Search Results - "Iqbal, Najeeha T."

Pathobiome driven gut inflammation in Pakistani children with Environmental Enteric Dysfunction by Iqbal, Najeeha T, Syed, Sana, Kabir, Furqan, Jamil, Zehra, Akhund, Tauseef, Qureshi, Shahida, Liu, Jie, Ma, Jennie Z, Guleria, Shan, Gewirtz, Andrew, Duggan, Christopher P, Hughes, Molly A, Sadiq, Kamran, Ali, Asad

“…Environmental Enteric Dysfunction (EED) is an acquired small intestinal inflammatory condition underlying high rates of stunting in children <5 years of age in…”
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Machine learning model demonstrates stunting at birth and systemic inflammatory biomarkers as predictors of subsequent infant growth - a four-year prospective study by Harrison, Elizabeth, Syed, Sana, Ehsan, Lubaina, Iqbal, Najeeha T, Sadiq, Kamran, Umrani, Fayyaz, Ahmed, Sheraz, Rahman, Najeeb, Jakhro, Sadaf, Ma, Jennie Z, Hughes, Molly, Ali, S Asad

“…Stunting affects up to one-third of the children in low-to-middle income countries (LMICs) and has been correlated with decline in cognitive capacity and…”
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Serum anti-flagellin and anti-lipopolysaccharide immunoglobulins as predictors of linear growth faltering in Pakistani infants at risk for environmental enteric dysfunction by Syed, Sana, Iqbal, Najeeha T, Sadiq, Kamran, Ma, Jennie Z, Akhund, Tauseef, Xin, Wenjun, Moore, Sean R, Liu, Enju, Qureshi, Shahida, Gosselin, Kerri, Gewirtz, Andrew, Duggan, Christopher P, Ali, S Asad

“…Environmental Enteric Dysfunction (EED) in children from low-income countries has been linked to linear growth declines. There is a critical need to identify…”
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Study of Environmental Enteropathy and Malnutrition (SEEM) in Pakistan: protocols for biopsy based biomarker discovery and validation by Iqbal, Najeeha T, Syed, Sana, Sadiq, Kamran, Khan, Marium N, Iqbal, Junaid, Ma, Jennie Z, Umrani, Fayaz, Ahmed, Sheraz, Maier, Elizabeth A, Denson, Lee A, Haberman, Yael, McNeal, Monica M, Setchell, Kenneth D R, Zhao, Xueheng, Qureshi, Shahida, Shen, Lanlan, Moskaluk, Christopher A, Liu, Ta-Chiang, Yilmaz, Omer, Brown, Donald E, Barratt, Michael J, Kung, Vanderlene L, Gordon, Jeffrey I, Moore, Sean R, Ali, S Asad

“…Environmental Enteropathy (EE), characterized by alterations in intestinal structure, function, and immune activation, is believed to be an important…”
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High SMAD7 and p-SMAD2,3 expression is associated with environmental enteropathy in children by Syed, Sana, Dinallo, Vincenzo, Iqbal, Najeeha T, Di Iorio, Laura, Di Fusco, Davide, Guleria, Shan, Amadi, Beatrice C, Sadiq, Kamran, Moskaluk, Christopher, Ali, S Asad, Kelly, Paul, Monteleone, Giovanni

“…Enteropathies such as Crohn's disease are associated with enteric inflammation characterized by impaired TGF-β signaling, decreased expression of…”
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Co-carriage of Staphylococcus aureus and Streptococcus pneumoniae among children younger than 2 years of age in a rural population in Pakistan by Shahid, Shahira, Nisar, Muhammad Imran, Jehan, Fyezah, Ahmed, Sheraz, Kabir, Furqan, Hotwani, Aneeta, Muneer, Sahrish, Qazi, Muhammad Farrukh, Muhammad, Sajid, Ali, Asad, Zaidi, Anita K.M., Iqbal, Najeeha T.

