Search Results - "Irving, Nicholas"

A mouse model for Down syndrome exhibits learning and behaviour deficits by Reeves, Roger H, Irving, Nicholas G, Moran, Timothy H, Wohn, Anny, Kitt, Cheryl, Sisodia, Sangram S, Schmidt, Cecilia, Bronson, Roderick T, Davisson, Muriel T

“…Trisomy 21 or Down syndrome (DS) is the most frequent genetic cause of mental retardation, affecting one in 800 live born human beings. Mice with segmental…”
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Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease by McLoughlin, Declan M., Irving, Nicholas G., Brownlees, Janet, Brion, Jean-Pierre, Leroy, Karelle, Miller, Christopher C. J.

“…Aberrant metabolism of the amyloid precursor protein (APP) is believed to be at least part of the pathogenic process in Alzheimer's disease. The…”
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Development of a novel high-throughput assay for the investigation of GlyT-1b neurotransmitter transporter function by Allan, Lynda, Leith, J Lianne, Papakosta, Marianthi, Morrow, John A, Irving, Nicholas G, McFerran, Brian W, Clark, Alan G

“…The glycine transporter (GlyT-1b) is a Na(+)/Cl(-)-dependent electrogenic transporter which mediates the rapid re-uptake of glycine from the synaptic cleft…”
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Tau phosphorylation in transgenic mice expressing glycogen synthase kinase-3β transgenes by Brownlees, Janet, Irving, Nicholas G, Brion, Jean-Pierre, M. Gibb, Barry J, Wagner, Uta, Woodgett, James, J. Miller, Christopher C

“…IN order to investigate the effect on tau of manipulating glycogen synthase kinase (GSK)-3β activity in the brain, we created transgenic mice harbouring…”
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Fe65 and XIIβ co-localize with and compete for binding to the amyloid precursor protein by LAU, Kwok-Fai, MCLOUGHLIN, Declan M, STANDEN, Claire L, IRVING, Nicholas G, MILLER, Christopher C. J

“…The Fe65s and XIIs are two families of adaptor proteins that bind to the Alzheimer's disease amyloid precursor protein (APP). Although both the XIIs and Fe65s…”
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Overexpression of the mouse dishevelled-1 protein inhibits GSK-3β-mediated phosphorylation of tau in transfected mammalian cells by Wagner, Uta, Brownlees, Janet, Irving, Nicholas G, Lucas, Fiona R, Salinas, Patricia C, Miller, Christopher C.J

“…Tau is a neuronal microtubule-associated protein whose function is modulated by phosphorylation. GSK-3β is a tau kinase. GSK-3β is part of the wingless…”
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Tau phosphorylation in cells transfected with wild-type or an Alzheimer's disease mutant Presenilin 1 by Irving, Nicholas G, Miller, Christopher C.J

“…We have studied the effect of overexpressing either wild-type or an Alzheimer's disease mutant Presenilin 1 (PS1) on tau phosphorylation in transfected Chinese…”
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Fe65 and X11β co-localize with and compete for binding to the amyloid precursor protein by Lau, Kwok-Fai, McLoughlin, Declan M, Standen, Claire L, Irving, Nicholas G, Miller, Christopher C. J

“…The Fe65s and XIIs are two families of adaptor proteins that bind to the Alzheimerʼs disease amyloid precursor protein (APP). Although both the XIIs and Fe65s…”
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Mapping of the human and murine X11-like genes (APBA2 and apba2), the murine Fe65 gene (Apbb1), and the human Fe65-like gene (APBB2): genes encoding phosphotyrosine-binding domain proteins that interact with the Alzheimer's disease amyloid precursor protein by Blanco, G, Irving, N G, Brown, S D, Miller, C C, McLoughlin, D M

“…In order to map the human APBA2 and APBB2 genes, we selected PCR primers from the previously identified cDNA clones and overlapping sequences deposited in the…”
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A "tea bag" drying technique by Irving, Nicholas M

“…A quicker method for drying organic liquids…”
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Inorganic waste disposal by Irving, Nicholas M

“…The author shares a practical way to trap hazardous inorganic lab waste and make its disposal safe…”
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The discovery of novel 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamides as vasopressin V 1A receptor antagonists by Napier, Susan, Wishart, Grant, Arbuckle, William, Baker, James, Barn, David, Bingham, Matilda, Brown, Angus, Byford, Alan, Claxton, Chris, Craighead, Mark, Buchanan, Kirsteen, Fielding, Lee, Gibson, Lindsay, Goodwin, Richard, Goutcher, Susan, Irving, Nicholas, MacSweeney, Cliona, Milne, Rachel, Mort, Chris, Presland, Jeremy, Sloan, Hazel, Thomson, Fiona, Turnbull, Zara, Young, Trevor

“…The discovery of a novel series of 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamide antagonists of the vasopressin V 1A receptor is disclosed…”
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discovery of novel 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamides as vasopressin V₁A receptor antagonists by Napier, Susan, Wishart, Grant, Arbuckle, William, Baker, James, Barn, David, Bingham, Matilda, Brown, Angus, Byford, Alan, Claxton, Chris, Craighead, Mark, Buchanan, Kirsteen, Fielding, Lee, Gibson, Lindsay, Goodwin, Richard, Goutcher, Susan, Irving, Nicholas, MacSweeney, Cliona, Milne, Rachel, Mort, Chris, Presland, Jeremy, Sloan, Hazel, Thomson, Fiona, Turnbull, Zara, Young, Trevor

“…The discovery of a novel series of 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamide antagonists of the vasopressin V₁A receptor is disclosed…”
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The discovery of novel 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamides as vasopressin V sub(1A receptor antagonists by Napier, Susan, Wishart, Grant, Arbuckle, William, Baker, James, Barn, David, Bingham, Matilda, Brown, Angus, Byford, Alan, Claxton, Chris, Craighead, Mark, Buchanan, Kirsteen, Fielding, Lee, Gibson, Lindsay, Goodwin, Richard, Goutcher, Susan, Irving, Nicholas, MacSweeney, Cliona, Milne, Rachel, Mort, Chris, Presland, Jeremy, Sloan, Hazel, Thomson, Fiona, Turnbull, Zara, Young, Trevor

“…The discovery of a novel series of 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamide antagonists of the vasopressin V sub(1A receptor is disclosed…”
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Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease by McLoughlin, Declan M, Irving, Nicholas G, Brownless, Janet, Brion, Jean-Pierre

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The principal's perceived effectiveness of preservice teacher training in Arizona by Clement, Nicholas Irving

“…This study investigated the principal’s perceived effectiveness of preservice teaching education and training in the state of Arizona. An in-depth interview…”
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Mouse chromosome 16 by Reeves, Roger H., Irving, Nicholas G., Miller, Robert D.

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Gene order is conserved within the human chromosome 21 linkage group on mouse chromosome 10 by Irving, N G, Cabin, D E, Swanson, D A, Reeves, R H

“…One hundred progeny from each of two intersubspecific mouse backcrosses were used to construct a comparative genetic map of a region of mouse chromosome 10…”
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The positions of 12 simple sequence repeat markers relative to reference loci on mouse chromosome 16 by Irving, N G, Citron, M P, Reeves, R H

“…The genetic map positions of 12 simple sequence repeat (SSR) markers spanning mouse Chromosome (Chr) 16 were determined relative to reference markers on that…”
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THE THEORY OF UNBIASED ESTIMATION FOR SOME NON-PARAMETRIC FAMILIES OF PROBABILITY MEASURES by FISHER, NICHOLAS IRVING

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