Search Results - "Isaac Yang"
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Postoperative Hearing Preservation in Patients Undergoing Retrosigmoid Craniotomy for Resection of Vestibular Schwannomas: A Systematic Review of 2034 Patients
Published in Neurosurgery (01-03-2020)“…Abstract BACKGROUND Vestibular schwannomas (VS) are benign tumors derived from Schwann cells ensheathing the vestibulocochlear nerve. The retrosigmoid (RS)…”
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Utilizing virtual and augmented reality for educational and clinical enhancements in neurosurgery
Published in Journal of clinical neuroscience (01-01-2017)“…Highlights • Virtual reality (VR) and augmented reality (AR) have great potential in neurosurgery. • Immersive VR has the potential to be used an educational…”
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Detection of wild-type EGFR amplification and EGFRvIII mutation in CSF-derived extracellular vesicles of glioblastoma patients
Published in Neuro-oncology (Charlottesville, Va.) (19-10-2017)“…RNAs within extracellular vesicles (EVs) have potential as diagnostic biomarkers for patients with cancer and are identified in a variety of biofluids…”
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Efficient sampling over rough energy landscapes with high barriers: A combination of metadynamics with integrated tempering sampling
Published in The Journal of chemical physics (07-03-2016)“…In order to efficiently overcome high free energy barriers embedded in a complex energy landscape and calculate overall thermodynamics properties using…”
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The role of CD44 in glioblastoma multiforme
Published in Journal of clinical neuroscience (01-12-2016)“…Highlights • Glioblastoma multiforme (GBM) is the most common and deadly primary brain tumor. • CD44 is a transmembrane molecule overexpressed in GBM. •…”
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Understanding the Role of Endothelial Cells in Glioblastoma: Mechanisms and Novel Treatments
Published in International journal of molecular sciences (01-06-2024)“…Glioblastoma is a highly aggressive neoplasm and the most common primary malignant brain tumor. Endothelial tissue plays a critical role in glioblastoma growth…”
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miRNA contents of cerebrospinal fluid extracellular vesicles in glioblastoma patients
Published in Journal of neuro-oncology (01-06-2015)“…Analysis of extracellular vesicles (EVs) derived from plasma or cerebrospinal fluid (CSF) has emerged as a promising biomarker platform for therapeutic…”
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The role of microglia in central nervous system immunity and glioma immunology
Published in Journal of clinical neuroscience (01-01-2010)“…Abstract The central nervous system (CNS) historically has been considered an immune-privileged organ, lacking a lymphatic system and shielded from the…”
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Dynamics and Kinetics Study of “In-Water” Chemical Reactions by Enhanced Sampling of Reactive Trajectories
Published in The journal of physical chemistry. B (12-11-2015)“…High potential energy barriers and engagement of solvent coordinates set challenges for in silico studies of chemical reactions, and one is quite commonly…”
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Radiotherapy versus combination radiotherapy-bevacizumab for the treatment of recurrent high-grade glioma: a systematic review
Published in Acta neurochirurgica (01-07-2021)“…Background High-grade gliomas (HGG) comprise the most common primary adult brain cancers and universally recur. Combination of re-irradiation therapy (reRT)…”
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Simultaneous radiosurgery for multiple brain metastases: technical overview of the UCLA experience
Published in Radiation oncology (London, England) (17-11-2021)“…To communicate our institutional experience with single isocenter radiosurgery treatments for multiple brain metastases, including challenges with determining…”
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A comprehensive analysis of hearing preservation after radiosurgery for vestibular schwannoma
Published in Journal of neurosurgery (01-04-2010)“…Gamma Knife surgery (GKS) has evolved into a practical alternative to open microsurgical resection in the treatment of patients with vestibular schwannoma…”
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Monitoring of regulatory T cell frequencies and expression of CTLA-4 on T cells, before and after DC vaccination, can predict survival in GBM patients
Published in PloS one (02-04-2012)“…Dendritic cell (DC) vaccines have recently emerged as an innovative therapeutic option for glioblastoma patients. To identify novel surrogates of anti-tumor…”
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Increased cochlear radiation dose predicts delayed hearing loss following both stereotactic radiosurgery and fractionated stereotactic radiotherapy for vestibular schwannoma
Published in Journal of neuro-oncology (01-11-2019)“…Purpose Stereotactic radiosurgery (SRS) and fractionated stereotactic radiotherapy (fSRT) are noninvasive therapies for vestibular schwannomas providing…”
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Laser neurosurgery: A systematic analysis of magnetic resonance-guided laser interstitial thermal therapies
Published in Journal of clinical neuroscience (01-02-2017)“…Highlights • Differences between systems are probe design, delivery, cooling, and wavelength. • Epilepsy is the most common indication for Visualase therapy. •…”
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Optimizing preservation of extracellular vesicular miRNAs derived from clinical cerebrospinal fluid
Published in Cancer biomarkers : section A of Disease markers (25-03-2016)“…Tumor specific genetic material can be detected in extracellular vesicles (EVs) isolated from blood, cerebrospinal fluid (CSF), and other biofluids of…”
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Transferrin receptors and glioblastoma multiforme: Current findings and potential for treatment
Published in Journal of clinical neuroscience (01-07-2015)“…Abstract The current standard treatment for glioblastoma multiforme (GBM) is surgery followed by chemotherapy and external radiation. Even with the standard…”
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The molecular genetics and tumor pathogenesis of meningiomas and the future directions of meningioma treatments
Published in Neurosurgical focus (01-05-2011)“…Meningiomas are mostly benign, slow-growing tumors of the CNS that originate from arachnoidal cap cells. While monosomy 22 is the most frequent genetic…”
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Ossified spinal epidermoid cyst: A systematic review and case report
Published in Heliyon (30-09-2024)“…Epidermoid cysts (ECs) are rare, benign lesions which comprise less than 1 % of all spinal tumors. Calcification of spinal ECs is rare, and EC ossification…”
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Endocrinologic, neurologic, and visual morbidity after treatment for craniopharyngioma
Published in Journal of neuro-oncology (01-02-2011)“…Craniopharyngiomas are locally aggressive tumors which typically are focused in the sellar and suprasellar region near a number of critical neural and vascular…”
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