Search Results - "Ishiguro, Takako"

Evaluation for Blood Concentration and Efficacy/Safety of Continuous Administration of Thiamylal in Children by Hirata, Kenshiro, Obara, Takafumi, Ikeda, Tokunori, Watanabe, Hiroshi, Fujita, Issei, Furusho, Hirokazu, Ishiguro, Takako, Jingami, Sachiko, Maruyama, Toru, Hirai, Katsuki, Miyamura, Shigeyuki

“…Thiamylal exerts excellent sedative effects. However, it is not routinely used because of its serious adverse effects. This study aimed to clarify the target…”
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The Use of Enteric Capsules for Releasing a Fragrance over an Extended Period of Time by Ishiguro, Takako, Sakata, Yukoh, Arima, Hidetoshi, Iohara, Daisuke, Anraku, Makoto, Uekama, Kaneto, Hirayama, Fumitoshi

“…A system for releasing a fragrance, citral (CR) over an extended period of time using three types of enteric capsules is reported. The L- and M-type capsules…”
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Pharmacokinetic properties of a novel inosine analog, 4'-cyano-2'-deoxyinosine, after oral administration in rats by Hashimoto, Mai, Taguchi, Kazuaki, Ishiguro, Takako, Kohgo, Satoru, Imoto, Shuhei, Yamasaki, Keishi, Mitsuya, Hiroaki, Otagiri, Masaki

“…4'-cyano-2'-deoxyinosine (SK14-061a), a novel nucleoside analog based on inosine, has antiviral activity against the human immunodeficiency virus type 1 that…”
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Tyrosine411 and Arginine410 of Human Serum Albumin Play an Important Role in the Binding of Sodium 4-Phenylbutyrate to Site II by Enokida, Taisuke, Yamasaki, Keishi, Okamoto, Yuko, Taguchi, Kazuaki, Ishiguro, Takako, Maruyama, Toru, Seo, Hakaru, Otagiri, Masaki

“…Sodium 4-phenylbutyrate (PB) has many pharmacological activities; therefore extending its clinical use to the treatment of a wider variety of diseases would be…”
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Pharmacokinetics studies of 4′‐cyano‐2′‐deoxyguanosine, a potent inhibitor of the hepatitis B virus, in rats by Hashimoto, Mai, Taguchi, Kazuaki, Ishiguro, Takako, Kohgo, Satoru, Imoto, Shuhei, Yamasaki, Keishi, Mitsuya, Hiroaki, Otagiri, Masaki

“…Objectives 4′‐cyano‐2′‐deoxyguanosine (CdG), a novel nucleoside analogue, has a high degree of antiviral activity against the chronic hepatitis B virus (HBV)…”
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Surface-Deacetylated Chitin Nano-Fiber/Hyaluronic Acid Composites as Potential Antioxidative Compounds for Use in Extended-Release Matrix Tablets by Anraku, Makoto, Tabuchi, Ryo, Ifuku, Shinsuke, Ishiguro, Takako, Iohara, Daisuke, Hirayama, Fumitoshi

“…In this study, we examined a possible use of a surface-deacetylated chitin nano-fiber (SDCH-NF) and hyaluronic acid (HA) interpolymer complex (IPC) tablet as a…”
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In vitro transdermal permeation behavior of isosorbide dinitrate in the absence and presence of 2-hydroxypropyl-β-cyclodextrin: solutions and suspensions by Zao, Katsutoshi, Ishiguro, Takako, Iohara, Daisuke, Anraku, Makoto, Seo, Hakaru, Irie, Tetsumi, Uekama, Kaneto, Hirayama, Fumitoshi

“…Interactions of a vasodilator, isosorbide dinitrate (ISDN), with the parent α-, β- and γ-cyclodextrins (α-, β- and γ-CDs) and 2-hydroxypropyl-α- and -β- and…”
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Prominent Inhibitory Effect of 2-Hydroxybutyl-β-cyclodextrin on Solution-mediated Polymorphic Transition of Chlorpropamide by Ishiguro, Takako, Hirayama, Fumitoshi, Iohara, Daisuke, Uekama, Kaneto

“…The effects of cyclodextrins on crystallization of chlorpropamide from aqueous solutions were investigated. Parent α-, β-, and γ-cyclodextrins and…”
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Release control of fragrances by complexation with β-cyclodextrin and its derivatives by Ishiguro, Takako, Sakata, Yukichi, Arima, Hidetoshi, Iohara, Daisuke, Anraku, Makoto, Uekama, Kaneto, Hirayama, Fumitoshi

