Search Results - "Isaacson, A"

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  1. 1

    A convergent reaction-diffusion master equation by Isaacson, Samuel A

    Published in The Journal of chemical physics (07-08-2013)
    “…The reaction-diffusion master equation (RDME) is a lattice stochastic reaction-diffusion model that has been used to study spatially distributed cellular…”
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  2. 2

    An unstructured mesh convergent reaction–diffusion master equation for reversible reactions by Isaacson, Samuel A., Zhang, Ying

    Published in Journal of computational physics (01-12-2018)
    “…The convergent reaction–diffusion master equation (CRDME) was recently developed to provide a lattice particle-based stochastic reaction–diffusion model that…”
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  3. 3

    THE REACTION-DIFFUSION MASTER EQUATION AS AN ASYMPTOTIC APPROXIMATION OF DIFFUSION TO A SMALL TARGET by ISAACSON, SAMUEL A.

    Published in SIAM journal on applied mathematics (01-01-2009)
    “…The reaction-diffusion master equation (RDME) has recently been used as a model for biological systems in which both noise in the chemical reaction process and…”
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  4. 4

    The promise of big data for precision population health management in the US by Han, A., Isaacson, A., Muennig, P.

    Published in Public health (London) (01-08-2020)
    “…As we enter the year 2020, health data in the United States (US) is still in the process of being curated into a usable format. With coordinated data systems,…”
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  5. 5

    Catalyst: Fast and flexible modeling of reaction networks by Loman, Torkel E, Ma, Yingbo, Ilin, Vasily, Gowda, Shashi, Korsbo, Niklas, Yewale, Nikhil, Rackauckas, Chris, Isaacson, Samuel A

    Published in PLoS computational biology (18-10-2023)
    “…We introduce Catalyst.jl, a flexible and feature-filled Julia library for modeling and high-performance simulation of chemical reaction networks (CRNs)…”
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  6. 6

    Strong intracellular signal inactivation produces sharper and more robust signaling from cell membrane to nucleus by Ma, Jingwei, Do, Myan, Le Gros, Mark A, Peskin, Charles S, Larabell, Carolyn A, Mori, Yoichiro, Isaacson, Samuel A

    Published in PLoS computational biology (16-11-2020)
    “…For a chemical signal to propagate across a cell, it must navigate a tortuous environment involving a variety of organelle barriers. In this work we study…”
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  7. 7

    The influence of volume exclusion by chromatin on the time required to find specific DNA binding sites by diffusion by Isaacson, S. A., McQueen, D. M., Peskin, Charles S.

    “…Within the nuclei of eukaryotic cells, the density of chromatin is nonuniform. We study the influence of this nonuniform density, which we derive from…”
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  8. 8

    Reaction-diffusion master equation, diffusion-limited reactions, and singular potentials by Isaacson, Samuel A, Isaacson, David

    “…To model biochemical systems in which both noise in the chemical reaction process and spatial movement of molecules is important, both the reaction-diffusion…”
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  9. 9

    How Retroactivity Affects the Behavior of Incoherent Feedforward Loops by Wang, Junmin, Belta, Calin, Isaacson, Samuel A.

    Published in iScience (18-12-2020)
    “…An incoherent feedforward loop (IFFL) is a network motif known for its ability to accelerate responses and generate pulses. It remains an open question to…”
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    A First-Passage Kinetic Monte Carlo method for reaction–drift–diffusion processes by Mauro, Ava J., Sigurdsson, Jon Karl, Shrake, Justin, Atzberger, Paul J., Isaacson, Samuel A.

    Published in Journal of computational physics (15-02-2014)
    “…Stochastic reaction–diffusion models are now a popular tool for studying physical systems in which both the explicit diffusion of molecules and noise in the…”
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