Search Results - "Irvine, Stewart"

Timed daily exercise remodels circadian rhythms in mice by Hughes, Alun Thomas Lloyd, Samuels, Rayna Eve, Baño-Otálora, Beatriz, Belle, Mino David Charles, Wegner, Sven, Guilding, Clare, Northeast, Rebecca Catrin, Loudon, Andrew Stewart Irvine, Gigg, John, Piggins, Hugh David

“…Regular exercise is important for physical and mental health. An underexplored and intriguing property of exercise is its actions on the body’s 24 h or…”
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Impact of a mild scrotal heat stress on DNA integrity in murine spermatozoa by Banks, Stephen, King, Sasha A, Irvine, D Stewart, Saunders, Philippa T K

“…An increase in scrotal temperature can lead to the production of poor quality spermatozoa and infertility. In the present study we have used mice to examine…”
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Serum inhibin-b in fertile men is strongly correlated with low but not high sperm counts: a coordinated study of 1,797 European and US men by Jørgensen, Niels, M.D., Ph.D, Liu, Fan, Ph.D, Andersson, Anna-Maria, Ph.D, Vierula, Matti, Ph.D, Irvine, D. Stewart, M.D., Ph.D, Auger, Jacques, M.D., Ph.D, Brazil, Charlene K., B.S, Drobnis, Erma Z., Ph.D, Jensen, Tina K., M.D., Ph.D, Jouannet, Pierre, M.D, Overstreet, James W., M.D., Ph.D, Redmon, J. Bruce, M.D, Sparks, Amy, Ph.D, Toppari, Jorma, M.D., Ph.D, Wang, Christina, M.D, Skakkebæk, Niels E., M.D, Swan, Shanna H., Ph.D

“…Objective To describe associations between serum inhibin-b and sperm counts, adjusted for effect of time of blood sampling, in larger cohorts than have been…”
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Core competencies in teaching and training for doctors in Scotland: a review of the literature and stakeholder survey by Ross, Michael T., Macrae, Claire, Scott, Jayne, Renwick, Lynne, Moffat, Mandy, Needham, Gillian, Scott, Hazel, Shippey, Ben, Jackson, Catherine, Edgar, Simon, Aitken, Debbie, Evans, Phillip, Irvine, Stewart

“…Abstract Background: The UK General Medical Council requires all registered doctors to be competent in all areas of their work, including teaching and…”
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Semen quality and spermatozoal DNA integrity in survivors of childhood cancer: a case-control study by Thomson, Angela B, Campbell, Alastair J, Irvine, D Stewart, Anderson, Richard A, Kelnar, Christopher JH, Wallace, W Hamish B

“…Treatment of childhood cancer can result in impaired spermatogenesis. Intracytoplasmic sperm injection (ICSI), however, can enable men to achieve fatherhood,…”
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How strong is the evidence of a link between environmental chemicals and adverse effects on human reproductive health? by Sharpe, Richard M, Irvine, D Stewart

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Alcohol and male reproductive health: a cross-sectional study of 8344 healthy men from Europe and the USA by Jensen, Tina Kold, Swan, Shanna, Jørgensen, Niels, Toppari, Jorma, Redmon, Bruce, Punab, Margus, Drobnis, Erma Z, Haugen, Trine Berit, Zilaitiene, Birute, Sparks, Amy E, Irvine, D Stewart, Wang, Christina, Jouannet, Pierre, Brazil, Charlene, Paasch, Uwe, Salzbrunn, Andrea, Skakkebæk, Niels Erik, Andersson, Anna-Maria

“…Is there an association between alcohol intake and semen quality and serum reproductive hormones among healthy men from the USA and Europe? Moderate alcohol…”
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Fertility preservation for young patients with cancer: who is at risk and what can be offered? by Wallace, W Hamish B, Anderson, Richard A, Irvine, D Stewart

“…Estimates suggest that by 2010, one in 715 people in the UK will have survived cancer during childhood. With increasing numbers of children cured, attention…”
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Relative Impact of Oxidative Stress on the Functional Competence and Genomic Integrity of Human Spermatozoa by AITKEN, R. J, GORDON, E, HARKISS, D, TWIGG, J. P, MILNE, P, JENNINGS, Z, IRVINE, D. S