“…The release control of fragrances, benzyl acetate (BA), citral (CR), linalool (LL), citronellol (CL) and linalyl acetate (LA), was conducted using…”
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Surface-deacetylated chitin nanofibers reinforced with a sulfobutyl ether β-cyclodextrin gel loaded with prednisolone as potential therapy for inflammatory bowel disease by Tabuchi, Ryo, Anraku, Makoto, Iohara, Daisuke, Ishiguro, Takako, Ifuku, Shinsuke, Nagae, Tomone, Uekama, Kaneto, Okazaki, Shoko, Takeshita, Keizo, Otagiri, Masaki, Hirayama, Fumitoshi

“…•The effect of NFs-CDs gel has the potential for use for the controlled release of PD.•The effect of NFs-CDs gel resulted in reduction of colitis symptoms and…”
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Crystallization and polymorphic transitions of chlorpropamide in aqueous 2-hydroxybutyl-β-cyclodextrin solution by Ishiguro, Takako, Hirayama, Fumitoshi, Iohara, Daisuke, Arima, Hidetoshi, Uekama, Kaneto

“…Effects of cyclodextrins on crystallization of chlorpropamide and the polymorphic transition mechanism of the drug in aqueous solution were investigated. In…”
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Some pharmaceutical and inclusion properties of 2-hydroxybutyl-β-cyclodextrin derivative by Ishiguro, Takako, Morishita, Eri, Iohara, Daisuke, Hirayama, Fumitoshi, Wada, Koki, Motoyama, Keiichi, Arima, Hidetoshi, Uekama, Kaneto

“…2-Hydroxybutyl-β-cyclodextrins (HB-β-CyDs) with different degrees of substitution (D.S.) were prepared and their physicochemical and biological properties and…”
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Reduction of bitterness of antihistaminic drugs by complexation with β-cyclodextrins by Ono, Nao, Miyamoto, Yuji, Ishiguro, Takako, Motoyama, Keiichi, Hirayama, Fumitoshi, Iohara, Daisuke, Seo, Hakaru, Tsuruta, Satoshi, Arima, Hidetoshi, Uekama, Kaneto

“…Reduction of bitterness of antihistaminic drugs by cyclodextrin (CyD) complexation was examined. The stability constant (Kc) of the 1:1 CyD inclusion complexes…”
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Cyclodextrins improve oral absorption of a novel factor Xa inhibitor by interfering with interaction between the drug and bile acids in rats by Fujii, Yoshimine, Takahashi, Masayuki, Ishiguro, Takako, Sakuma, Shinji, Uekama, Kaneto, Irie, Tetsumi

“…Objectives Poor oral absorption of a factor Xa inhibitor, DX‐9065, is partly due to the interaction with bile acids in the gastrointestinal tract. The aim of…”
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Preparation of amorphous indomethacin from aqueous 2,6-di- O-methyl-β-cyclodextrin solution by Iohara, Daisuke, Hirayama, Fumitoshi, Ishiguro, Takako, Arima, Hidetoshi, Uekama, Kaneto

“…Indomethacin precipitated exclusively in an amorphous form from aqueous 2,6-di- O-methyl-β-cyclodextrin solutions, whereas it precipitated in Form V polymorph…”
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Enhancement of the aqueous solubility and masking the bitter taste of famotidine using drug/SBE-beta-CyD/povidone K30 complexation approach by Mady, Fatma M, Abou-Taleb, Ahmed E, Khaled, Khaled A, Yamasaki, Keishi, Iohara, Daisuke, Ishiguro, Takako, Hirayama, Fumitoshi, Uekama, Kaneto, Otagiri, Masaki

“…The objective of the present study was to evaluate the potential of ternary system (comprised of famotidine, beta-cyclodextrin (beta-CyD) or its derivatives…”
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Improvement of some physicochemical properties of arundic acid, (R)-(−)-2-propyloctanonic acid, by complexation with hydrophilic cyclodextrins by Miyamoto, Yuji, Nakahara, Mai, Motoyama, Keiichi, Ishiguro, Takako, Oda, Yoshiki, Yamanoi, Takashi, Okamoto, Ichiro, Yagi, Akira, Nishimura, Hidekatsu, Hirayama, Fumitoshi, Uekama, Kaneto, Arima, Hidetoshi

“…Arundic acid, (R)-(−)-2-propyloctanonic acid, is a novel neurological agent for intractable neurodegenerative diseases. However, arundic acid, an oily drug,…”
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Prominent Inhibitory Effect of 2-Hydroxybutyl-[beta]-cyclodextrin on Solution-mediated Polymorphic Transition of Chlorpropamide by Ishiguro, Takako, Hirayama, Fumitoshi, Iohara, Daisuke, Uekama, Kaneto

“…The effects of cyclodextrins on crystallization of chlorpropamide from aqueous solutions were investigated. Parent α-, β-, and γ-cyclodextrins and…”
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