Search Results - "Ishii, Norihiro"

Mac-2 binding protein glycan isomer (M2BPGi) is a new serum biomarker for assessing liver fibrosis: more than a biomarker of liver fibrosis by Shirabe, Ken, Bekki, Yuki, Gantumur, Dolgormaa, Araki, Kenichiro, Ishii, Norihiro, Kuno, Atsushi, Narimatsu, Hisashi, Mizokami, Masashi

“…Assessing liver fibrosis is important for predicting the efficacy of antiviral therapy and patient prognosis. Liver biopsy is the gold standard for diagnosing…”
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Nintedanib inhibits intrahepatic cholangiocarcinoma aggressiveness via suppression of cytokines extracted from activated cancer-associated fibroblasts by Yamanaka, Takahiro, Harimoto, Norifumi, Yokobori, Takehiko, Muranushi, Ryo, Hoshino, Kouki, Hagiwara, Kei, Gantumur, Dolgormaa, Handa, Tadashi, Ishii, Norihiro, Tsukagoshi, Mariko, Igarashi, Takamichi, Tanaka, Hiroshi, Watanabe, Akira, Kubo, Norio, Araki, Kenichiro, Shirabe, Ken

“…Background Intrahepatic cholangiocarcinoma (ICC) is a malignancy that is challenging to treat. Fibroblasts in ICC tissues have been identified as…”
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Impact of preoperative nutritional support and rehabilitation therapy in patients undergoing pancreaticoduodenectomy by Tsukagoshi, Mariko, Harimoto, Norifumi, Araki, Kenichiro, Kubo, Norio, Watanabe, Akira, Igarashi, Takamichi, Ishii, Norihiro, Yamanaka, Takahiro, Hagiwara, Kei, Hoshino, Kouki, Muranushi, Ryo, Yajima, Toshiki, Wada, Naoki, Shirabe, Ken

“…Background Sarcopenia is closely associated with morbidity after pancreatic surgery. We investigated the impact of preoperative nutritional support and…”
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Mac-2-binding protein glycan isomer enhances the aggressiveness of hepatocellular carcinoma by activating mTOR signaling by Dolgormaa, Gantumur, Harimoto, Norifumi, Ishii, Norihiro, Yamanaka, Takahiro, Hagiwara, Kei, Tsukagoshi, Mariko, Igarashi, Takamichi, Watanabe, Akira, Kubo, Norio, Araki, Kenichiro, Handa, Tadashi, Yokobori, Takehiko, Oyama, Tetsunari, Kuwano, Hiroyuki, Shirabe, Ken

“…Background Wisteria floribunda agglutinin (WFA) + Mac-2-binding protein (M2BPGi) is a novel serum marker for liver fibrosis. Although an elevated serum level…”
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Conophylline suppresses pancreatic cancer desmoplasia and cancer‐promoting cytokines produced by cancer‐associated fibroblasts by Ishii, Norihiro, Araki, Kenichiro, Yokobori, Takehiko, Hagiwara, Kei, Gantumur, Dorgormaa, Yamanaka, Takahiro, Handa, Tadashi, Tsukagoshi, Mariko, Igarashi, Takamichi, Watanabe, Akira, Kubo, Norio, Harimoto, Norifumi, Masamune, Atsushi, Umezawa, Kazuo, Kuwano, Hiroyuki, Shirabe, Ken

“…Despite recent advances in cancer treatment, pancreatic cancer is a highly malignant tumor type with a dismal prognosis and it is characterized by dense…”
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A new liver regeneration molecular mechanism involving hepatic stellate cells, Kupffer cells, and glucose‐regulated protein 78 as a new hepatotrophic factor by Hagiwara, Kei, Harimoto, Norifumi, Yamanaka, Takahiro, Ishii, Norihiro, Yokobori, Takehiko, Tsukagoshi, Mariko, Watanabe, Akira, Araki, Kenichiro, Yoshizumi, Tomoharu, Shirabe, Ken

“…Background/Purpose To overcome liver failure, we focused on liver regeneration mechanisms by the activation of hepatic stellate cells (HSCs) and Kupffer cells…”
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Diffusion-Weighted MRI Predicts Lymph Node Metastasis and Tumor Aggressiveness in Resectable Pancreatic Neuroendocrine Tumors by Harimoto, Norifumi, Araki, Kenichiro, Hoshino, Kouki, Muranushi, Ryo, Hagiwara, Kei, Ishii, Norihiro, Tsukagoshi, Mariko, Igarashi, Takamichi, Watanabe, Akira, Kubo, Norio, Tomonaga, Hiroyasu, Higuchi, Tetsuya, Tsushima, Yoshito, Ikota, Hayato, Shirabe, Ken

