Search Results - "Isabelle Briaud"

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  1. 1
    Lipotoxicity of the Pancreatic β-Cell Is Associated With Glucose-Dependent Esterification of Fatty Acids Into Neutral Lipids

    Lipotoxicity of the Pancreatic β-Cell Is Associated With Glucose-Dependent Esterification of Fatty Acids Into Neutral Lipids by BRIAUD, Isabelle, HARMON, Jamie S, KELPE, Cynthia L, SEGU, Venkatesh Babu G, POITOUT, Vincent

    Published in Diabetes (New York, N.Y.) (01-02-2001)
    “…Lipotoxicity of the Pancreatic β-Cell Is Associated With Glucose-Dependent Esterification of Fatty Acids Into Neutral Lipids Isabelle Briaud , Jamie S. Harmon…”
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  2. 2
    Differential Effects of Hyperlipidemia on Insulin Secretion in Islets of Langerhans From Hyperglycemic Versus Normoglycemic Rats

    Differential Effects of Hyperlipidemia on Insulin Secretion in Islets of Langerhans From Hyperglycemic Versus Normoglycemic Rats by BRIAUD, Isabelle, KELPE, Cynthia L, JOHNSON, Lisa M, TRAN, Phuong Oanh T, POITOUT, Vincent

    Published in Diabetes (New York, N.Y.) (01-03-2002)
    “…Differential Effects of Hyperlipidemia on Insulin Secretion in Islets of Langerhans From Hyperglycemic Versus Normoglycemic Rats Isabelle Briaud 1 , Cynthia L…”
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  3. 3
    Inhibition of Insulin Secretion by Leptin in Normal Rodent Islets of Langerhans

    Inhibition of Insulin Secretion by Leptin in Normal Rodent Islets of Langerhans by Poitout, Vincent, Rouault, Christine, Guerre-Millo, Michèle, Briaud, Isabelle, Reach, Gérard

    Published in Endocrinology (Philadelphia) (01-03-1998)
    “…The recently discovered adipose cell-specific hormone called leptin decreases food intake and increases energy expenditure in rodents through a pathway…”
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  4. 4
    Differential Activation Mechanisms of Erk-1/2 and p70S6K by Glucose in Pancreatic β-Cells

    Differential Activation Mechanisms of Erk-1/2 and p70S6K by Glucose in Pancreatic β-Cells by BRIAUD, Isabelle, LINGOHR, Melissa K, DICKSON, Lorna M, WREDE, Christian E, RHODES, Christopher J

    Published in Diabetes (New York, N.Y.) (01-04-2003)
    “…Differential Activation Mechanisms of Erk-1/2 and p70 S6K by Glucose in Pancreatic β-Cells Isabelle Briaud , Melissa K. Lingohr , Lorna M. Dickson , Christian…”
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  5. 5
    Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via Ca2+-dependent calcineurin/NFAT signaling in primary pancreatic islet β-cells

    Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via Ca2+-dependent calcineurin/NFAT signaling in primary pancreatic islet β-cells by Demozay, Damien, Tsunekawa, Shin, Briaud, Isabelle, Shah, Ramila, Rhodes, Christopher J

    Published in Diabetes (New York, N.Y.) (01-11-2011)
    “…Insulin receptor substrate-2 (IRS-2) plays an essential role in pancreatic islet β-cells by promoting growth and survival. IRS-2 turnover is rapid in primary…”
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  6. 6
    FoxO feedback control of basal IRS-2 expression in pancreatic β-cells is distinct from that in hepatocytes

    FoxO feedback control of basal IRS-2 expression in pancreatic β-cells is distinct from that in hepatocytes by Tsunekawa, Shin, Demozay, Damien, Briaud, Isabelle, McCuaig, Jill, Accili, Domenico, Stein, Roland, Rhodes, Christopher J

    Published in Diabetes (New York, N.Y.) (01-11-2011)
    “…Appropriate regulation of insulin receptor substrate 2 (IRS-2) expression in pancreatic β-cells is essential to adequately compensate for insulin resistance…”
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  7. 7
    Protein Kinase B/Akt Prevents Fatty Acid-induced Apoptosis in Pancreatic β-Cells (INS-1)

    Protein Kinase B/Akt Prevents Fatty Acid-induced Apoptosis in Pancreatic β-Cells (INS-1) by Wrede, Christian E., Dickson, Lorna M., Lingohr, Melissa K., Briaud, Isabelle, Rhodes, Christopher J.

