Search Results - "Irvine, A."

Severe COVID-19 Infection and Pediatric Comorbidities: A Systematic Review and Meta-Analysis by Tsankov, Boyan K., Allaire, Joannie M., Irvine, Michael A., Lopez, Alison A., Sauvé, Laura J., Vallance, Bruce A., Jacobson, Kevan

“…What is known •Adults with comorbidities are more likely to suffer from severe manifestations of COVID-19•Children with COVID-19 have less severe disease…”
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Remyelination protects axons from demyelination-associated axon degeneration by Irvine, K. A., Blakemore, W. F.

“…In multiple sclerosis, demyelination of the CNS axons is associated with axonal injury and degeneration, which is now accepted as the major cause of…”
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Targeting hedgehog in hematologic malignancy by Irvine, David A., Copland, Mhairi

“…The Hedgehog pathway is a critical mediator of embryonic patterning and organ development, including hematopoiesis. It influences stem cell fate,…”
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An open resource for accurately benchmarking small variant and reference calls by Zook, Justin M., McDaniel, Jennifer, Olson, Nathan D., Wagner, Justin, Parikh, Hemang, Heaton, Haynes, Irvine, Sean A., Trigg, Len, Truty, Rebecca, McLean, Cory Y., De La Vega, Francisco M., Xiao, Chunlin, Sherry, Stephen, Salit, Marc

“…Benchmark small variant calls are required for developing, optimizing and assessing the performance of sequencing and bioinformatics methods. Here, as part of…”
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Systemic and stratum corneum biomarkers of severity in infant atopic dermatitis include markers of innate and T helper cell‐related immunity and angiogenesis by McAleer, M.A., Jakasa, I., Hurault, G., Sarvari, P., McLean, W.H.I., Tanaka, R.J., Kezic, S., Irvine, A.D.

“…Summary Background Biomarkers of atopic dermatitis (AD) are largely lacking, especially in infant AD. Those that have been examined to date have focused mostly…”
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Bioprinting and Differentiation of Stem Cells by Irvine, Scott A, Venkatraman, Subbu S

“…The 3D bioprinting of stem cells directly into scaffolds offers great potential for the development of regenerative therapies; in particular for the…”
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Disease trajectories in childhood atopic dermatitis: an update and practitioner's guide by Irvine, A.D., Mina‐Osorio, P.

“…Summary Background Atopic dermatitis (AD) is a heterogeneous disease with a multifactorial aetiology and complex pathophysiology. This heterogeneity translates…”
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Electrical manipulation of ferromagnetic NiFe by antiferromagnetic IrMn by Tshitoyan, V., Ciccarelli, C., Mihai, A. P., Ali, M., Irvine, A. C., Moore, T. A., Jungwirth, T., Ferguson, A. J.

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Disorders of compulsivity: a common bias towards learning habits by Voon, V, Derbyshire, K, Rück, C, Irvine, M A, Worbe, Y, Enander, J, Schreiber, L R N, Gillan, C, Fineberg, N A, Sahakian, B J, Robbins, T W, Harrison, N A, Wood, J, Daw, N D, Dayan, P, Grant, J E, Bullmore, E T

“…Why do we repeat choices that we know are bad for us? Decision making is characterized by the parallel engagement of two distinct systems, goal-directed and…”
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Levels of filaggrin degradation products are influenced by both filaggrin genotype and atopic dermatitis severity by Kezic, S., O’Regan, G. M., Yau, N., Sandilands, A., Chen, H., Campbell, L. E., Kroboth, K., Watson, R., Rowland, M., Irwin McLean, W. H., Irvine, A. D.

“…To cite this article: Kezic S, O’Regan GM, Yau N, Sandilands A, Chen H, Campbell LE, Kroboth K, Watson R, Rowland M, Irwin McLean WH, Irvine AD. Levels of…”
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Use of systemic corticosteroids for atopic dermatitis: International Eczema Council consensus statement by Drucker, A.M., Eyerich, K., de Bruin‐Weller, M.S., Thyssen, J.P., Spuls, P.I., Irvine, A.D., Girolomoni, G., Dhar, S., Flohr, C., Murrell, D.F., Paller, A.S., Guttman‐Yassky, E.

