Search Results - "Irshad, Khushboo"

Molecular basis of hepatocellular carcinoma induced by hepatitis C virus infection by Irshad, Mohammad, Gupta, Priyanka, Irshad, Khushboo

“…Present study outlines a comprehensive view of published information about the underlying mechanisms operational for progression of chronic hepatitis C…”
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Receptor tyrosine kinase gene expression profiling of orbital rhabdomyosarcoma unveils MET as a potential biomarker and therapeutic target by Chauhan, Sheetal, Sen, Seema, Irshad, Khushboo, Kashyap, Seema, Pushker, Neelam, Meel, Rachna, Sharma, Mehar Chand

“…Receptor tyrosine kinases (RTKs) serve as molecular targets for the development of novel personalized therapies in many malignancies. In the present study,…”
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Upregulation of Atypical Cadherin FAT1 Promotes an Immunosuppressive Tumor Microenvironment via TGF-β by Irshad, Khushboo, Srivastava, Chitrangda, Malik, Nargis, Arora, Manvi, Gupta, Yakhlesh, Goswami, Sanjeev, Sarkar, Chitra, Suri, Vaishali, Mahajan, Swati, Gupta, Deepak Kumar, Suri, Ashish, Chattopadhyay, Parthaprasad, Sinha, Subrata, Chosdol, Kunzang

“…FAT atypical cadherin 1 (FAT1) promotes glioblastoma (GBM) by promoting protumorigenic inflammatory cytokine expression in tumor cells. However, tumors also…”
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A combined gene signature of hypoxia and notch pathway in human glioblastoma and its prognostic relevance by Irshad, Khushboo, Mohapatra, Saroj Kant, Srivastava, Chitrangda, Garg, Harshit, Mishra, Seema, Dikshit, Bhawana, Sarkar, Chitra, Gupta, Deepak, Chandra, Poodipedi Sarat, Chattopadhyay, Parthaprasad, Sinha, Subrata, Chosdol, Kunzang

“…Hypoxia is a hallmark of solid tumors including glioblastoma (GBM). Its synergism with Notch signaling promotes progression in different cancers. However,…”
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The quest for ligands and binding partners of atypical cadherin FAT1 by Irshad, Khushboo, Malik, Nargis, Arora, Manvi, Gupta, Yakhlesh, Sinha, Subrata, Chosdol, Kunzang

“…A recent study in Scientific Reports identified glypican-3 (GPC3) as a novel extracellular interacting protein for FAT1 in hepato-cellular carcinoma (HCC)…”
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NFкB is a critical transcriptional regulator of atypical cadherin FAT1 in glioma by Srivastava, Chitrangda, Irshad, Khushboo, Gupta, Yakhlesh, Sarkar, Chitra, Suri, Ashish, Chattopadhyay, Parthaprasad, Sinha, Subrata, Chosdol, Kunzang

“…Overexpression of FAT1 gene and its oncogenic effects have been reported in several cancers. Previously, we have documented upregulation of FAT1 gene in…”
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The Neuroimmune Regulation and Potential Therapeutic Strategies of Optic Pathway Glioma by Irshad, Khushboo, Huang, Yu-Kai, Rodriguez, Paul, Lo, Jung, Aghoghovwia, Benjamin E, Pan, Yuan, Chang, Kun-Che

“…Optic pathway glioma (OPG) is one of the causes of pediatric visual impairment. Unfortunately, there is as yet no cure for such a disease. Understanding the…”
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Torque teno virus： Its prevalence and isotypes in North India by Irshad, Mohammad, Singh, Shiwani, Irshad, Khushboo, Agarwal, Sanjay-Kumar, Joshi, Yogendra-Kumar

“…AIM： To investigate the prevalence and genotype distribution of Torque teno virus （TTV） in patients with different liver diseases and chronic renal failure…”
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An insight into the diagnosis and pathogenesis of hepatitis C virus infection by Irshad, Mohammad, Mankotia, Dhananjay Singh, Irshad, Khushboo

“…This review focuses on research findings in the area of diagnosis and pathogenesis of hepatitis C virus (HCV) infection over the last few decades. The…”
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FAT1 modulates EMT and stemness genes expression in hypoxic glioblastoma by Srivastava, Chitrangda, Irshad, Khushboo, Dikshit, Bhawana, Chattopadhyay, Parthaprasad, Sarkar, Chitra, Gupta, Deepak Kumar, Sinha, Subrata, Chosdol, Kunzang

“…Glioblastoma (GBM) is characterized by the presence of hypoxia, stemness and local invasiveness. We have earlier demonstrated that FAT1 promotes invasiveness,…”
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CNSC-18. DIFFERENTIAL EFFECTS OF NEUROTRANSMITTERS ON THE GROWTH OF GLIOBLASTOMA SUBTYPES by Irshad, Khushboo, Singh, Sanjay, Ahmad, Khalil Ali, Aghoghovwia, Ben, Alnassiry, Sama, Lang, Frederick, Pan, Yuan