    Published in The Journal of biological chemistry (20-12-2002)
    “…Free fatty acids (FFA) have been reported to reduce pancreatic β-cell mitogenesis and to increase apoptosis. Here we show that the FFA, oleic acid, increased…”
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  8. 8
    Insulin Receptor Substrate-2 Proteasomal Degradation Mediated by a Mammalian Target of Rapamycin (mTOR)-induced Negative Feedback Down-regulates Protein Kinase B-mediated Signaling Pathway in β-Cells

    Insulin Receptor Substrate-2 Proteasomal Degradation Mediated by a Mammalian Target of Rapamycin (mTOR)-induced Negative Feedback Down-regulates Protein Kinase B-mediated Signaling Pathway in β-Cells by Briaud, Isabelle, Dickson, Lorna M., Lingohr, Melissa K., McCuaig, Jill F., Lawrence, John C., Rhodes, Christopher J.

    Published in The Journal of biological chemistry (21-01-2005)
    “…Regulation of insulin receptor substrate (IRS)-2 expression is critical to β-cell survival, but the mechanisms that control this are complex and undefined…”
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  9. 9
    Specific Regulation of IRS-2 Expression by Glucose in Rat Primary Pancreatic Islet β-Cells

    Specific Regulation of IRS-2 Expression by Glucose in Rat Primary Pancreatic Islet β-Cells by Lingohr, Melissa K., Briaud, Isabelle, Dickson, Lorna M., McCuaig, Jill F., Alárcon, Cristina, Wicksteed, Barton L., Rhodes, Christopher J.

    Published in The Journal of biological chemistry (09-06-2006)
    “…Insulin receptor substrate 2 (IRS-2) plays a critical role in pancreatic β-cells. Increased IRS-2 expression promotes β-cell growth and survival, whereas…”
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  10. 10
    FoxO feedback control of basal IRS-2 expression in pancreatic [beta]-cells is distinct from that in hepatocytes.(ORIGINAL ARTICLE)

    FoxO feedback control of basal IRS-2 expression in pancreatic [beta]-cells is distinct from that in hepatocytes.(ORIGINAL ARTICLE) by Tsunekawa, Shin, Demozay, Damien, Briaud, Isabelle, McCuaig, Jill, Accili, Domenico, Stein, Roland, Rhodes, Christopher J

    Published in Diabetes (New York, N.Y.) (01-11-2011)
    “…OBJECTIVE--Appropriate regulation of insulin receptor substrate 2 (IRS-2) expression in pancreatic [beta]-cells is essential to adequately compensate for…”
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  11. 11
    Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via [Ca.sup.2+]-dependent calcineurin/NFAT signaling in primary pancreatic islet β-cells

    Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via [Ca.sup.2+]-dependent calcineurin/NFAT signaling in primary pancreatic islet β-cells by Demozay, Damien, Tsunekawa, Shin, Briaud, Isabelle, Shah, Ramila, Rhodes, Christopher J

    Published in Diabetes (New York, N.Y.) (01-11-2011)
    “…OBJECTIVE--Insulin receptor substrate-2 (IRS-2) plays an essential role in pancreatic islet β-cells by promoting growth and survival. IRS-2 turnover is rapid…”
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  12. 12
    Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via [Ca.sup.2+]-dependent calcineurin/NFAT signaling in primary pancreatic islet [beta]-cells.(ORIGINAL ARTICLE)

    Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via [Ca.sup.2+]-dependent calcineurin/NFAT signaling in primary pancreatic islet [beta]-cells.(ORIGINAL ARTICLE) by Demozay, Damien, Tsunekawa, Shin, Briaud, Isabelle, Shah, Ramila, Rhodes, Christopher J

    Published in Diabetes (New York, N.Y.) (01-11-2011)
    “…OBJECTIVE--Insulin receptor substrate-2 (IRS-2) plays an essential role in pancreatic islet [beta]-cells by promoting growth and survival. IRS-2 turnover is…”
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  13. 13
    Specific Glucose-Induced Control of Insulin Receptor Substrate-2 Expression Is Mediated via Ca^sup 2+^-Dependent Calcineurin/NFAT Signaling in Primary Pancreatic Islet [Beta]-Cells

    Specific Glucose-Induced Control of Insulin Receptor Substrate-2 Expression Is Mediated via Ca^sup 2+^-Dependent Calcineurin/NFAT Signaling in Primary Pancreatic Islet [Beta]-Cells by Demozay, Damíen, Tsunekawa, Shin, Briaud, Isabelle, Shah, Ramila, Rhodes, Christopher J

    Published in Diabetes (New York, N.Y.) (01-11-2011)
    “…Insulin receptor substrate-2 (IRS-2) plays an essential role in pancreatic islet [beta]-cells by promoting growth and survival. IRS-2 turnover is rapid in…”
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  14. 14
    Differential activation mechanisms of Erk-1/2 and p70(S6K) by glucose in pancreatic beta-cells

    Differential activation mechanisms of Erk-1/2 and p70(S6K) by glucose in pancreatic beta-cells by Briaud, Isabelle, Lingohr, Melissa K, Dickson, Lorna M, Wrede, Christian E, Rhodes, Christopher J

