Search Results - "Irwin, J. C."

Mesenchymal Stem/Progenitors and Other Endometrial Cell Types From Women With Polycystic Ovary Syndrome (PCOS) Display Inflammatory and Oncogenic Potential by Piltonen, T. T, Chen, J, Erikson, D. W, Spitzer, T. L. B, Barragan, F, Rabban, J. T, Huddleston, H, Irwin, J. C, Giudice, L. C

“…Context: Endometrium in polycystic ovary syndrome (PCOS) presents altered gene expression indicating progesterone resistance and predisposing to reduced…”
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Nuclear receptor, coregulator signaling, and chromatin remodeling pathways suggest involvement of the epigenome in the steroid hormone response of endometrium and abnormalities in endometriosis by Zelenko, Z, Aghajanova, L, Irwin, J C, Giudice, Linda C

“…Human endometrium, a steroid hormone-dependent tissue, displays complex cellular regulation mediated by nuclear receptors (NRs). The NRs interact with…”
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Ectopic uterine tissue as a chronic pain generator by Alvarez, P, Chen, X, Hendrich, J, Irwin, J.C, Green, P.G, Giudice, L.C, Levine, J.D

“…Highlights ► Uterine tissue implanted in gastrocnemius muscle produced endometriosis-like lesions. ► Lesions exhibited mechanical hyperalgesia and increased…”
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The human oviduct transcriptome reveals an anti-inflammatory, anti-angiogenic, secretory and matrix-stable environment during embryo transit by Hess, A.P, Talbi, S, Hamilton, A.E, Baston-Buest, D.M, Nyegaard, M, Irwin, J.C, Barragan, F, Kruessel, J.S, Germeyer, A, Giudice, L.C

“…Abstract The human oviduct serves as a conduit for spermatozoa in the peri-ovulatory phase and nurtures and facilitates transport of the developing embryo for…”
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Endometrial stromal fibroblasts from women with polycystic ovary syndrome have impaired progesterone-mediated decidualization, aberrant cytokine profiles and promote enhanced immune cell migration in vitro by Piltonen, T.T., Chen, J.C., Khatun, M., Kangasniemi, M., Liakka, A., Spitzer, T., Tran, N., Huddleston, H., Irwin, J.C., Giudice, L.C.

“…STUDY QUESTION Do endometrial stromal fibroblasts (eSF) in women with polycystic ovary syndrome (PCOS) (eSFpcos) exhibit altered estrogen and/or progesterone…”
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Identification and regulation of the IGFBP-4 protease and its physiological inhibitor in human trophoblasts and endometrial stroma: Evidence for paracrine regulation of IGF-II bioavailability in the placental bed during human implantation by GIUDICE, L. C, CONOVER, C. A, OVERGAARD, M. T, OXVIG, C, BALE, L, FAESSEN, G. H, ILG, K, SUN, I, IMANI, B, SUEN, L.-F, IRWIN, J. C, CHRISTIANSEN, M

“…The IGF family plays an important role in implantation and placental physiology. IGF-II is abundantly expressed by placental trophoblasts, and IGF binding…”
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Insulin-like growth factor (IGF)-II inhibition of endometrial stromal cell tissue inhibitor of metalloproteinase-3 and IGF-binding protein-1 suggests paracrine interactions at the decidua :trophoblast interface during human implantation by IRWIN, Juan C, SUEN, Lii-Fang, FAESSEN, Gerry H, POPOVICI, Roxana M, GIUDICE, Linda C

“…In human pregnancy, insulin-like growth factor (IGF)-II messenger RNA (mRNA) is expressed at the maternal-fetal interface exclusively by the placental…”
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Crystalline structure, electronic and lattice-dynamics properties of NbTe2 by Barajas-Aguilar, Aarón Hernán, Irwin, J. C., Garay-Tapia, Andrés Manuel, Schwarz, Torsten, Paraguay Delgado, Francisco, Brodersen, P. M., Prinja, Rajiv, Kherani, Nazir, Jiménez Sandoval, Sergio J.

“…Layered-structure materials are currently relevant given their quasi-2D nature. Knowledge of their physical properties is currently of major interest. Niobium…”
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Role of the IGF system in trophoblast invasion and pre-eclampsia by Irwin, J.C., Suen, L.-F., Martina, N.A., Mark, S.P., Giudice, L.C.