“…Objectives The aim of this study was to identify whether diffusion-weighted magnetic resonance imaging (DW-MRI) can predict the malignant behavior of…”
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Conophylline Inhibits Hepatocellular Carcinoma by Inhibiting Activated Cancer-associated Fibroblasts Through Suppression of G Protein-coupled Receptor 68 by Yamanaka, Takahiro, Harimoto, Norifumi, Yokobori, Takehiko, Muranushi, Ryo, Hoshino, Kouki, Hagiwara, Kei, Gantumur, Dolgormaa, Handa, Tadashi, Ishii, Norihiro, Tsukagoshi, Mariko, Igarashi, Takamichi, Watanabe, Akira, Kubo, Norio, Araki, Kenichiro, Umezawa, Kazuo, Shirabe, Ken

“…Treatment of hepatocellular carcinoma (HCC) is currently challenging. Cancer-associated fibroblasts (CAFs) promote the malignancy of HCC cells via production…”
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The ratio of creatinine and cystatin C estimated glomerular filtration rates as a surrogate marker in patients with hepatocellular carcinoma undergoing hepatic resection by Harimoto, Norifumi, Araki, Kenichiro, Yamanaka, Takahiro, Hagiwara, Kei, Ishii, Norihiro, Tsukagoshi, Mariko, Watanabe, Akira, Takizawa, Makiko, Yokobori, Takehiko, Shirabe, Ken

“…Background The ratio of creatinine and cystatin C estimated glomerular filtration rates (eGFRcre/eGFRcys) is significantly positively correlated with…”
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High membrane expression of CMTM6 in hepatocellular carcinoma is associated with tumor recurrence by Muranushi, Ryo, Araki, Kenichiro, Yokobori, Takehiko, Chingunjav, Batbayar, Hoshino, Kouki, Dolgormaa, Gantumur, Hagiwara, Kei, Yamanaka, Takahiro, Ishii, Norihiro, Tsukagoshi, Mariko, Igarashi, Takamichi, Watanabe, Akira, Kubo, Norio, Harimoto, Norifumi, Shimoda, Yuki, Sano, Rie, Oyama, Tetsunari, Saeki, Hiroshi, Shirabe, Ken

“…CKLF‐like MARVEL transmembrane domain–containing protein 6 (CMTM6) maintains membrane PD‐L1 expression by controlling its endosomal recycling. However, in…”
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RNF31 promotes proliferation and invasion of hepatocellular carcinoma via nuclear factor kappaB activation by Hoshino, Kouki, Nakazawa, Seshiru, Yokobori, Takehiko, Hagiwara, Kei, Ishii, Norihiro, Tsukagoshi, Mariko, Igarashi, Takamichi, Araki, Kenichiro, Harimoto, Norifumi, Tokunaga, Fuminori, Shirabe, Ken

“…RNF31 is a multifunctional RING finger protein implicated in various inflammatory diseases and cancers. It functions as a core component of the linear…”
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FDG-PET reflects tumor viability on SUV in colorectal cancer liver metastasis by Watanabe, Akira, Harimoto, Norifumi, Yokobori, Takehiko, Araki, Kenichiro, Kubo, Norio, Igarashi, Takamichi, Tsukagoshi, Mariko, Ishii, Norihiro, Yamanaka, Takahiro, Handa, Tadashi, Oyama, Tetsunari, Higuchi, Tetsuya, Shirabe, Ken

“…Background Liver resection is the most effective procedure for colorectal cancer liver metastasis (CRLM); however, early recurrence is an important problem…”
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A prospective study of sequential hepatic vein embolization after portal vein embolization in patients scheduled for right‐sided major hepatectomy: Results of feasibility and surgical strategy using functional liver assessment by Araki, Kenichiro, Shibuya, Kei, Harimoto, Norifumi, Watanabe, Akira, Tsukagoshi, Mariko, Ishii, Norihiro, Ikota, Hayato, Yokobori, Takehiko, Tsushima, Yoshito, Shirabe, Ken

