Search Results - "Isayama, Keishiro"
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Standardization of an LNA-based TaqMan assay qPCR analysis for Aspiculuris tetraptera DNA in mouse faeces
Published in BMC microbiology (07-12-2020)“…Aspiculuris tetraptera, as a parasitic pinworm, is most frequently detected in laboratory mice, and transmission is mediated by the eggs contained in the…”
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REV-ERBα Inhibits the PTGS2 Expression in Bovine Uterus Endometrium Stromal and Epithelial Cells Exposed to Ovarian Steroids
Published in Journal of Reproduction and Development (2014)“…The nuclear receptor REV-ERBα (encoded by NR1D1) has a critical role in metabolism and physiology as well as circadian rhythm. Here, we investigated the…”
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Bardoxolone methyl prevents metabolic dysfunction‐associated steatohepatitis by inhibiting macrophage infiltration
Published in British journal of pharmacology (01-08-2024)“…Background and Purpose Bardoxolone methyl (2‐cyano‐3,12‐dioxooleana‐1,9(11)‐dien‐28‐oic acid methyl ester, CDDO‐Me) is a potent activator of nuclear factor…”
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A novel somatic mutation of SIN3A detected in breast cancer by whole-exome sequencing enhances cell proliferation through ERα expression
Published in Scientific reports (30-10-2018)“…Breast cancer is the most frequent tumor in women, and in nearly two-thirds of cases, the tumors express estrogen receptor α (ERα, encoded by ESR1 ). Here, we…”
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Inhibitory role of REV-ERBα in the expression of bone morphogenetic protein gene family in rat uterus endometrium stromal cells
Published in American Journal of Physiology: Cell Physiology (01-04-2015)“…Uterus circadian rhythms have been implicated in the gestation processes of mammals through entraining of the clock proteins to numerous downstream genes. Bone…”
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Removal of Rev-erbα inhibition contributes to the prostaglandin G/H synthase 2 expression in rat endometrial stromal cells
Published in American journal of physiology: endocrinology and metabolism (15-04-2015)“…The rhythmic expression of clock genes in the uterus is attenuated during decidualization. This study focused on Ptgs2, which is essential for decidualization,…”
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Integration of the nuclear receptor REV-ERBα linked with circadian oscillators in the expressions of Alas1, Ppargc1a, and Il6 genes in rat granulosa cells
Published in Chronobiology international (01-07-2015)“…The nuclear receptor REV-ERBα links circadian rhythms and numerous physiological processes, but its physiological role in ovaries remains largely unknown. The…”
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The nuclear receptor REV‐ERBα represses the transcription of growth/differentiation factor 10 and 15 genes in rat endometrium stromal cells
Published in Physiological reports (01-01-2016)“…Cellular oscillators in the uterus play critical roles in the gestation processes of mammals through entraining of the clock proteins to numerous downstream…”
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Improvement of the cellular quality of cryopreserved bovine blastocysts accompanied by enhancement of the ATP-binding cassette sub-family B member 1 expression
Published in Reproductive toxicology (Elmsford, N.Y.) (01-01-2013)“…► ABCB1 is expressed in the bovine blastocysts. ► The expression of ABCB1 in bovine blastocysts is highly induced by forskolin and rifampicin. ► The blastocyst…”
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Profiling of circadian genes expressed in the uterus endometrial stromal cells of pregnant rats as revealed by DNA microarray coupled with RNA interference
Published in Frontiers in endocrinology (Lausanne) (2013)“…The peripheral circadian oscillator plays an essential role in synchronizing local physiology to operate in a circadian manner via regulation of the expression…”
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