    Published in Diabetes (New York, N.Y.) (01-04-2003)
    “…Glucose can activate the mitogen-activated kinases, Erk-1/2, and the ribosomal-S6 kinase, p70(S6K), in beta-cells, contributing to an increase in mitogenesis…”
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  15. 15
    Glucose-induced Translational Control of Proinsulin Biosynthesis Is Proportional to Preproinsulin mRNA Levels in Islet β-Cells but Not Regulated via a Positive Feedback of Secreted Insulin

    Glucose-induced Translational Control of Proinsulin Biosynthesis Is Proportional to Preproinsulin mRNA Levels in Islet β-Cells but Not Regulated via a Positive Feedback of Secreted Insulin by Wicksteed, Barton, Alarcon, Cristina, Briaud, Isabelle, Lingohr, Melissa K., Rhodes, Christopher J.

    Published in The Journal of biological chemistry (24-10-2003)
    “…Proinsulin biosynthesis is regulated in response to nutrients, most notably glucose. In the short term (≤2h) this is due to increases in the translation of…”
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  16. 16
    Specific Glucose-Induced Control of Insulin Receptor Substrate-2 Expression Is Mediated via Ca2+-Dependent Calcineurin/NFAT Signaling in Primary Pancreatic Islet β-cells

    Specific Glucose-Induced Control of Insulin Receptor Substrate-2 Expression Is Mediated via Ca2+-Dependent Calcineurin/NFAT Signaling in Primary Pancreatic Islet β-cells by DEMOZAY, Damien, TSUNEKAWA, Shin, BRIAUD, Isabelle, SHAH, Ramila, RHODES, Christopher J

    Published in Diabetes (New York, N.Y.) (2011)
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  17. 17
    FoxO Feedback Control of Basal IRS-2 Expression in Pancreatic β-Cells Is Distinct From That in Hepatocytes

    FoxO Feedback Control of Basal IRS-2 Expression in Pancreatic β-Cells Is Distinct From That in Hepatocytes by TSUNEKAWA, Shin, DEMOZAY, Damien, BRIAUD, Isabelle, MCCUAIG, Jill, ACCILI, Domenico, STEIN, Roland, RHODES, Christopher J

    Published in Diabetes (New York, N.Y.) (2011)
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  18. 18
    Anti-Tumor Activity of Novel Small Molecule Wnt Signaling Inhibitor, CWP232291, In Multiple Myeloma

    Anti-Tumor Activity of Novel Small Molecule Wnt Signaling Inhibitor, CWP232291, In Multiple Myeloma by Cha, Joo Young, Jung, Ji-Eun, Lee, Kwan-Hoo, Briaud, Isabelle, Tenzin, Fnu, Jung, Hee Kyung, Pyon, Younghee, Lee, Donghee, Chung, Jae Uk, Lee, Jong Heun, Oh, Se-Woong, Jung, Kyung Yun, Pai, Jin Keon, Emami, Kathy

    Published in Blood (19-11-2010)
    “…Abstract 3038 Multiple myeloma (MM), one of the most incurable hematological malignancies in adults, is a disorder of plasma cells characterized by…”
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  19. 19
    Abstract LB-176: Discovery of CWP232291: A novel and potent small molecule inhibitor of Wnt signaling in hematological malignacies

    Abstract LB-176: Discovery of CWP232291: A novel and potent small molecule inhibitor of Wnt signaling in hematological malignacies by Cha, Joo Young, Jung, Ji-Eun, Emami, Kathy, Briaud, Isabelle, Tenzin, Fnu, Pyon, Younghee, Lee, Donghee, Chung, Jae Uk, Lee, Jong Heun, Oh, Se-Woong, Jung, Kyung Yun, Pai, Jin Keon

    Published in Cancer research (Chicago, Ill.) (15-04-2010)
    “…Discussion Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 101st Annual Meeting of the American Association for Cancer…”
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  20. 20
    Ca2+-dependent dephosphorylation of kinesin heavy chain on beta-granules in pancreatic beta-cells. Implications for regulated beta-granule transport and insulin exocytosis

    Ca2+-dependent dephosphorylation of kinesin heavy chain on beta-granules in pancreatic beta-cells. Implications for regulated beta-granule transport and insulin exocytosis by Donelan, Matthew J., Morfini, Gerardo, Julyan, Richard, Sommers, Scott, Hays, Lori, Kajio, Hiroshi, Briaud, Isabelle, Easom, Richard A., Molkentin, Jeffery D., Brady, Scott T., Rhodes, Christopher J.

    Published in The Journal of biological chemistry (05-07-2002)
    “…The specific biochemical steps required for glucose-regulated insulin exocytosis from beta-cells are not well defined. Elevation of glucose leads to increases…”
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