“…Staphylococcus aureus and Streptococcus pneumoniae are common colonizers of the human nasopharynx. In this study, we describe S. aureus nasopharyngeal carriage…”
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Assessment of Machine Learning Detection of Environmental Enteropathy and Celiac Disease in Children by Syed, Sana, Al-Boni, Mohammad, Khan, Marium N, Sadiq, Kamran, Iqbal, Najeeha T, Moskaluk, Christopher A, Kelly, Paul, Amadi, Beatrice, Ali, S Asad, Moore, Sean R, Brown, Donald E

“…Duodenal biopsies from children with enteropathies associated with undernutrition, such as environmental enteropathy (EE) and celiac disease (CD), display…”
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A shared group of bacterial taxa in the duodenal microbiota of undernourished Pakistani children with environmental enteric dysfunction by Iqbal, Najeeha T, Chen, Robert Y, Griffin, Nicholas W, Hibberd, Matthew C, Khalid, Aqsa, Sadiq, Kamran, Jamil, Zehra, Ahmed, Kumail, Iqbal, Junaid, Hotwani, Aneeta, Kabir, Furqan, Rahman, Najeeb, Rizvi, Arjumand, Idress, Romana, Ahmed, Zubair, Ahmed, Sheraz, Umrani, Fayaz, Syed, Sana, Moore, Sean R, Ali, Asad, Barratt, Michael J, Gordon, Jeffrey I

“…Environmental enteric dysfunction (EED) is a subclinical syndrome of altered small intestinal function postulated to be an important contributor to childhood…”
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Machine-learning-based integrative –‘omics analyses reveal immunologic and metabolic dysregulation in environmental enteric dysfunction by Zulqarnain, Fatima, Zhao, Xueheng, Setchell, Kenneth D.R., Sharma, Yash, Fernandes, Phillip, Srivastava, Sanjana, Shrivastava, Aman, Ehsan, Lubaina, Jain, Varun, Raghavan, Shyam, Moskaluk, Christopher, Haberman, Yael, Denson, Lee A., Mehta, Khyati, Iqbal, Najeeha T., Rahman, Najeeb, Sadiq, Kamran, Ahmad, Zubair, Idress, Romana, Iqbal, Junaid, Ahmed, Sheraz, Hotwani, Aneeta, Umrani, Fayyaz, Amadi, Beatrice, Kelly, Paul, Brown, Donald E., Moore, Sean R., Ali, Syed Asad, Syed, Sana

“…Environmental enteric dysfunction (EED) is a subclinical enteropathy challenging to diagnose due to an overlap of tissue features with other inflammatory…”
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Mucosal Genomics Implicate Lymphocyte Activation and Lipid Metabolism in Refractory Environmental Enteric Dysfunction by Haberman, Yael, Iqbal, Najeeha T., Ghandikota, Sudhir, Mallawaarachchi, Indika, Tzipi Braun, Dexheimer, Phillip J., Rahman, Najeeb, Hadar, Rotem, Sadiq, Kamran, Ahmad, Zubair, Idress, Romana, Iqbal, Junaid, Ahmed, Sheraz, Hotwani, Aneeta, Umrani, Fayyaz, Ehsan, Lubaina, Medlock, Greg, Syed, Sana, Moskaluk, Chris, Ma, Jennie Z., Jegga, Anil G., Moore, Sean R., Ali, Syed Asad, Denson, Lee A.

“…Environmental enteric dysfunction (EED) limits the Sustainable Development Goals of improved childhood growth and survival. We applied mucosal genomics to…”
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Vitamin D status and risk of incident tuberculosis disease: A nested case-control study, systematic review, and individual-participant data meta-analysis by Aibana, Omowunmi, Huang, Chuan-Chin, Aboud, Said, Arnedo-Pena, Alberto, Becerra, Mercedes C, Bellido-Blasco, Juan Bautista, Bhosale, Ramesh, Calderon, Roger, Chiang, Silvia, Contreras, Carmen, Davaasambuu, Ganmaa, Fawzi, Wafaie W, Franke, Molly F, Galea, Jerome T, Garcia-Ferrer, Daniel, Gil-Fortuño, Maria, Gomila-Sard, Barbará, Gupta, Amita, Gupte, Nikhil, Hussain, Rabia, Iborra-Millet, Jesus, Iqbal, Najeeha T, Juan-Cerdán, Jose Vicente, Kinikar, Aarti, Lecca, Leonid, Mave, Vidya, Meseguer-Ferrer, Noemi, Montepiedra, Grace, Mugusi, Ferdinand M, Owolabi, Olumuyiwa A, Parsonnet, Julie, Roach-Poblete, Freddy, Romeu-García, Maria Angeles, Spector, Stephen A, Sudfeld, Christopher R, Tenforde, Mark W, Togun, Toyin O, Yataco, Rosa, Zhang, Zibiao, Murray, Megan B

