Search Results - "Irfan Shaukat"
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Icariin Alleviates Escherichia coli Lipopolysaccharide-Mediated Endometritis in Mice by Inhibiting Inflammation and Oxidative Stress
Published in International journal of molecular sciences (06-09-2022)“…Icariin (ICA) is a naturally occurring phytochemical agent primarily extracted from Epimedium Brevicornum Maxim (Family Berberidaceae) with a broad spectrum of…”
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Ginsenoside Rb1 protects from Staphylococcus aureus-induced oxidative damage and apoptosis through endoplasmic reticulum-stress and death receptor-mediated pathways
Published in Ecotoxicology and environmental safety (01-08-2021)“…Acute lung injury (ALI) is acute uncontrolled inflammation of lung tissue that leads to high fatality both in human and animals. Staphylococcus aureus (S…”
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Ginsenoside Rb1 Mitigates Escherichia coli Lipopolysaccharide-Induced Endometritis through TLR4-Mediated NF-κB Pathway
Published in Molecules (Basel, Switzerland) (23-11-2021)“…Endometritis is the inflammatory response of the endometrial lining of the uterus and is associated with low conception rates, early embryonic mortality, and…”
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Atraumatic splenic rupture due to covid-19 infection
Published in Clinical infection in practice (01-04-2021)“…Covid-19 is a novel disease caused by the severe acute respiratory coronavirus (SARS-CoV2). We discuss a gentleman who presented with an atraumatic rupture of…”
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Biogenic synthesis of MoO3 nanoparticles using extract of Lactuca Serriola plant of Asteraceous flora: palynomorphological studies and environmental remediation applications
Published in Journal of Taibah University for Science (31-12-2024)“…The development of environmental remedies using ecofriendly and green technologies is attracting increasing research attention. Herein, the green synthesis of…”
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Self-Emulsifying Drug Delivery Systems (SEDDS): Measuring Energy Dynamics to Determine Thermodynamic and Kinetic Stability
Published in Pharmaceuticals (Basel, Switzerland) (26-08-2022)“…This research was designed to identify thermodynamically and kinetically stable lipidic self-emulsifying formulations through simple energy dynamics in…”
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Targeting of Proteoglycan Synthesis Pathway: A New Strategy to Counteract Excessive Matrix Proteoglycan Deposition and Transforming Growth Factor-β1-Induced Fibrotic Phenotype in Lung Fibroblasts
Published in PloS one (2016)“…Stimulation of proteoglycan (PG) synthesis and deposition plays an important role in the pathophysiology of fibrosis and is an early and dominant feature of…”
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Blessing in disguise; a case of Hereditary Persistence of Fetal Hemoglobin
Published in Journal of community hospital internal medicine perspectives (02-11-2018)“…Fetal Hemoglobin (HbF, α2γ2) is produced from the eighth week of gestation, constitutes 60 - 80 % of total hemoglobin by birth, which is then replaced with…”
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Unusual presentation of parasitic leiomyoma; a tale of twists and turns
Published in Journal of community hospital internal medicine perspectives (04-03-2019)“…Uterine leiomyoma is the most common benign pelvic tumor of the myometrium, as the prevalence could be as high as 70%. Major risk factors include age between…”
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Aggressive Metastatic GATA3-Positive Sarcomatoid Carcinoma with Rapid Progression and Invasion of the Liver
Published in Case reports in oncological medicine (01-01-2018)“…Objective. GATA3-positive sarcomatoid carcinoma has never been documented in the past. It is a case of aggressive tumor, positive for GATA3, which should be…”
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A di‐arginine‐based ER retention motif regulates the stability and maturation of NKCC2 and its disease causing mutants
Published in The FASEB journal (01-04-2019)“…Mutations in the apically located Na‐K‐2Cl cotransporter, NKCC2, lead to type I Bartter syndrome, a life‐threatening kidney disease. Yet very little is known…”
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Non-canonical Wnt induces chondrocyte de-differentiation through Frizzled 6 and DVL-2/B-raf/CaMKIIα/syndecan 4 axis
Published in Cell death and differentiation (01-08-2018)“…Dysregulation of Wnt signaling has been implicated in developmental defects and in the pathogenesis of many diseases such as osteoarthritis; however, the…”
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Ginsenoside Rb1 ameliorates Staphylococcus aureus-induced Acute Lung Injury through attenuating NF-κB and MAPK activation
Published in Microbial pathogenesis (01-07-2019)“…Acute lung injury (ALI) is clinically characterized by excessive inflammation leading to acute respiratory distress syndrome (ARDS), having high morbidity and…”
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Photocatalytic and Antibacterial activities of bio-synthesised silver nanoparticles (AgNPs) using Grewia asiatica leaves extract
Published in International journal of environmental analytical chemistry (22-12-2024)“…In this study, silver nanoparticles (AgNPs) were fabricated at room temperature using Grewia asiatica leaf extract. Photocatalytic activity (degradation of…”
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Therapeutic administration of Luteolin protects against Escherichia coli-derived Lipopolysaccharide-triggered inflammatory response and oxidative injury
Published in Acta tropica (01-07-2024)“…•Endometritis is an inflammatory condition affecting the endometrial lining of the uterus.•LPS could exacerbate oxidative injury and inflammatory reactions in…”
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Estimation of serum iron, serum lipids and serum liver enzymes in celiac disease patients of Saudi Arabia
Published in Pakistan journal of medical sciences (31-12-2022)“…Objectives: To evaluate the serum biochemical levels in celiac disease (CD) patients. Methods: It was a cross-sectional study carried out on 70 subjects,…”
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New insights into the role of endoplasmic reticulum‐associated degradation in Bartter Syndrome Type 1
Published in Human mutation (01-08-2021)“…Mutations in Na‐K‐2Cl co‐transporter, NKCC2, lead to type I Bartter syndrome (BS1), a life‐threatening kidney disease. Yet, our knowledge of the molecular…”
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Constitutive activation of EGFR is associated with tumor progression and plays a prominent role in malignant phenotype of chondrosarcoma
Published in Oncotarget (07-05-2019)“…Chondrosarcoma is a highly agressive cancer with currently no effective therapies when unresectable or metastasized, thus the outcome remains poor. High-grade…”
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Targeting of Proteoglycan Synthesis Pathway: A New Strategy to Counteract Excessive Matrix Proteoglycan Deposition and Transforming Growth Factor-beta 1-Induced Fibrotic Phenotype in Lung Fibroblasts
Published in PloS one (11-01-2016)“…Stimulation of proteoglycan (PG) synthesis and deposition plays an important role in the pathophysiology of fibrosis and is an early and dominant feature of…”
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20
Upregulated-gene expression of pro-inflammatory cytokines, oxidative stress and apoptotic markers through inflammatory, oxidative and apoptosis mediated signaling pathways in Bovine Pneumonia
Published in Microbial pathogenesis (01-06-2021)“…Pneumonia is the acute inflammation of lung tissue and is multi-factorial in etiology. Staphylococcus aureus (S. aureus) is a harmful pathogen present as a…”
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