“…Background Hepatic vein embolization (HVE) added to portal vein embolization (PVE) can further increase future remnant liver volume (FRLV) compared with PVE…”
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Overexpression of natural killer group 2 member D ligands predicts favorable prognosis in cholangiocarcinoma by Tsukagoshi, Mariko, Wada, Satoshi, Yokobori, Takehiko, Altan, Bolag, Ishii, Norihiro, Watanabe, Akira, Kubo, Norio, Saito, Fumiyoshi, Araki, Kenichiro, Suzuki, Hideki, Hosouchi, Yasuo, Kuwano, Hiroyuki

“…The natural killer group 2 member D (NKG2D) receptor and its ligands are important mediators of immune responses to tumors. NKG2D ligands are overexpressed in…”
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Significance of zinc deficiency in patients with hepatocellular carcinoma undergoing hepatic resection by Harimoto, Norifumi, Araki, Kenichiro, Muranushi, Ryo, Hoshino, Kouki, Yamanaka, Takahiro, Hagiwara, Kei, Ishii, Norihiro, Tsukagoshi, Mariko, Watanabe, Akira, Shirabe, Ken

“…Aim Few reported studies examine the relationship between zinc (Zn) deficiency and short‐ and long‐term outcomes in patients with hepatocellular carcinoma…”
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Abdominal aortic calcification volume (AACV) is a predictive factor for postoperative complications associated with biliary tract cancer by Watanabe, Akira, Harimoto, Norifumi, Araki, Kenichiro, Tsukagoshi, Mariko, Ishii, Norihiro, Hagiwara, Kei, Yamanaka, Takahiro, Hoshino, Kouki, Muranushi, Ryo, Shirabe, Ken

“…Purpose Curative surgical treatment of biliary tract cancer is highly invasive and involves postoperative complications. Abdominal aortic calcification is a…”
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High Co-expression of Large Tenascin C Splice Variants in Stromal Tissue and Annexin A2 in Cancer Cell Membranes is Associated with Poor Prognosis in Pancreatic Cancer by Hagiwara, Kei, Harimoto, Norifumi, Yokobori, Takehiko, Muranushi, Ryo, Hoshino, Kouki, Gantumur, Dorgormaa, Yamanaka, Takahiro, Ishii, Norihiro, Tsukagoshi, Mariko, Igarashi, Takamichi, Tanaka, Hiroshi, Watanabe, Akira, Kubo, Norio, Araki, Kenichiro, Hosouchi, Yasuo, Shirabe, Ken

“…Background Pancreatic cancer tissue contains abundant stromal components, including extracellular matrix proteins such as tenascin C (TNC), which exists as…”
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Albumin–Indocyanine Green Evaluation (ALICE) grade predicts bile leakage after hepatic resection by Harimoto, Norifumi, Muranushi, Ryo, Hoshino, Kouki, Yamanaka, Takahiro, Hagiwara, Kei, Ishii, Norihiro, Tsukagoshi, Mariko, Igarashi, Takamichi, Watanabe, Akira, Kubo, Norio, Araki, Kenichiro, Shirabe, Ken

“…Purpose We investigated the predictors of bile leakage after hepatic resection. Methods The data of 270 consecutive patients who underwent curative hepatic…”
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Lower Geriatric Nutritional Risk Index and Prognostic Nutritional Index Predict Postoperative Prognosis in Patients with Hepatocellular Carcinoma by Tsukagoshi, Mariko, Araki, Kenichiro, Igarashi, Takamichi, Ishii, Norihiro, Kawai, Shunsuke, Hagiwara, Kei, Hoshino, Kouki, Seki, Takaomi, Okuyama, Takayuki, Fukushima, Ryosuke, Harimoto, Norifumi, Shirabe, Ken

“…Increasing evidence suggests that nutritional indices, including the geriatric nutritional risk index (GNRI) and prognostic nutritional index (PNI), are…”
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D-dimer predicts postoperative recurrence and prognosis in patients with liver metastasis of colorectal cancer by Watanabe, Akira, Araki, Kenichiro, Harimoto, Norihumi, Kubo, Norio, Igarashi, Takamichi, Ishii, Norihiro, Yamanaka, Takahiro, Hagiwara, Kei, Kuwano, Hiroyuki, Shirabe, Ken

“…Background Colorectal cancer is common, and its incidence is increasing throughout the world. The liver is a major metastatic site, and colorectal liver…”
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