Search Results - "Isenoumi, Kazuyuki"
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Contribution of mitogen-activated protein kinases to NMDA-induced neurotoxicity in the rat retina
Published in Brain research (24-05-2005)“…We examined the contributions of the mitogen-activated protein kinases (MAPKs) family [extracellular signal-regulated kinase (ERK), p38 kinase (p38), and c-Jun…”
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Neuroprotective effect of atrial natriuretic peptide against NMDA-induced neurotoxicity in the rat retina
Published in Brain research (03-02-2006)“…Atrial natriuretic peptide (ANP) can regulate aqueous humor production in the eye and has recently been suggested to play some functional roles in the retina…”
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3
N-Methyl-D-aspartate Induces Phosphorylation of cAMP Response Element (CRE)-Binding Protein and Increases DNA-Binding Activity of CRE in Rat Retina
Published in Journal of Pharmacological Sciences (2004)“…The aim of this study was to investigate whether an excitotoxic concentration of N-methyl-D-aspartate (NMDA) increases the expression of the phosphorylated…”
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4
Nipradilol induces vasodilation of canine isolated posterior ciliary artery via stimulation of the guanylyl cyclase-cGMP pathway
Published in Life sciences (1973) (26-07-2002)“…We examined the effect of nipradilol on contraction of the posterior ciliary artery induced by high potassium or norepinephrine and on cyclic GMP (cGMP) levels…”
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Nuclear factor-kappa B p65 in NMDA-induced retinal neurotoxicity
Published in Brain research. Molecular brain research. (24-11-2004)“…Transcription factors of the nuclear factor-kappa B (NF-κB)/Rel family may be involved in neuronal cell death or survival. We examined the role of NF-κB p65 in…”
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Involvement of RhoA and possible neuroprotective effect of fasudil, a Rho kinase inhibitor, in NMDA-induced neurotoxicity in the rat retina
Published in Brain research (20-08-2004)“…RhoA, a key protein involved in cytoskeleton regulation modulating neurogenesis and neural plasticity, has been implicated in a variety of cellular functions…”
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Neuroprotective effect of nitric oxide against NMDA-induced neurotoxicity in the rat retina is associated with tyrosine hydroxylase expression
Published in Brain research (04-07-2003)“…N-Methyl- d-aspartate (NMDA) may affect dopaminergic cells, which contain tyrosine hydroxylase (TH), the rate-limiting enzyme in dopamine synthesis. To clarify…”
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