Search Results - "Irelan, Courtney Broshar"

Overlapping function of Hrd1 and Ste24 in translocon quality control provides robust channel surveillance by Runnebohm, Avery M., Richards, Kyle A., Irelan, Courtney Broshar, Turk, Samantha M., Vitali, Halie E., Indovina, Christopher J., Rubenstein, Eric M.

“…Translocation of proteins across biological membranes is essential for life. Proteins that clog the endoplasmic reticulum (ER) translocon prevent the movement…”
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Lipid biosynthesis perturbation impairs endoplasmic reticulum–associated degradation by Turk, Samantha M., Indovina, Christopher J., Miller, Jacob M., Overton, Danielle L., Runnebohm, Avery M., Orchard, Cade J., Tragesser-Tiña, Mary E., Gosser, Samantha K., Doss, Ellen M., Richards, Kyle A., Irelan, Courtney Broshar, Daraghmi, Mahmoud M., Bailey, Connor G., Niekamp, Julia M., Claypool, Kieran P., Engle, Sarah M., Buchanan, Bryce W., Woodruff, Kelsey A., Olesen, James B., Smaldino, Philip J., Rubenstein, Eric M.

“…The relationship between lipid homeostasis and protein homeostasis (proteostasis) is complex and remains incompletely understood. We conducted a screen for…”
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Inner Nuclear Membrane Asi Ubiquitin Ligase Catalytic Subunits Asi1p and Asi3p, but not Asi2p, confer resistance to aminoglycoside hygromycin B in Saccharomyces cerevisiae by Woodruff, Kelsey A, Richards, Kyle A, Evans, Melissa D, Scott, Abigail R, Voas, Brian M, Irelan, Courtney Broshar, Olesen, James B, Smaldino, Philip J, Rubenstein, Eric M

“…The heterotrimeric Asi ubiquitin ligase (encoded by ASI1 , ASI2 , and ASI3 ) mediates protein degradation in the inner nuclear membrane in Saccharomyces…”
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