Search Results - "Ira M. Longini"
-
1
Evolving epidemiology and transmission dynamics of coronavirus disease 2019 outside Hubei province, China: a descriptive and modelling study
Published in The Lancet infectious diseases (01-07-2020)“…The coronavirus disease 2019 (COVID-19) epidemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began in Wuhan city, Hubei province,…”
Get full text
Journal Article -
2
The effect of travel restrictions on the spread of the 2019 novel coronavirus (COVID-19) outbreak
Published in Science (American Association for the Advancement of Science) (24-04-2020)“…Motivated by the rapid spread of coronavirus disease 2019 (COVID-19) in mainland China, we use a global metapopulation disease transmission model to project…”
Get full text
Journal Article -
3
Estimating the impact of COVID-19 vaccine inequities: a modeling study
Published in Nature communications (06-06-2023)“…Access to COVID-19 vaccines on the global scale has been drastically hindered by structural socio-economic disparities. Here, we develop a data-driven,…”
Get full text
Journal Article -
4
Inferring high-resolution human mixing patterns for disease modeling
Published in Nature communications (12-01-2021)“…Mathematical and computational modeling approaches are increasingly used as quantitative tools in the analysis and forecasting of infectious disease epidemics…”
Get full text
Journal Article -
5
Modelling the impact of testing, contact tracing and household quarantine on second waves of COVID-19
Published in Nature human behaviour (01-09-2020)“…While severe social-distancing measures have proven effective in slowing the coronavirus disease 2019 (COVID-19) pandemic, second-wave scenarios are likely to…”
Get full text
Journal Article -
6
Transmissibility and Control of Pandemic Influenza A (H1N1) Virus
Published in Science (American Association for the Advancement of Science) (30-10-2009)“…Pandemic influenza A (H1N1) 2009 (pandemic H1N1) is spreading throughout the planet. It has become the dominant strain in the Southern Hemisphere, where the…”
Get full text
Journal Article -
7
Epidemiological benefits of more-effective tuberculosis vaccines, drugs, and diagnostics
Published in Proceedings of the National Academy of Sciences - PNAS (18-08-2009)“…The Bill and Melinda Gates Foundation supports an ambitious portfolio of novel vaccines, drug regimens, and diagnostic tools for tuberculosis (TB). We elicited…”
Get full text
Journal Article -
8
Considerations in boosting COVID-19 vaccine immune responses
Published in The Lancet (British edition) (09-10-2021)“…A new wave of COVID-19 cases caused by the highly transmissible delta variant is exacerbating the worldwide public health crisis, and has led to consideration…”
Get full text
Journal Article -
9
Modeling targeted layered containment of an influenza pandemic in the United States
Published in Proceedings of the National Academy of Sciences - PNAS (25-03-2008)“…Planning a response to an outbreak of a pandemic strain of influenza is a high public health priority. Three research groups using different individual-based,…”
Get full text
Journal Article -
10
Quantifying the importance and location of SARS-CoV-2 transmission events in large metropolitan areas
Published in Proceedings of the National Academy of Sciences - PNAS (28-06-2022)“…Detailed characterization of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission across different settings can help design less…”
Get full text
Journal Article -
11
Mitigation Strategies for Pandemic Influenza in the United States
Published in Proceedings of the National Academy of Sciences - PNAS (11-04-2006)“…Recent human deaths due to infection by highly pathogenic (H5N1) avian influenza A virus have raised the specter of a devastating pandemic like that of…”
Get full text
Journal Article -
12
Vaccination strategies for epidemic cholera in Haiti with implications for the developing world
Published in Proceedings of the National Academy of Sciences - PNAS (26-04-2011)“…In October 2010, a virulent South Asian strain of El Tor cholera began to spread in Haiti. Interventions have included treatment of cases and improved…”
Get full text
Journal Article -
13
Containing Pandemic Influenza at the Source
Published in Science (American Association for the Advancement of Science) (12-08-2005)“…Highly pathogenic avian influenza A (subtype H5N1) is threatening to cause a human pandemic of potentially devastating proportions. We used a stochastic…”
Get full text
Journal Article -
14
Spatiotemporal spread of the 2014 outbreak of Ebola virus disease in Liberia and the effectiveness of non-pharmaceutical interventions: a computational modelling analysis
Published in The Lancet infectious diseases (01-02-2015)“…Summary Background The 2014 epidemic of Ebola virus disease in parts of west Africa defines an unprecedented health threat. We developed a model of Ebola virus…”
Get full text
Journal Article -
15
FluTE, a publicly available stochastic influenza epidemic simulation model
Published in PLoS computational biology (01-01-2010)“…Mathematical and computer models of epidemics have contributed to our understanding of the spread of infectious disease and the measures needed to contain or…”
Get full text
Journal Article -
16
Household Transmission of SARS-CoV-2: A Systematic Review and Meta-analysis
Published in JAMA network open (01-12-2020)“…Crowded indoor environments, such as households, are high-risk settings for the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…”
Get full text
Journal Article -
17
A systematic review and meta-analysis on the effectiveness of bivalent mRNA booster vaccines against Omicron variants
Published in Vaccine (31-05-2024)“…A global shift to bivalent mRNA vaccines is ongoing to counterbalance the diminishing effectiveness of the original monovalent vaccines due to the evolution of…”
Get full text
Journal Article -
18
Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial
Published in The Lancet (British edition) (29-08-2015)“…Summary Background A recombinant, replication-competent vesicular stomatitis virus-based vaccine expressing a surface glycoprotein of Zaire Ebolavirus…”
Get full text
Journal Article -
19
Hypothesis testing and sample size considerations for the test-negative design
Published in BMC medical research methodology (16-07-2024)“…The test-negative design (TND) is an observational study design to evaluate vaccine effectiveness (VE) that enrolls individuals receiving diagnostic testing…”
Get full text
Journal Article -
20
Transmissibility and Pathogenicity of Ebola Virus: A Systematic Review and Meta-analysis of Household Secondary Attack Rate and Asymptomatic Infection
Published in Clinical infectious diseases (15-05-2016)“…Factors affecting our ability to control an Ebola outbreak include transmissibility of the virus and the proportion of transmissions occurring…”
Get full text
Journal Article