“…Insulin-like growth factor-II (IGF-II) and IGF binding protein-1 (IGFBP-1) appear to play an important role in paracrine interactions at the maternal–fetal…”
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Hypoxia and cAMP Stimulate Vascular Endothelial Growth Factor (VEGF) in Human Endometrial Stromal Cells: Potential Relevance to Menstruation and Endometrial Regeneration by Popovici, R. M, Irwin, J. C, Giaccia, A. J, Giudice, L. C

“…The human female reproductive tract shows unique cycle-specific changes in vascularization. Vascular endothelial growth factor (VEGF) is a specific vascular…”
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Cumulative effects from repeated exposures to suberythemal doses of UVB and UVA in human skin by Lavker, Robert M, Gerberick, G.Frank, Veres, Denise, Irwin, Chris J, Kaidbey, Kays H

“…Background : The skin is repeatedly exposed to solar UV radiation. Long-term photodamage is a consequence of cumulative UV radiation injury. Hence an…”
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Hypoxia and cAMP stimulate vascular endothelial growth factor (VEGF) in human endometrial stromal cells : Potential relevance to menstruation and endometrial regeneration by POPOVICI, R. M, IRWIN, J. C, GIACCIA, A. J, GIUDICE, L. C

“…The human female reproductive tract shows unique cycle-specific changes in vascularization. Vascular endothelial growth factor (VEGF) is a specific vascular…”
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Paracrine actions of insulin-like growth factors and IGF binding protein-1 in non-pregnant human endometrium and at the decidual–trophoblast interface by Giudice, L.C, Mark, S.P, Irwin, J.C

“…Insulin-like growth factors, IGF-I, IGF-II, and IGF binding protein (IGFBP-1) appear to play major roles in endometrial development during the menstrual cycle…”
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Quantitative assessment of cumulative damage from repetitive exposures to suberythemogenic doses of UVA in human skin by Lavker, R M, Veres, D A, Irwin, C J, Kaidbey, K H

“…Daily exposures to relatively small suberythemogenic fluences of UVA (50-200 kJ/m2) for 8 days resulted in cumulative morphological skin alterations indicative…”
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Evidence for two superconducting gaps in MgB2 by Chen, X K, Konstantinovic, M J, Irwin, J C, Lawrie, D D, Franck, J P

“…We have measured the Raman spectra of polycrystalline MgB2 from 25 to 1200 cm(-1). A superconductivity-induced redistribution in the electronic Raman continuum…”
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Cytokine-mediated regulation of 92-kilodalton type IV collagenase, tissue inhibitor of metalloproteinase-1 (TIMP-1), and TIMP-3 messenger ribonucleic acid expression in human endometrial stromal cells by HUANG, H.-Y, YAN WEN, IRWIN, J. C, KRUESSEL, J. S, SOONG, Y.-K, POLAN, M. L

“…Interleukin-1 (IL-1) is expressed in human endometrium and has been shown to play an integral role in local cellular interactions during implantation. In…”
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Human endometrial matrix metalloproteinase-2, a putative menstrual proteinase. Hormonal regulation in cultured stromal cells and messenger RNA expression during the menstrual cycle by Irwin, J C, Kirk, D, Gwatkin, R B, Navre, M, Cannon, P, Giudice, L C

“…Proteinases are likely effectors of endometrial menstrual breakdown. We have investigated proteinase production by human endometrial stromal cells subjected in…”
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Hormonal regulation of human endometrial stromal cells in culture: an in vitro model for decidualization by Irwin, J C, Kirk, D, King, R J, Quigley, M M, Gwatkin, R B

“…Stromal cells derived from proliferative or secretory human endometria, cultured in the absence of steroid hormones, grew as monolayers that showed only…”
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The insulin-like growth factor system in human peritoneal fluid: its effects on endometrial stromal cells and its potential relevance to endometriosis by Giudice, L C, Dsupin, B A, Gargosky, S E, Rosenfeld, R G, Irwin, J C

“…Peritoneal fluid (PF) lines the abdomen and pelvis and is believed to contain growth factors that stimulate endometriosis, a benign gynecological condition…”
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Sex steroids and growth factors differentially regulate the growth and differentiation of cultured human endometrial stromal cells by Irwin, J C, Utian, W H, Eckert, R L

“…We have studied the interaction between growth factors and sex steroids in regulating human endometrial stromal cell growth and differentiation using an in…”
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