Search Results - "Isaeva, Olena"
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1
Keratinocyte PIEZO1 modulates cutaneous mechanosensation
Published in eLife (02-09-2022)“…Epidermal keratinocytes mediate touch sensation by detecting and encoding tactile information to sensory neurons. However, the specific mechanotransducers that…”
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2
Spinal muscular atrophy-like phenotype in a mouse model of acid ceramidase deficiency
Published in Communications biology (25-05-2023)“…Mutations in ASAH1 have been linked to two allegedly distinct disorders: Farber disease (FD) and spinal muscular atrophy with progressive myoclonic epilepsy…”
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3
Abstract MP35: Pharmacological Inhibition And Knockout Of K ir 7.1 Does Not Affect The Development Of Salt-Sensitive Hypertension In The Dahl SS Rat
Published in Hypertension (Dallas, Tex. 1979) (01-09-2021)“…Abstract only Ion channels play a vital role in the kidney’s ability to maintain electrolyte homeostasis, and mutations of certain inwardly rectifying K +…”
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4
Abstract P245: Activation Of Protease-activated Receptors 1 Leads To Structural Changes In Immortalized Cultured Human Podocytes
Published in Hypertension (Dallas, Tex. 1979) (01-09-2021)“…Previous studies have suggested that activation of the protease-activated receptors (PAR) exacerbates the development of diabetic nephropathy. PARs are…”
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5
Abstract MP35: Pharmacological Inhibition And Knockout Of Kir7.1 Does Not Affect The Development Of Salt-Sensitive Hypertension In The Dahl SS Rat
Published in Hypertension (Dallas, Tex. 1979) (01-09-2021)“…Ion channels play a vital role in the kidney’s ability to maintain electrolyte homeostasis, and mutations of certain inwardly rectifying K+ channels (Kir) have…”
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6
Abstract P244: Tubular Sites Of Mtorc2 Inhibition Of Sodium Transport In Dahl Salt-sensitive Rats
Published in Hypertension (Dallas, Tex. 1979) (01-09-2022)“…Abstract only Background: There is evidence that the mTOR signaling pathway plays an important role in salt induced hypertension in the Dahl salt-sensitive…”
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7
Sickle cell disease iPSC-derived sensory neurons exhibit increased excitability and sensitization to patient plasma
Published in Blood (16-05-2024)“…•SCD stem cell–derived sensory neurons (iSNs) exhibit pronounced sensitization to electrical stimulation.•SCD plasma sensitizes SCD iSNs to transient receptor…”
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