflavins Increases Energy Expenditure and the Expression of Metabolic Genes by Kudo, Naoto, Arai, Yasunori, Suhara, Yoshitomo, Ishii, Takeshi, Nakayama, Tsutomu, Osakabe, Naomi

“…Theaflavins are polyphenols found in black tea, whose physiological activities are not well understood. This study on mice evaluated the influence of a single…”
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Circulating MicroRNA-92b-3p as a Novel Biomarker for Monitoring of Synovial Sarcoma by Uotani, Koji, Fujiwara, Tomohiro, Yoshida, Aki, Iwata, Shintaro, Morita, Takuya, Kiyono, Masahiro, Yokoo, Suguru, Kunisada, Toshiyuki, Takeda, Ken, Hasei, Joe, Numoto, Kunihiko, Nezu, Yutaka, Yonemoto, Tsukasa, Ishii, Takeshi, Kawai, Akira, Ochiya, Takahiro, Ozaki, Toshifumi

“…The lack of useful biomarkers is a crucial problem for patients with soft tissue sarcomas (STSs). Emerging evidence has suggested that circulating microRNAs…”
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Optimal surgical margin for infiltrative soft tissue sarcomas: Assessing the efficacy of excising beyond the infiltration by Iwata, Shintaro, Araki, Akinobu, Funatsu, Hiroyuki, Yonemoto, Tsukasa, Kamoda, Hiroto, Itami, Makiko, Ishii, Takeshi

“…Background Tumor infiltration in soft tissue sarcoma (STS) is known to correlate with an inadequate surgical margin and poor local control. This study aims to…”
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Poor Efficacy of Postoperative Radiotherapy in Infiltrative High-grade Soft Tissue Sarcomas by Kinoshita, Hideyuki, Ishii, Takeshi, Kamoda, Hiroto, Hagiwara, Yoko, Tsukanishi, Toshinori, Inoue, Masahiro, Ueta, Toru, Ohtori, Seiji, Yonemoto, Tsukasa

“…Background/Aim: We aimed to investigate the effectiveness of postoperative radiotherapy (RT) on local recurrence-free survival (LRFS) in high-grade…”
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Comparison of the sympathetic stimulatory abilities of B-type procyanidins based on induction of uncoupling protein-1 in brown adipose tissue (BAT) and increased plasma catecholamine (CA) in mice by Nakagawa, Yuta, Ishimura, Kana, Oya, Satomi, Kamino, Masaki, Fujii, Yasuyuki, Nanba, Fumio, Toda, Toshiya, Ishii, Takeshi, Adachi, Takahiro, Suhara, Yoshitomo, Osakabe, Naomi

“…We previously found that elevated energy expenditure following a single oral dose of flavan 3-ols (FL), a mixture of catechins and B type procyanidins, is…”
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Skeletal muscle depletion during chemotherapy has a large impact on physical function in elderly Japanese patients with advanced non-small-cell lung cancer by Naito, Tateaki, Okayama, Taro, Aoyama, Takashi, Ohashi, Takuya, Masuda, Yoshiyuki, Kimura, Madoka, Shiozaki, Hitomi, Murakami, Haruyasu, Kenmotsu, Hirotsugu, Taira, Tetsuhiko, Ono, Akira, Wakuda, Kazushige, Imai, Hisao, Oyakawa, Takuya, Ishii, Takeshi, Omori, Shota, Nakashima, Kazuhisa, Endo, Masahiro, Omae, Katsuhiro, Mori, Keita, Yamamoto, Nobuyuki, Tanuma, Akira, Takahashi, Toshiaki

“…Elderly patient with advanced cancer is one of the most vulnerable populations. Skeletal muscle depletion during chemotherapy may have substantial impact on…”
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Evaluation of urinary tissue inhibitor of metalloproteinase-2 in acute kidney injury: a prospective observational study by Yamashita, Tetsushi, Doi, Kent, Hamasaki, Yoshifumi, Matsubara, Takehiro, Ishii, Takeshi, Yahagi, Naoki, Nangaku, Masaomi, Noiri, Eisei

“…Tissue inhibitor of metalloproteinase-2 (TIMP-2) is an emerging acute kidney injury (AKI) biomarker. We evaluated the performance of urinary TIMP-2 in an adult…”
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Prognostic Factors in Elderly Osteosarcoma Patients: A Multi-institutional Retrospective Study of 86 Cases by Iwata, Shintaro, Ishii, Takeshi, Kawai, Akira, Hiruma, Toru, Yonemoto, Tsukasa, Kamoda, Hiroto, Asano, Naofumi, Takeyama, Masanobu

“…Background The occurrence of osteosarcoma in elderly patients has recently been increasing, and the outcome is poor. This multi-institutional retrospective…”
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Activation of transient receptor potential ankyrin 1 by quercetin and its analogs by Nakamura, Toshiyuki, Miyoshi, Noriyuki, Ishii, Takeshi, Nishikawa, Miyu, Ikushiro, Shinichi, Watanabe, Tatsuo

“…The agonistic activity of quercetin and its analogs towards the transient receptor potential ankyrin 1 (TRPA1) has been experimentally investigated. The human…”
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