Search Results - "Isaacs, S T"

Photochemical inactivation of viruses and bacteria in platelet concentrates by use of a novel psoralen and long-wavelength ultraviolet light by Lin, L., Cook, D. N., Wiesehahn, G. P., Alfonso, R., Behrman, B., Cimino, G. D., Corten, L., Damonte, P. B., Dikeman, R., Dupuis, K., Fang, Y. M., Hanson, C. V., Hearst, J. E., Lin, C. Y., Londe, H. F., Metchette, K., Nerio, A. T., Pu, J. T., Reames, A. A., Rheinschmidt, M., Tessman, J., Isaacs, S. T., Wollowitz, S., Corash, L.

“…BACKGROUND: A photochemical treatment process has been developed for the inactivation of viruses and bacteria in platelet concentrates. This process is based…”
Get full text

Psoralens as Photoactive Probes of Nucleic Acid Structure and Function: Organic Chemistry, Photochemistry, and Biochemistry by Cimino, G D, Gamper, H B, Isaacs, S T, Hearst, J E

Get full text

Post-PCR sterilization : a method to control carryover contamination for the polymerase chain reaction by CIMINO, G. D, METCHETTE, K. C, TESSMAN, J. W, HEARST, J. E, ISAACS, S. T

“…We describe a photochemical procedure for the sterilization of polynucleotides that are created by the Polymerase Chain Reaction (PCR). The procedure is based…”
Get full text

Photochemistry of the furan-side 8-methoxypsoralen-thymidine monoadduct inside the DNA helix. Conversion to diadduct and to pyrone-side monoadduct by Tessman, John W, Isaacs, Stephen T, Hearst, John E

“…We have studied the photochemical reactions of 8-methoxypsoralen (8-MOP) with calf thymus DNA. Analysis of the photoproducts formed was carried out by…”
Get full text

Post-PCR sterilization : development and application to an HIV-1 diagnostic assay by ISAACS, S. T, TESSMAN, J. W, METCHETTE, K. C, HEARST, J. E, CIMINO, G. D

“…We have developed an effective post-PCR sterilization process and have applied the procedure to a diagnostic assay for HIV-1. The method, which is based on…”
Get full text

The reaction of the psoralens with deoxyribonucleic acid by Hearst, J E, Isaacs, S T, Kanne, D, Rapoport, H, Straub, K

Get more information

The use of exonuclease III for polymerase chain reaction sterilization by YU SHENG ZHU, ISAACS, S. T, CIMINO, G. D, HEARST, J. E

“…Images…”
Get full text

The molecular and stereochemical structures of photoproducts generated by UV-irradiation of 4'-hydroxymethyl-4,5',8'-trimethylpsoralen in aqueous solution by Kao, J P, Isaacs, S T, Hearst, J E

“…UV irradiation of 4'-hydroxymethyl-4,5',8-trimethyl psoralen (HMT) in aqueous solution yields three major photoproducts. We have isolated and characterized (1)…”
Get more information

Reverse Southern hybridization by Gamper, Howard B., Cimino, George D., Isaacs, Stephen T., Ferguson, Martin, Hearst, John E.

“…A DNA oligomer 25 nucleotides long which contained an HMT (4'-hydroxymethyl-4, 5', 8-trimethylpsoralen) furan side monoadduct to thymidine at a 5'-TpA-3' site…”
Get full text

More false-positive problems by CIMINO, GEORGE D, METCHETTE, KENNETH, ISAACS, STEPHEN T, ZHU, YU SHENG

“…[...]their conclusion that the oligonucleotide primers for the PCR retain their full functional integrity after irradiation is not warranted. [...]the critical…”
Get full text

Synthesis and characterization of new psoralen derivatives with superior photoreactivity with DNA and RNA by Isaacs, Stephen T, Shen, Che-Kun James, Hearst, John E, Rapoport, Henry

“…The synthesis of five new psoralen derivatives is described. Three of these, 4'-hydroxymethyl-4,5',8-trimethylpsoralen,…”
Get full text

Resistance of the scrapie agent to inactivation by psoralens by McKinley, M P, Masiarz, F R, Isaacs, S T, Hearst, J E, Prusiner, S B

