Search Results - "Ireland, Alex W"

Chemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators by Huryn, Donna M, Brodsky, Jeffrey L, Brummond, Kay M, Chambers, Peter G, Eyer, Benjamin, Ireland, Alex W, Kawasumi, Masaoki, LaPorte, Matthew G, Lloyd, Kayla, Manteau, Baptiste, Nghiem, Paul, Quade, Bettina, Seguin, Sandlin P, Wipf, Peter

“…Unique chemical methodology enables the synthesis of innovative and diverse scaffolds and chemotypes and allows access to previously unexplored "chemical…”
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Upland deforestation triggered an ecosystem state‐shift in a kettle peatland by Ireland, Alex W., Booth, Robert K.

“…1. European settlement of eastern North America resulted in dramatic changes to ecosystems, although the dynamics and underlying causes of these changes are…”
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Rapid Delineation of Preliminary Ecological Sites Applied to Forested Northern Appalachian Landscapes by Ireland, Alex W., Drohan, Patrick J.

“…The fundamental assumption underpinning Ecological Sites is that soils, topographic, and climatic variables can be correlated with composition and productivity…”
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Potential conservation benefits of a voluntary corporate certification program by Ireland, Alex W., Napoli, Laura J., Basiotis, Katherine A., Voldstad, Emily J., Ostovar, Kayhan

“…Conservation on privately held and working land will be an important component of large-scale efforts aimed at tempering habitat loss to protect biodiversity…”
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Hydroclimatic variability drives episodic expansion of a floating peat mat in a North American kettlehole basin by Ireland, Alex W, Booth, Robert K

“…The coming century is predicted to feature enhanced climatic variability, including increased frequency, intensity, and duration of extreme climatic events…”
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A comparative study of within-basin and regional peatland development: implications for peatland carbon dynamics by Ireland, Alex W., Booth, Robert K., Hotchkiss, Sara C., Schmitz, Jennifer E.

“…Northern peatlands are among the most carbon-rich ecosystems on Earth, but many unanswered questions remain regarding linkages between their long-term…”
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Widespread dust deposition on North American peatlands coincident with European land-clearance by Ireland, Alex W, Clifford, Michael J, Booth, Robert K

“…Ecosystems around the world are being subjected to numerous human disturbances. Climate change and land degradation are the most obvious of these disturbances…”
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Drought as a Trigger for Rapid State Shifts in Kettle Ecosystems: Implications for Ecosystem Responses to Climate Change by Ireland, Alex W., Booth, Robert K., Hotchkiss, Sara C., Schmitz, Jennifer E.

“…Global climate change has raised important questions about ecosystem resilience and the likelihood of unexpected and potentially irreversible ecosystem state…”
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Provisional, Forested Ecological Sites in the Northern Appalachians and Their State-and-Transition Models by Drohan, Patrick J, Ireland, Alex W

“…The identification of unique areas of vegetative potential across the Northern Appalachians is complicated by a long land-use history of vegetation management…”
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Field experiment demonstrates the potential utility of satellite-derived reflectance indices for monitoring regeneration of boreal forest communities by Ireland, Alex W., Smith, François G.F., Jaffe, Benjamin D., Palandro, David A., Mercer, Sean M., Liu, Lei, Renton, Jeff

“…•Reflectance indices derived from high spatial-resolution satellite imagery can be used to inform early-stage reforestation metrics.•Stem density can be…”
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Synthesis and structure–activity relationships of small molecule inhibitors of the simian virus 40 T antigen oncoprotein, an anti-polyomaviral target by Ireland, Alex W., Gobillot, Theodore A., Gupta, Tushar, Seguin, Sandlin P., Liang, Mary, Resnick, Lynn, Goldberg, Margot T., Manos-Turvey, Alexandra, Pipas, James M., Wipf, Peter, Brodsky, Jeffrey L.

“…[Display omitted] Polyomavirus infections are common and relatively benign in the general human population but can become pathogenic in immunosuppressed…”
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High-resolution satellite imagery applied to monitoring revegetation of oil-sands-exploration well pads by Dacre, Cynthia K, Palandro, David A, Oldak, Anna, Ireland, Alex W, Mercer, Sean M

“…To achieve reclamation certification, oil-and-gas operations in Alberta, Canada are required to monitor the revegetation of idle well pads that no longer…”
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A screen for modulators of large T antigen’s ATPase activity uncovers novel inhibitors of Simian Virus 40 and BK virus replication by Seguin, Sandlin P., Ireland, Alex W., Gupta, Tushar, Wright, Christine M., Miyata, Yoshinari, Wipf, Peter, Pipas, James M., Gestwicki, Jason E., Brodsky, Jeffrey L.

“…► Polyomaviruses are linked to an increasing number of diseases. ► To date, specific therapeutics that target this class of viruses are not known. ► A…”
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An integrated reconstruction of recent forest dynamics in a New England cultural landscape by Ireland, Alex W., Oswald, W. Wyatt, Foster, David R.

“…Broad-scale patterns of vegetation response to three centuries of human disturbance in the northeastern United States are well understood, but stand-scale…”
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Bob Marshall's forest reconstruction study: three centuries of ecological resilience to disturbance1 by Ireland, Alex W, Mew, Benjamin J, Foster, David R

“…In 1924, Bob Marshall and his Harvard University advisor Richard Fisher developed an integrated historical approach for forest reconstruction to address…”
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Testing Unmanned Aerial Systems for Monitoring Wildlife at Night by IRELAND, ALEX W., PALANDRO, DAVID A., GARAS, VICTOR Y., WOODS, RICHARD W., DAVI, RICHARD A., BUTLER, JOSH D., GIBBENS, DYAN M., GIBBENS, JEFFREY S

“…Monitoring wildlife populations in proximity to industrial activities, including oil and gas operations, is critical to mitigating potential risk to both…”
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Bob Marshall's Forest Reconstruction Study: Three Centuries of Ecological Resilience to Disturbance by Ireland, Alex W., Mew, Benjamin J., Foster, David R.

“…In 1924, Bob Marshall and his Harvard University advisor Richard Fisher developed an integrated historical approach for forest reconstruction to address…”
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Assessing the sensitivity of kettle ecosystems to climatic and anthropogenic disturbances by Ireland, Alex W

“…Human-induced global change raises important questions about ecosystem resilience to external perturbations. Kettle peatlands have been underutilized in…”
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Assessing the sensitivity of kettle ecosystems to climatic and anthropogenic disturbances by Ireland, Alex W

“…Human-induced global change raises important questions about ecosystem resilience to external perturbations. Kettle peatlands have been underutilized in…”
Get full text