“…Reactive oxygen metabolites are known to disrupt sperm-oocyte fusion, sperm movement, and DNA integrity; however, the relative sensitivities of these elements…”
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Reactive oxygen species generation by human spermatozoa is induced by exogenous NADPH and inhibited by the flavoprotein inhibitors diphenylene iodonium and quinacrine by Aitken, R. John, Fisher, Helen M., Fulton, Norma, Gomez, Emilio, Knox, Wendy, Lewis, Beverley, Irvine, Stewart

“…Human spermatozoa possess a specialized capacity to generate reactive oxygen species (ROS) that is thought to be of significance in the redox regulation of…”
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Regional differences in semen quality in Europe by Jørgensen, Niels, Andersen, Anne-Grethe, Eustache, Florence, Irvine, D. Stewart, Suominen, Jyrki, Petersen, Jørgen Holm, Andersen, Anders Nyboe, Auger, Jacques, Cawood, Elizabeth H.H., Horte, Antero, Jensen, Tina Kold, Jouannet, Pierre, Keiding, Niels, Vierula, Matti, Toppari, Jorma, Skakkebæk, Niels E.

“…Recent reports have indicated a decrease in semen quality of men in some countries, and suggested regional differences. A study was undertaken of semen samples…”
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Predicting the fertilizing potential of human sperm suspensions in vitro: importance of sperm morphology and leukocyte contamination by Sukcharoen, N, Keith, J, Irvine, D S, Aitken, R J

“…To determine the relationships between sperm function tests and fertilization of human oocytes in vitro. Analysis of infertile patients undergoing IVF therapy…”
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Superoxide dismutase in human sperm suspensions: Relationship with cellular composition, oxidative stress, and sperm function by Aitken, R.John, Buckingham, Donna W., Carreras, Alfonso, Stewart Irvine, D

“…Sensitive techniques have been developed for monitoring superoxide dismutase (SOD) activities inhuman sperm preparations. In contradiction to the protective…”
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Integrating new tests of sperm genetic integrity into semen analysis: breakout group discussion by Perreault, Sally D, Aitken, R John, Baker, H W Gordon, Evenson, Donald P, Huszar, Gabor, Irvine, D Stewart, Morris, Ian D, Morris, Rebecca A, Robbins, Wendie A, Sakkas, Denny, Spano, Marcello, Wyrobek, Andrew J

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Male Infertility and DNA Damage in Doppel Knockout and Prion Protein/Doppel Double-Knockout Mice by Paisley, Derek, Banks, Stephen, Selfridge, Jim, McLennan, Neil F., Ritchie, Ann-Marie, McEwan, Carolanne, Irvine, D. Stewart, Saunders, Philippa T.K., Manson, Jean C., Melton, David W.

“…The prion protein (PrP) and Doppel (Dpl) have many structural and biochemical properties in common, leading to the suggestion that the lack of an obvious…”
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The value of adenosine triphosphate (ATP) measurements in assessing the fertilizing ability of human spermatozoa by Irvine, D S, Aitken, R J

“…A study was undertaken to examine the relationship between adenosine triphosphate (ATP) levels and the fertilizing capacity of human spermatozoa in vitro and…”
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Evidence of deteriorating semen quality in the United Kingdom: birth cohort study in 577 men in Scotland over 11 years by Irvine, Stewart, Cawood, Elizabeth, Richardson, David, MacDonald, Eileen, Aitken, John

“…Abstract Objective: To determine whether the quality of semen has changed in a group of over 500 Scottish men born between 1951 and 1973. Design: Retrospective…”
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Analysis of the impact of intracellular reactive oxygen species generation on the structural and functional integrity of human spermatozoa: lipid peroxidation, DNA fragmentation and effectiveness of antioxidants by Twigg, J, Fulton, N, Gomez, E, Irvine, D S, Aitken, R J

“…Exposure of human spermatozoa to nicotinamide adenine dinucleotide phosphate (NADPH) resulted in the dose dependent generation of reactive oxygen species (ROS)…”
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Adenosine triphosphate in human semen: a quantitative estimate of fertilizing potential by Comhaire, F, Vermeulen, L, Ghedira, K, Mas, J, Irvine, S, Callipolitis, G

“…The concentration of adenosine triphosphate (ATP) per milliliter of ejaculate was found to be significantly correlated with the following parameters: sperm…”
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Relative Impact of Oxidative Stress on the Functional Competence and Genomic Integrity of Human Spermatozoa1 by Aitken, R. John, Gordon, Emma, Harkiss, Diana, Twigg, Jeremy P., Milne, Philip, Jennings, Zoë, Irvine, D. Stewart

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