Get more information

The site-specific inhibition of Bgl I cleavage by psoralen photoadducts by Ostrander, E A, Robinson, G W, Isaacs, S T, Tessman, J, Hallick, L M

Get more information

In vitro characterization of the reaction of four psoralen derivatives with DNA by Isaacs, S T, Wiesehahn, G, Hallick, L M

“…Four psoralen derivatives were radiolabeled and used for in vitro DNA binding studies. The derivatives were compared for their dark-binding ability to DNA,…”
Get more information

Patents and literature by Linhardt, Robert J., Albarella, J. P., Anderson, L. H. D., Paau, A., Platt, S. G., Sequeira, L., Ranki, T. M., Soderlund, H. E., Sheldon, E. L., Levenson, C. H., Mullis, K. B., Rapoport, H., Watson, R. M., Yabusaki, K. K., Isaacs, S. T., Gamper, Howard, B., Armenia, R. D., Gibbons, I., Baker, T. S., Abbott, S. R., Simpson, J. G., Wright, J. F., Powell, M. J., Baldeschwieler, J. D., Gamble, R. C., Lin, A. M., Tin, G. W., Baldwin, T. O., Holzman, T. F., Satoh, P. S., Yein, F. S., Block, M. J., Hirschfeld, T. B., Burton, J. A., Hoop, B., Chagnon, M. S., Grotnan, E. V., Josephson, L., Whitehead, R. A., Chandler, H. M., Healey, K., Hurrell, J. G. R., Chang, T. W., Deutsch, A., Dorsey, N., Diamond, S. E., Regina, F. J., Frey, W. A., Simons, D. M., Gadow, A. E., Wood, W. G., Hinshaw, J. C., Toner, J. L., Reynolds, G. A., Karmen, A., Lasky, F. D., Kerschensteiner, D., Kirkemo, C. L., Shipchandler, M. T., Kosak, K. M., Kricka, L. J., Thorpe, G. H. G. H., Whitehead, T. P., Kung, V. T., Canova, D. E., Lau-Hon-Peng, P., Yang, E. K., Jacobson, H. W., Nicoli, D. F., Elings, V. B., Parham, M., Warren, W. J., Rokugawa, K., Self, C. H., Tokinaga, D., Kobayashi, T., Imai, K., Tsay, Y. G., Shah, V. D., Wang, C. H. J., Stroupe, S. D., Jolley, M. E., Zuk, R. F., Litman, D. J., Fossati, P., Freeman, A., Tor, R., Gallacher, J. J., Higgins, I. J., Hill, H. A. O., Plotkin, E. V., Page, D. J., Walton, N. J., Whitford, D., Itoh, N., Matsunaga, K., Karasawa, Y., Takata, Y., Kusakabe, H.

Get full text

Photochemistry of the furan-side 8-methoxypsoralen-thymidine monoadduct inside the DNA helix. Conversion to diadduct andto pyrone-side monoadduct by Tessman, J W, Isaacs, ST, Hearst, JE

“…The authors have studied the photochemical reactions of 8-methoxysoralen (8-MOP) with calf thymus DNA. Analysis of the photoproducts formed was carried out by…”
Get full text

Adherence to the American Society for Colposcopy and Cervical Pathology guidelines: an observational study by Sarah Kay Conrad, Bassam Dahman, Anita Kumar, Jordan Hylton, Christine Isaacs

“…Objective The 2012 American Society for Colposcopy and Cervical Pathology (ASCCP) guidelines were developed to provide guidance regarding cervical pathology…”
Get full text

Clinicopathological Features of Upper Third Gastric Cancer during a 21-Year Period (Single Center Analysis) by Jang, Je-Ho, Beron, Reinaldo Isaacs, Ahn, Hye-Seong, Kong, Seong-Ho, Lee, Hyuk-Joon, Kim, Woo-Ho, Lee, Kuhn-Uk, Yang, Han-Kwang

“…Purpose: The aim of this study was to determine proportions of upper third gastric cancer (UTG) among all gastric cancers and analyze clinicopathological…”
Get full text