“…Summary Background Guidelines discourage the use of systemic corticosteroids for atopic dermatitis (AD), but their use remains widespread. Objectives To reach…”
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The role of bacterial skin infections in atopic dermatitis: expert statement and review from the International Eczema Council Skin Infection Group by Alexander, H., Paller, A.S., Traidl‐Hoffmann, C., Beck, L.A., De Benedetto, A., Dhar, S., Girolomoni, G., Irvine, A.D., Spuls, P., Su, J., Thyssen, J.P., Vestergaard, C., Werfel, T., Wollenberg, A., Deleuran, M., Flohr, C.

“…Summary Patients with atopic dermatitis (AD) have an increased risk of bacterial skin infections, which cause significant morbidity and, if untreated, may…”
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The NLRP3 inflammasome functions as a driver of the myelodysplastic syndrome phenotype by Basiorka, Ashley A., McGraw, Kathy L., Eksioglu, Erika A., Chen, Xianghong, Johnson, Joseph, Zhang, Ling, Zhang, Qing, Irvine, Brittany A., Cluzeau, Thomas, Sallman, David A., Padron, Eric, Komrokji, Rami, Sokol, Lubomir, Coll, Rebecca C., Robertson, Avril A.B., Cooper, Matthew A., Cleveland, John L., O'Neill, Luke A., Wei, Sheng, List, Alan F.

“…Despite genetic heterogeneity, myelodysplastic syndromes (MDSs) share features of cytological dysplasia and ineffective hematopoiesis. We report that a…”
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The role of filaggrin in the atopic diathesis by O'Regan, G. M., Irvine, A. D.

“…Summary Atopic dermatitis (AD) is an inflammatory disease characterized by pruritic skin lesions, immunodysregulation, disrupted epidermal barrier function and…”
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Machine intelligence identifies soluble TNFa as a therapeutic target for spinal cord injury by Huie, J. R., Ferguson, A. R., Kyritsis, N., Pan, J. Z., Irvine, K.-A., Nielson, J. L., Schupp, P. G., Oldham, M. C., Gensel, J. C., Lin, A., Segal, M. R., Ratan, R. R., Bresnahan, J. C., Beattie, M. S.

“…Traumatic spinal cord injury (SCI) produces a complex syndrome that is expressed across multiple endpoints ranging from molecular and cellular changes to…”
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The use of mixture density networks in the emulation of complex epidemiological individual-based models by Davis, Christopher N, Hollingsworth, T Deirdre, Caudron, Quentin, Irvine, Michael A

“…Complex, highly-computational, individual-based models are abundant in epidemiology. For epidemics such as macro-parasitic diseases, detailed modelling of…”
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A novel 3D printing method for cell alignment and differentiation by Bhuthalingam, Ramya, Lim, Pei Qi, A Irvine, Scott, Agrawal, Animesh, Mhaisalkar, Priyadarshini S, An, Jia, Chua, Chee Kai, Venkatraman, Subbu

“…The application of bioprinting allows precision deposition of biological materials for bioengineering applications. Here we propose a 2 stage methodology for…”
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Mobile-Web app to self-manage low back pain: randomized controlled trial by Irvine, A Blair, Russell, Holly, Manocchia, Michael, Mino, David E, Cox Glassen, Terri, Morgan, Rebecca, Gau, Jeff M, Birney, Amelia J, Ary, Dennis V

“…Nonspecific low back pain (NLBP) is the diagnosis for individuals with back pain that has no underlying medical cause (eg, tumor, infection, fracture,…”
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Observed negative vaccine effectiveness could be the canary in the coal mine for biases in observational COVID-19 studies by Bodner, Korryn, Irvine, Michael A., Kwong, Jeffrey C., Mishra, Sharmistha

“…•Negative vaccine effectiveness (VE) has been reported for COVID-19.•These measurements likely stem from various biases.•Negative VE signals that estimates…”
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An antidamping spin–orbit torque originating from the Berry curvature by Kurebayashi, H., Sinova, Jairo, Fang, D., Irvine, A. C., Skinner, T. D., Wunderlich, J., Novák, V., Campion, R. P., Gallagher, B. L., Vehstedt, E. K., Zârbo, L. P., Výborný, K., Ferguson, A. J., Jungwirth, T.

“…Magnetization switching at the interface between ferromagnetic and paramagnetic metals, controlled by current-induced torques, could be exploited in magnetic…”
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