“…Few studies have evaluated the association between preexisting vitamin D deficiency and incident tuberculosis (TB). We assessed the impact of baseline vitamins…”
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Environmental enteropathy by Ali, Asad, Iqbal, Najeeha T, Sadiq, Kamran

“…PURPOSE OF REVIEWEnvironmental enteropathy has long been recognized as an important intermediary condition leading to chronic malnutrition in children in…”
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Duration of Postdiarrheal Enteric Pathogen Carriage in Young Children in Low-resource Settings by McMurry, Timothy L, McQuade, Elizabeth T Rogawski, Liu, Jie, Kang, Gagandeep, Kosek, Margaret N, Lima, Aldo A M, Bessong, Pascal O, Samie, Amidou, Haque, Rashidul, Mduma, Estomih R, Leite, Jose Paulo, Bodhidatta, Ladaporn, Iqbal, Najeeha T, Page, Nicola, Kiwelu, Ireen, Bhutta, Zulfiqar A, Ahmed, Tahmeed, Houpt, Eric R, Platts-Mills, James A

“…Abstract Background Prolonged enteropathogen shedding after diarrhea complicates the identification of etiology in subsequent episodes and is an important…”
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Bile Acid Profiling Reveals Distinct Signatures in Undernourished Children with Environmental Enteric Dysfunction by Zhao, Xueheng, Setchell, Kenneth D R, Huang, Rong, Mallawaarachchi, Indika, Ehsan, Lubaina, Dobrzykowski Iii, Edward, Zhao, Junfang, Syed, Sana, Ma, Jennie Z, Iqbal, Najeeha T, Iqbal, Junaid, Sadiq, Kamran, Ahmed, Sheraz, Haberman, Yael, Denson, Lee A, Ali, Syed Asad, Moore, Sean R

“…Intestinal inflammation and malabsorption in environmental enteric dysfunction (EED) are associated with early childhood growth faltering in impoverished…”
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Differential coverage for vaccines in the expanded program on immunization (EPI) among children in rural Pakistan by Shahid, Shahira, Ahmed, Sheraz, Qazi, Muhammad Farrukh, Ali, Rafey, Ali, Syed Asad, Zaidi, Anita K.M., Iqbal, Najeeha T., Jehan, Fyezah, Imran Nisar, Muhammad

“…•Vaccine coverage and timeliness were low among children in Matiari, Pakistan.•48.4 % of the children were fully vaccinated with all EPI antigens.•Majority of…”
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Enteric pathogens relationship with small bowel histologic features of environmental enteric dysfunction in a multicountry cohort study by Iqbal, Najeeha T, Lawrence, Sarah, Ahmed, Tahmeed, Chandwe, Kanta, Fahim, Shah M, Houpt, Eric R, Kabir, Furqan, Kelly, Paul, Liu, Jie, Mahfuz, Mustafa, Mweetwa, Monica, VanBuskirk, Kelley, Tarr, Phillip I, Denno, Donna M, Ahmed, Kumail, Ahmed, Sheraz, Alam, Md. Ashraful, Ali, S. Asad, Amadi, Beatrice, Das, Subhasish, Gazi, Md. Amran, Haque, Rashidul, Hasan, Md. Mehedi, Hossain, Md. Shabab, Hotwani, Aneeta, Hussain, Shahneel, Iqbal, Junaid, Jakhro, Sadaf, Liu, Ta-Chiang, Mazumder, Ramendra Nath, Moskaluk, Christopher A, Qureshi, Abdul Khalique, Raghavan, Shyam S, Rahman, Masudur, Rahman, Najeeb, Sadiq, Kamran, Sarker, Shafiqul Alam, Sullivan, Peter B, Tearney, Guillermo J, Umrani, Fayaz, Yilmaz, Omer H, Zyambo, Kanekwa

