Search Results - "Isas, Jose M."

Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers by Luibl, Volker, Isas, Jose M, Kayed, Rakez, Glabe, Charles G, Langen, Ralf, Chen, Jeannie

“…Protein misfolding and aggregation are thought to underlie the pathogenesis of many amyloid diseases, such as Alzheimer and Parkinson diseases, whereby a…”
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Structural Mechanisms of Mutant Huntingtin Aggregation Suppression by the Synthetic Chaperonin-like CCT5 Complex Explained by Cryoelectron Tomography by Darrow, Michele C., Sergeeva, Oksana A., Isas, Jose M., Galaz-Montoya, Jesús G., King, Jonathan A., Langen, Ralf, Schmid, Michael F., Chiu, Wah

“…Huntington disease, a neurodegenerative disorder characterized by functional deficits and loss of striatal neurons, is linked to an expanded and unstable CAG…”
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Quantifying Membrane Curvature Generation of Drosophila Amphiphysin N-BAR Domains by Heinrich, Michael C, Capraro, Benjamin R, Tian, Aiwei, Isas, Jose M, Langen, Ralf, Baumgart, Tobias

“…Biological membrane functions are coupled to membrane curvature, the regulation of which often involves membrane-associated proteins. The membrane-binding…”
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LDL protein nitration: Implication for LDL protein unfolding by Hamilton, Ryan T., Asatryan, Liana, Nilsen, Jon T., Isas, Jose M., Gallaher, Timothy K., Sawamura, Tatsuya, Hsiai, Tzung K.

“…Oxidatively- or enzymatically-modified low-density lipoprotein (LDL) is intimately involved in the initiation and progression of atherosclerosis. The in vivo…”
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