Search Results - "Irshad, Rasha"
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Curcumin decreases Warburg effect in cancer cells by down-regulating pyruvate kinase M2 via mTOR-HIF1α inhibition
Published in Scientific reports (29-05-2018)“…Warburg effect is an emerging hallmark of cancer cells with pyruvate kinase M2 (PKM2) as its key regulator. Curcumin is an extensively-studied anti-cancer…”
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Integrated network pharmacology and experimental analysis unveil multi-targeted effect of 18α- glycyrrhetinic acid against non-small cell lung cancer
Published in Frontiers in pharmacology (12-10-2022)“…Non-small cell lung cancer (NSCLC) is one of the most malignant types of cancer with soaring incidence rates worldwide, attributed to its heterogeneity and…”
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Natural products in the reprogramming of cancer epigenetics
Published in Toxicology and applied pharmacology (15-04-2021)“…Owing to the technological advancements, including next generation sequencing, the significance of deregulated epigenetic mechanisms in cancer initiation,…”
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Multi-targeted effects of D-carvone against Non-Small Cell Lung Cancer (NSCLC): A network pharmacology-based study
Published in Toxicology and applied pharmacology (01-06-2024)“…Non-small cell lung cancer (NSCLC) is a complex malignancy with a high degree of heterogeneity, representing approximately 85% of all lung cancer cases. The…”
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TLRs in pulmonary diseases
Published in Life sciences (1973) (15-09-2019)“…Toll-like receptors (TLRs) comprise a clan of proteins involved in identification and triggering a suitable response against pathogenic attacks. As lung is…”
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