“…Abstract Glioblastomas are aggressive brain tumors associated with the worst patient prognosis. Neurons play critical roles in modulating the growth of…”
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The role of ALDH1A1 in glioblastoma proliferation and invasion by Huang, Yu-Kai, Wang, Tzu-Ming, Chen, Chi-Yu, Li, Chia-Yang, Wang, Shu-Chi, Irshad, Khushboo, Pan, Yuan, Chang, Kun-Che

“…High-grade gliomas, including glioblastoma multiforme (GBM), continue to be a leading aggressive brain tumor in adults, marked by its rapid growth and invasive…”
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Protumorigenic role of the atypical cadherin FAT1 by the suppression of PDCD10 via RelA/miR221‐3p/222‐3p axis in glioblastoma by Malik, Nargis, Kundu, Archismita, Gupta, Yakhlesh, Irshad, Khushboo, Arora, Manvi, Goswami, Sanjeev, Mahajan, Swati, Sarkar, Chitra, Suri, Vaishali, Suri, Ashish, Chattopadhyay, Parthaprasad, Sinha, Subrata, Chosdol, Kunzang

“…Abstract The atypical cadherin FAT1 function either as a pro or antitumorigenic in tumors of different tissue origins. Our group previously demonstrated the…”
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CNSC-13. CROSSTALK BETWEEN SENSORY NEURONAL ACTIVITY AND TUMOR CELLS PROMOTES MALIGNANCY AND CANCER PAIN by Ahmad Kasm, Khalil Ali, Ban, Kechen, Irshad, Khushboo, Cortez, Ibdanelo, Shen, Cheng-En, Singh, Anand, Rasheed, Sami Mohd, Willcox, Kendal, Grace, Peter M, Hirbe, Angela, Shepherd, Andrew J, Pan, Yuan

“…Abstract BACKGROUND Nerve infiltration of solid tumors is associated with poor prognosis in multiple cancer types. Understanding the role of neuronal activity…”
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TMIC-18. ROLE OF NEUROTRANSMITTERS IN GLIOBLASTOMA PATHOPHYSIOLOGY: EMERGING INSIGHTS by Irshad, Khushboo, Singh, Sanjay, Ahmad, Khalil Ali, Ban, Kechen, Aghoghovwia, Benjamin, Mahalingam, Rajasekaran, Harris, Momo, Alnassiry, Sama, Bertrand, Renae, Gargapati, Aishani, Bui, Nathan, Kuo, Truc, Lang, Frederick, Pan, Yuan

“…Abstract INTRODUCTION Glioblastoma (GBM) are the most common primary brain tumor in adults associated with a dismal patient outcome. While it is well-known…”
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Abstract 3175: FAT1 and the immunosuppressive milieu in glioblastoma tumors by Irshad, Khushboo, Srivastava, Chitrangda, Malik, Nargis, Gupta, Yakhlesh, Suri, Vaishali, Mahajan, Swati, Gupta, Deepak, Suri, Ashish, Chattopadhyay, Parthaprasad, Sinha, Subrata, Chosdol, Kunzang

“…Abstract INTRODUCTION: Glioblastoma tumors harbor an immunosuppressive microenvironment which is sustained by key players such as TGF-β1/2 and IL-10 cytokines;…”
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NFкB is a critical transcriptional regulator of atypical cadherin FAT1 in glioma by Srivastava, Chitrangda, Irshad, Khushboo, Gupta, Yakhlesh, Sarkar, Chitra, Suri, Ashish, Chattopadhyay, Parthaprasad, Sinha, Subrata, Chosdol, Kunzang

“…Background Overexpression of FAT1 gene and its oncogenic effects have been reported in several cancers. Previously, we have documented upregulation of FAT1…”
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Hypoxia on Notch Signalling, Epithelialmesenchymal Transition and Stemness in Glioblastoma by Chosdol, Kunzang, Irshad, Khushboo, Srivastava, Chitrangda, Mohapatra, Saroj, Sarkar, Chitra, Chandra, P.S, Gupta, Deepak, Sinha, Subrata

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Single Nucleotide Polymorphisms of Folate Metabolizing Enzymes and their Association with Brain Tumors by Kumawat, Rajani, Malik, Ekta, Rashid, Safoora, Irshad, Khushboo, Suri, Ashish, Sinha, Subrata, Chosdol, Kunzang

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Abstract 3534: FAT1: A potential target of NFkB (RelA) in GBM by Srivastava, Chitrangda, Irshad, Khushboo, Chattopadhyay, Parthaprasad, Sarkar, Chitra, Suri, Ashish, Sinha, Subrata, Chosdol, Kunzang

“…Abstract FAT1 is a large transmembrane protein (502 kD), reportedly having dual role in different human cancers. Our lab has reported oncogenic role of FAT1…”
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