“…Environmental Enteric Dysfunction (EED) is an acquired disorder of asymptomatic altered gut function, the etiology of which is unknown. EED is postulated to be…”
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Biomarker relationships with small bowel histopathology among malnourished children with environmental enteric dysfunction in a multicountry cohort study by Mahfuz, Mustafa, Coomes, David, Abdalla, Marwa, Mweetwa, Monica, VanBuskirk, Kelley, Iqbal, Najeeha T, Ali, S Asad, Chandwe, Kanta, Das, Subhasish, Kelly, Paul, Shaikh, Nurmohammad, Tarr, Phillip I, Denno, Donna M, Ahmed, Kumail, Ahmed, Sheraz, Ahmed, Tahmeed, Alam, Md. Ashraful, Amadi, Beatrice, Begum, S.M. Khodeza Nahar, Besa, Ellen, Fahim, Shah Mohammad, Gazi, Md. Amran, Gilchrist, Carol A., Haque, Rashidul, Hasan, Md. Mehedi, Hossain, Md. Shabab, Hotwani, Aneeta, Hussain, Shahneel, Iqbal, Junaid, Jakhro, Sadaf, Kabir, Furqan, Liu, Ta-Chiang, Mann, Barbara J., Mazumder, Ramendra Nath, Memon, Waheeda, Moskaluk, Christopher A, Qureshi, Abdul Khalique, Ragahavan, Shyam S, Rahman, Masudur, Rahman, Najeeb, Sadiq, Kamran, Sarker, Shafiqul Alam, Sullivan, Peter B, Tearney, Guillermo J., Umrani, Fayaz, Yilmaz, Omer H., Zyambo, Kanekwa

“…Validated biomarkers could catalyze environmental enteric dysfunction (EED) research. Leveraging an EED histology scoring system, this multicountry analysis…”
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Artificial Intelligence‐based Analytics for Diagnosis of Small Bowel Enteropathies and Black Box Feature Detection by Syed, Sana, Ehsan, Lubaina, Shrivastava, Aman, Sengupta, Saurav, Khan, Marium, Kowsari, Kamran, Guleria, Shan, Sali, Rasoul, Kant, Karan, Kang, Sung‐Jun, Sadiq, Kamran, Iqbal, Najeeha T., Cheng, Lin, Moskaluk, Christopher A., Kelly, Paul, Amadi, Beatrice C., Asad Ali, Syed, Moore, Sean R., Brown, Donald E.

“…ABSTRACT Objectives: Striking histopathological overlap between distinct but related conditions poses a disease diagnostic challenge. There is a major clinical…”
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Distance from Healthcare Facilities Is Associated with Increased Morbidity of Acute Infection in Pediatric Patients in Matiari, Pakistan by Corden, Elise, Siddiqui, Saman Hasan, Sharma, Yash, Raghib, Muhammad Faraz, Adorno, 3rd, William, Zulqarnain, Fatima, Ehsan, Lubaina, Shrivastava, Aman, Ahmed, Sheraz, Umrani, Fayaz, Rahman, Najeeb, Ali, Rafey, Iqbal, Najeeha T, Moore, Sean R, Ali, Syed Asad, Syed, Sana

“…The relationship between environmental factors and child health is not well understood in rural Pakistan. This study characterized the environmental factors…”
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Impact of diarrhoea and acute respiratory infection on environmental enteric dysfunction and growth of malnourished children in Pakistan: a longitudinal cohort study by Sarfraz, Azza, Jamil, Zehra, Ahmed, Sheraz, Umrani, Fayaz, Qureshi, Abdul Khaliq, Jakhro, Sadaf, Sajid, Muhammad, Rahman, Najeeb, Rizvi, Arjumand, Ma, Jennie Z., Mallawaarachchi, Indika, Iqbal, Najeeha T., Syed, Sana, Iqbal, Junaid, Sadiq, Kamran, Moore, Sean R., Ali, Syed Asad

“…Diarrhoea and acute respiratory infections (ARI) are assumed to be major drivers of growth and likely contribute to environmental enteric dysfunction (EED),…”
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