Search Results - "Irvine, E. A."

The dependence of contrail formation on the weather pattern and altitude in the North Atlantic by Irvine, E. A., Hoskins, B. J., Shine, K. P.

“…Aircraft flying through cold ice‐supersaturated air produce persistent contrails which contribute to the climate impact of aviation. Here, we demonstrate the…”
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A simple framework for assessing the trade-off between the climate impact of aviation carbon dioxide emissions and contrails for a single flight by A Irvine, E, J Hoskins, B, P Shine, K

“…Persistent contrails are an important climate impact of aviation which could potentially be reduced by re-routing aircraft to avoid contrailing; however this…”
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Ice supersaturation and the potential for contrail formation in a changing climate by Irvine, E. A, Shine, K. P

“…Ice supersaturation (ISS) in the upper troposphere and lower stratosphere is important for the formation of cirrus clouds and long-lived contrails. Cold ISS…”
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Aircraft routing with minimal climate impact: the REACT4C climate cost function modelling approach (V1.0) by Grewe, V, Frömming, C, Matthes, S, Brinkop, S, Ponater, M, Dietmüller, S, Jöckel, P, Garny, H, Tsati, E, Dahlmann, K, Søvde, O. A, Fuglestvedt, J, Berntsen, T. K, Shine, K. P, Irvine, E. A, Champougny, T, Hullah, P

“…In addition to CO2, the climate impact of aviation is strongly influenced by non-CO2 emissions, such as nitrogen oxides, influencing ozone and methane, and…”
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CCN3 – A key regulator of the hematopoietic compartment by McCallum, L, Irvine, A.E

“…Summary CCN3, a founding member of the CCN family of growth regulators, was linked with hematology in 2003 when it was detected in human serum. CCN3 is…”
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Increased apoptotic peripheral blood neutrophils in systemic lupus erythematosus: relations with disease activity, antibodies to double stranded DNA, and neutropenia by Courtney, P A, Crockard, A D, Williamson, K, Irvine, A E, Kennedy, R J, Bell, A L

“…OBJECTIVE To quantify the percentage of apoptotic peripheral blood neutrophils in systemic lupus erythematosus (SLE) and to determine the relations with…”
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Can 4D‐Var use dynamical information from targeted observations of a baroclinic structure? by Irvine, E. A., Gray, S. L., Methven, J.

“…Targeted observations are generally taken in regions of high baroclinicity, but often show little impact. One plausible explanation is that important dynamical…”
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Enhanced lymphocyte interferon (IFN)‐γ responses in a PTEN mutation‐negative Cowden disease kindred by Stevenson, R., Fatehullah, A., Jagan, I., Deevi, R. K., Bingham, V., Irvine, A. E., Armstrong, M., Morrison, P. J., Dimmick, I., Stewart, R., Campbell, F. C.

“…Summary Identification of immune modifiers of inherited cancer syndromes may provide a rationale for preventive therapy. Cowden disease (CD) is a genetically…”
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A Lagrangian analysis of ice-supersaturated air over the North Atlantic by Irvine, E. A., Hoskins, B. J., Shine, K. P.

“…Understanding the nature of air parcels that exhibit ice supersaturation is important because they are the regions of potential formation of both cirrus and…”
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High bax expression is a good prognostic indicator in acute myeloid leukaemia by ONG, Y. L, MCMULLIN, M. F, BAILIE, K. E. M, LAPPIN, T. R. J, JONES, F. G. C, IRVINE, A. E

“…Most cytotoxic drugs kill cells by instigating the process of apoptosis and it has been suggested that apoptotic markers may provide an indication of tumour…”
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Analysis of the effect of prior therapy on progenitor cell yield: use of a chemotherapy scoring system by Drake, M., Ranaghan, L., Morris, T. C. M., Nolan, L., Desai, Z. R., Irvine, A. E., Jordan, A., Magill, K., Price, S.

“…A quantitative analysis of peripheral blood stem cell (PBSC) yield, measuring absolute numbers of CD34+ cells × 106/kg and CFU‐C × 104/kg was performed in 74…”
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Targeted observations of a polar low in the Norwegian Sea by Irvine, E. A., Gray, S. L., Methven, J.

“…A developing polar low is targeted with dropsonde observations to improve the forecast of its landfall. Accurately forecasting a polar low's strength and…”
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Methods for measuring proteasome activity: Current limitations and future developments by Liggett, A, Crawford, L.J, Walker, B, Morris, T.C.M, Irvine, A.E

“…Abstract The proteasome has been validated as a therapeutic target, with proteasome inhibitors showing particular efficacy in the treatment of Multiple…”
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Synergistic effects of proteasome inhibitor carfilzomib in combination with tyrosine kinase inhibitors in imatinib-sensitive and -resistant chronic myeloid leukemia models by Crawford, L J, Chan, E T, Aujay, M, Holyoake, T L, Melo, J V, Jorgensen, H G, Suresh, S, Walker, B, Irvine, A E

“…The tyrosine kinase inhibitor (TKI) imatinib has transformed the treatment and outlook of chronic myeloid leukemia (CML); however, the development of drug…”
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Prognostic value of C-reactive protein and cytokine assays for transplant-related mortality by Morris, T C M, Magill, M K, Ranaghan, L, Irvine, A E

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Granulocyte and granulocyte-macrophage colony-stimulating factors in cord and maternal serum at delivery by BAILIE, K. E. M, IRVINE, A. E, BRIDGES, J. M, MCCLURE, B. G

“…Impaired neutrophil responses contribute to the neonate's increased susceptibility to infection. Because granulocyte colony-stimulating factor (G-CSF) and…”
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Human blood and synovial fluid neutrophils cultured in vitro undergo programmed cell death which is promoted by the addition of synovial fluid by Bell, A L, Magill, M K, McKane, R, Irvine, A E

“…OBJECTIVE--To assess the influence of inflammatory synovial fluid (SF) on apoptosis of joint and blood neutrophils with particular reference to levels of…”
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Fate of inflammatory neutrophils within the joint by Bell, A. L., Irvine, A. E., Magill, K., McKane, R.

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The impact of targeted observations made during the Greenland Flow Distortion Experiment by Irvine, E. A., Gray, S. L., Methven, J., Renfrew, I. A., Bovis, K., Swinbank, R.

“…The impact of targeted sonde observations on the 1‐3 day forecasts for northern Europe is evaluated using the Met Office four‐dimensional variational data…”
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THE GREENLAND FLOW DISTORTION EXPERIMENT by Renfrew, I. A., Moore, G. W. K., Kristjánsson, J. E., Ólafsson, H., Gray, S. L., Petersen, G. N., Bovis, K., Brown, P. R. A., Føre, I., Haine, T., Hay, C., Irvine, E. A., Lawrence, A., Ohigashi, T., Outten, S., Pickart, R. S., Shapiro, M., Sproson, D., Swinbank, R., Woolley, A., Zhang, S.

“…Greenland has a major influence on the atmospheric circulation of the North Atlantic–western European region, dictating the location and strength of mesoscale…”
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