Search Results - "Irwin, Christopher R"

Human Dental Pulp Fibroblasts Express the “Cold-sensing” Transient Receptor Potential Channels TRPA1 and TRPM8 by El Karim, Ikhlas A., BDS, PhD, Linden, Gerard J., BSc, BDS, PhD, Curtis, Timothy M., BSc, PhD, About, Imad, MS, PhD, McGahon, Mary K., BSc, PhD, Irwin, Christopher R., BSc, BDS, PhD, Killough, Simon A., BSc, BDS, PhD, Lundy, Fionnuala T., BSc, PhD

“…Abstract Introduction Transient receptor potential (TRP) channels comprise a group of nonselective calcium-permeable cationic channels, which are polymodal…”
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Natural Antimicrobials in the Dental Pulp by Lundy, Fionnuala T., Irwin, Christopher R., McLean, Denise F., Linden, Gerard J., El Karim, Ikhlas A.

“…Like many tissues, the dental pulp is equipped with innate and adaptive immune responses, designed to defend against infection and limit its spread. The pulp’s…”
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Differential regulation of NPY and SP receptor expression in STRO‐1+ve PDLSCs by inflammatory cytokines by Winning, Lewis, El Karim, Ikhlas A., Linden, Gerard J., Irwin, Christopher R., Killough, Simon A., Lundy, Fionnuala T.

“…Objectives The aims of this study were to investigate neuropeptide receptor expression regulation on STRO‐1 +ve periodontal ligament stem cells (PDLSCs) in…”
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Invasive front grading: reliability and usefulness in the management of oral squamous cell carcinoma by Sawair, Faleh A., Irwin, Christopher R., Gordon, Derek J., Leonard, Alan G., Stephenson, Mike, Napier, Séamus S.

“…Background:  The value of histological grading was examined with emphasis on reliability of assessment in 102 cases of intraoral squamous cell carcinoma from…”
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Sialylation of Porphyromonas gingivalis LPS and its effect on bacterial-host interactions by Zaric, Svetislav S, Lappin, Mark J, Fulton, Catherine R, Lundy, Fionnuala T, Coulter, Wilson A, Irwin, Christopher R

“…Porphyromonas gingivalis produces different LPS isoforms with significant structural variations of their lipid A and O-antigen moieties that can affect its…”
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Antimicrobial and immunomodulatory properties of PGLa-AM1, CPF-AM1, and magainin-AM1: Potent activity against oral pathogens by McLean, Denise T.F., McCrudden, Maelíosa T.C., Linden, Gerard J., Irwin, Christopher R., Conlon, J. Michael, Lundy, Fionnuala T.

“…Cationic amphipathic α-helical peptides are intensively studied classes of host defence peptides (HDPs). Three peptides, peptide glycine–leucine–amide…”
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Altered Toll-like Receptor 2-mediated Endotoxin Tolerance Is Related to Diminished Interferon β Production by Zaric, Svetislav S., Coulter, Wilson A., Shelburne, Charles E., Fulton, Catherine R., Zaric, Marija S., Scott, Aaron, Lappin, Mark J., Fitzgerald, Denise C., Irwin, Christopher R., Taggart, Clifford C.

“…Induction of endotoxin tolerance leads to a reduced inflammatory response after repeated challenge by LPS and is important for resolution of inflammation and…”
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Design, characterisation and preliminary clinical evaluation of a novel mucoadhesive topical formulation containing tetracycline for the treatment of periodontal disease by Jones, David S, Woolfson, A.David, Brown, Andrew F, Coulter, Wilson A, McClelland, Cathy, Irwin, Christopher R

“…This study describes the formulation, characterisation and preliminary clinical evaluation of mucoadhesive, semi-solid formulations containing…”
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Physicochemical characterization and preliminary in vivo efficacy of bioadhesive, semisolid formulations containing flurbiprofen for the treatment of gingivitis by Jones, D S, Irwin, C R, Woolfson, A D, Djokic, J, Adams, V

“…In this study, the physicochemical properties and preliminary in vivo clinical performance of formulations containing hydroxyethylcellulose (HEC; 3, 5, 10%…”
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Inter- and intra-site heterogeneity in the expression of fetal-like phenotypic characteristics by gingival fibroblasts : potential significance for wound healing by IRWIN, C. R, PICARDO, M, ELLIS, I, SLOAN, P, GREY, A. M, MCGURK, M, SCHOR, S. L

“…We have previously reported that fetal and adult skin fibroblasts display distinctive migratory phenotypes on 3-D collagen substrata and that these behavioural…”
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The effects of culture environment on the response of human gingival fibroblasts to cyclosporin A by James, J A, Irwin, C R, Linden, G J

“…In contrast to monolayer cell culture, the use of a 3-dimensional culture system creates an environment which is more physiologically comparable to conditions…”
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The Influence of Transforming Growth Factor‐β1 Gene Polymorphisms on the Severity of Gingival Overgrowth Associated With Concomitant Use of Cyclosporin A and a Calcium Channel Blocker by Linden, Gerard J., Haworth, Simone E., Maxwell, A. Peter, Poulton, Kay V., Dyer, Philip A, Middleton, Derek, Irwin, Christopher R., Marley, John J., McNamee, Peter, Short, Colin D., Hull, Peter S., James, Jacqueline A.

“…Background: The purpose of this study was to determine whether the prevalence and severity of gingival overgrowth in renal transplant recipients concomitantly…”
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