Search Results - "Irfan Shaukat"

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    Atraumatic splenic rupture due to covid-19 infection by Shaukat, Irfan, Khan, Raisa, Diwakar, Lavanya, Kemp, Timothy, Bodasing, Neena

    Published in Clinical infection in practice (01-04-2021)
    “…Covid-19 is a novel disease caused by the severe acute respiratory coronavirus (SARS-CoV2). We discuss a gentleman who presented with an atraumatic rupture of…”
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    Journal Article
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    Blessing in disguise; a case of Hereditary Persistence of Fetal Hemoglobin by Shaukat, Irfan, Pudal, Amrit, Yassin, Sayf, Höti, Naseruddin, Mustafa, Sadaf

    “…Fetal Hemoglobin (HbF, α2γ2) is produced from the eighth week of gestation, constitutes 60 - 80 % of total hemoglobin by birth, which is then replaced with…”
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    Journal Article
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    Unusual presentation of parasitic leiomyoma; a tale of twists and turns by Shaukat, Irfan, Yassin, Sayf, Paudel, Amrit, Höti, Naseruddin, Mustafa, Sadaf

    “…Uterine leiomyoma is the most common benign pelvic tumor of the myometrium, as the prevalence could be as high as 70%. Major risk factors include age between…”
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    Aggressive Metastatic GATA3-Positive Sarcomatoid Carcinoma with Rapid Progression and Invasion of the Liver by Höti, Naseruddin, Inayat, Maimoona, Padgett, Charles, Shaukat, Irfan, Mustafa, Sadaf

    Published in Case reports in oncological medicine (01-01-2018)
    “…Objective. GATA3-positive sarcomatoid carcinoma has never been documented in the past. It is a case of aggressive tumor, positive for GATA3, which should be…”
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    Journal Article
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    A di‐arginine‐based ER retention motif regulates the stability and maturation of NKCC2 and its disease causing mutants by Shaukat, Irfan, Demartez, Sylvie, Laghmani, Kamel

    Published in The FASEB journal (01-04-2019)
    “…Mutations in the apically located Na‐K‐2Cl cotransporter, NKCC2, lead to type I Bartter syndrome, a life‐threatening kidney disease. Yet very little is known…”
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    Non-canonical Wnt induces chondrocyte de-differentiation through Frizzled 6 and DVL-2/B-raf/CaMKIIα/syndecan 4 axis by Xie, Zhe, Khair, Mostafa, Shaukat, Irfan, Netter, Patrick, Mainard, Didier, Barré, Lydia, Ouzzine, Mohamed

    Published in Cell death and differentiation (01-08-2018)
    “…Dysregulation of Wnt signaling has been implicated in developmental defects and in the pathogenesis of many diseases such as osteoarthritis; however, the…”
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    Journal Article
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    Ginsenoside Rb1 ameliorates Staphylococcus aureus-induced Acute Lung Injury through attenuating NF-κB and MAPK activation by Shaukat, Aftab, Guo, Ying-fang, Jiang, Kangfeng, Zhao, Gan, Wu, Haichong, Zhang, Tao, Yang, Yaping, Guo, Shuai, Yang, Chao, Zahoor, Arshad, Akhtar, Muhammad, Umar, Talha, Shaukat, Irfan, Rajput, Shahid Ali, Hassan, Mubashar, Deng, Ganzhen

    Published in Microbial pathogenesis (01-07-2019)
    “…Acute lung injury (ALI) is clinically characterized by excessive inflammation leading to acute respiratory distress syndrome (ARDS), having high morbidity and…”
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    Therapeutic administration of Luteolin protects against Escherichia coli-derived Lipopolysaccharide-triggered inflammatory response and oxidative injury by Shaukat, Aftab, Rajput, Shahid Ali, Ali, Mehboob, Shukat, Rizwan, Hanif, Sana, Hassan, Mubashar, Fouad, Dalia, Ataya, Farid S., Shaukat, Irfan, Yousaf, Arfan, Shaukat, Shadab, Su, Ren-Wei

    Published in Acta tropica (01-07-2024)
    “…•Endometritis is an inflammatory condition affecting the endometrial lining of the uterus.•LPS could exacerbate oxidative injury and inflammatory reactions in…”
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    Estimation of serum iron, serum lipids and serum liver enzymes in celiac disease patients of Saudi Arabia by Ikram Ullah, Muhammad, Alsrhani, Abdullah, Atif, Muhammad, Shaukat, Irfan, Hussain, Shahid, Ejaz, Hasan

    Published in Pakistan journal of medical sciences (31-12-2022)
    “…Objectives: To evaluate the serum biochemical levels in celiac disease (CD) patients. Methods: It was a cross-sectional study carried out on 70 subjects,…”
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    New insights into the role of endoplasmic reticulum‐associated degradation in Bartter Syndrome Type 1 by Shaukat, Irfan, Bakhos‐Douaihy, Dalal, Zhu, Yingying, Seaayfan, Elie, Demaretz, Sylvie, Frachon, Nadia, Weber, Stefanie, Kömhoff, Martin, Vargas‐Poussou, Rosa, Laghmani, Kamel

    Published in Human mutation (01-08-2021)
    “…Mutations in Na‐K‐2Cl co‐transporter, NKCC2, lead to type I Bartter syndrome (BS1), a life‐threatening kidney disease. Yet, our knowledge of the molecular…”
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    Journal Article
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    Constitutive activation of EGFR is associated with tumor progression and plays a prominent role in malignant phenotype of chondrosarcoma by Qin, Jun, Shaukat, Irfan, Mainard, Didier, Netter, Patrick, Barré, Lydia, Ouzzine, Mohamed

    Published in Oncotarget (07-05-2019)
    “…Chondrosarcoma is a highly agressive cancer with currently no effective therapies when unresectable or metastasized, thus the outcome remains poor. High-grade…”
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    Targeting of Proteoglycan Synthesis Pathway: A New Strategy to Counteract Excessive Matrix Proteoglycan Deposition and Transforming Growth Factor-beta 1-Induced Fibrotic Phenotype in Lung Fibroblasts by Shaukat, Irfan, Barre, Lydia, Venkatesan, Narayanan, Li, Dong, Jaquinet, Jean-Claude, Fournel-Gigleux, Sylvie, Ouzzine, Mohamed

    Published in PloS one (11-01-2016)
    “…Stimulation of proteoglycan (PG) synthesis and deposition plays an important role in the pathophysiology of fibrosis and is an early and dominant feature of…”
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