Search Results - "Isabel Scherping"

Mitochondrial dysfunction: the first domino in brain aging and Alzheimer's disease? by Leuner, Kristina, Hauptmann, Susanne, Abdel-Kader, Reham, Scherping, Isabel, Keil, Uta, Strosznajder, Johanna B, Eckert, Anne, Müller, Walter E

“…With the increasing average life span of humans and with decreasing cognitive function in elderly individuals, age-related cognitive disorders including…”
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Proteomic and Functional Analyses Reveal a Mitochondrial Dysfunction in P301L Tau Transgenic Mice by David, Della C., Hauptmann, Susanne, Scherping, Isabel, Schuessel, Katrin, Keil, Uta, Rizzu, Patrizia, Ravid, Rivka, Dröse, Stefan, Brandt, Ulrich, Müller, Walter E., Eckert, Anne, Götz, Jürgen

“…Transgenic mice overexpressing the P301L mutant human tau protein exhibit an accumulation of hyperphosphorylated tau and develop neurofibrillary tangles. The…”
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Soluble beta-amyloid leads to mitochondrial defects in amyloid precursor protein and tau transgenic mice by Eckert, Anne, Hauptmann, Susanne, Scherping, Isabel, Rhein, Virginie, Müller-Spahn, Franz, Götz, Jürgen, Müller, Walter E

“…Mitochondrial dysfunction has been identified in neurodegenerative disorders including Alzheimer's disease, where accumulation of beta-amyloid (Abeta) and…”
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Mitochondrial dysfunction in sporadic and genetic Alzheimer's disease by Hauptmann, Susanne, Keil, Uta, Scherping, Isabel, Bonert, Astrid, Eckert, Anne, Müller, Walter E.

“…Increasing evidence suggests an important role of mitochondrial dysfunction in the pathogenesis of many common age-related neurodegenerative diseases,…”
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Piracetam improves mitochondrial dysfunction following oxidative stress by Keil, Uta, Scherping, Isabel, Hauptmann, Susanne, Schuessel, Katin, Eckert, Anne, Müller, Walter E

“…Mitochondrial dysfunction including decrease of mitochondrial membrane potential and reduced ATP production represents a common final pathway of many…”
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Stabilization of mitochondrial function by Ginkgo biloba extract (EGb 761) by Abdel-Kader, Reham, Hauptmann, Susanne, Keil, Uta, Scherping, Isabel, Leuner, Kristina, Eckert, Anne, Müller, Walter E.

“…A large body of data emphasizes the central role of mitochondrial dysfunction during aging and as an early event in neurodegenerative diseases. In this study…”
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Oligomeric and fibrillar species of β-amyloid (Aβ42) both impair mitochondrial function in P301L tau transgenic mice by Eckert, Anne, Hauptmann, Susanne, Scherping, Isabel, Meinhardt, Jessica, Rhein, Virginie, Dröse, Stefan, Brandt, Ulrich, Fändrich, Marcus, Müller, Walter E., Götz, Jürgen

“…We recently provided evidence for a mitochondrial dysfunction in P301L tau transgenic mice, a strain modeling the tau pathology of Alzheimer’s disease (AD) and…”
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Amyloid β-induced Changes in Nitric Oxide Production and Mitochondrial Activity Lead to Apoptosis by Keil, Uta, Bonert, Astrid, Marques, Celio A., Scherping, Isabel, Weyermann, Jörg, Strosznajder, Joanna B., Müller-Spahn, Franz, Haass, Christian, Czech, Christian, Pradier, Laurent, Müller, Walter E., Eckert, Anne

“…Increasing evidence suggests an important role of mitochondrial dysfunction in the pathogenesis of Alzheimer's disease. Thus, we investigated the effects of…”
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Stabilization of Mitochondrial Membrane Potential and Improvement of Neuronal Energy Metabolism by Ginkgo Biloba Extract EGb 761 by ECKERT, ANNE, KEIL, UTA, SCHERPING, ISABEL, HAUPTMANN, SUSANNE, MÜLLER, WALTER E.

“…Ginkgo biloba extract EGb 761 has been used for many years to treat age‐related cognitive disorders including Alzheimer's disease. EGb 761 given shortly after…”
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Oligomeric and fibrillar species of [beta]-amyloid (A[beta]42) both impair mitochondrial function in P301L tau transgenic mice by Eckert, Anne, Hauptmann, Susanne, Scherping, Isabel, Meinhardt, Jessica, Rhein, Virginie, Dröse, Stefan, Brandt, Ulrich, Fändrich, Marcus, Müller, Walter E, Götz, Jürgen

“…We recently provided evidence for a mitochondrial dysfunction in P301L tau transgenic mice, a strain modeling the tau pathology of Alzheimer's disease (AD) and…”
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Oligomeric and fibrillar species of β-amyloid (Aβ42) both impair mitochondrial function in P301L tau transgenic mice by ECKERT, Anne, HAUPTMANN, Susanne, SCHERPING, Isabel, MEINHARDT, Jessica, RHEIN, Virginie, DRÖSE, Stefan, BRANDT, Ulrich, FÄNDRICH, Marcus, MÜLLER, Walter E, GÖTZ, Jürgen

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Mitochondrial dysfunction induced by disease relevant AbetaPP and tau protein mutations by Keil, Uta, Hauptmann, Susanne, Bonert, Astrid, Scherping, Isabel, Eckert, Anne, Müller, Walter E

“…Alzheimer's disease is characterized by two major pathological hallmarks: extracellular plaques consisting of amyloid beta peptide and neurofibrillary tangles…”
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P4-001: Soluble amyloid-beta leads to mitochondrial failure in APP and tau transgenic mice by Eckert, Anne, Hauptmann, Susanne, Scherping, Isabel, Bonert, Astrid, Müller-Spahn, Franz, Götz, Jürgen, Müller, Walter E.

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P4-252 Impact of β-amyloid on mitochondrial failure in Alzheimer's disease by Eckert, Anne, Keil, Uta, Bonert, Astrid, Scherping, Isabel, Marques, Celio A., Haass, Christian, Czech, Christian, Pradier, Laurent, Müller, Walter E.

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Amyloid β-induced Changes in Nitric Oxide Production and Mitochondrial Activity Lead to Apoptosis by Uta Keil, Astrid Bonert, Celio A. Marques, Isabel Scherping, Jörg Weyermann, Joanna B. Strosznajder, Franz Müller-Spahn, Christian Haass, Christian Czech, Laurent Pradier, Walter E. Müller, Anne Eckert

“…Increasing evidence suggests an important role of mitochondrial dysfunction in the pathogenesis of Alzheimer's disease. Thus, we investigated the effects of…”
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