Search Results - "Iqbal, Kiran"

IgG antibodies to SARS-CoV-2 in asymptomatic blood donors at two time points in Karachi by Hasan, Muhammad, Moiz, Bushra, Qaiser, Shama, Masood, Kiran Iqbal, Ghous, Zara, Hussain, Areeba, Ali, Natasha, Simas, J. Pedro, Veldhoen, Marc, Alves, Paula, Abidi, Syed Hani, Ghias, Kulsoom, Khan, Erum, Hasan, Zahra

“…Introduction An estimated 1.5 million cases were reported in Pakistan until 23 March, 2022. However, SARS-CoV-2 PCR testing capacity has been limited and the…”
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Upregulated type I interferon responses in asymptomatic COVID-19 infection are associated with improved clinical outcome by Masood, Kiran Iqbal, Yameen, Maliha, Ashraf, Javeria, Shahid, Saba, Mahmood, Syed Faisal, Nasir, Asghar, Nasir, Nosheen, Jamil, Bushra, Ghanchi, Najia Karim, Khanum, Iffat, Razzak, Safina Abdul, Kanji, Akbar, Hussain, Rabia, E. Rottenberg, Martin, Hasan, Zahra

“…Understanding key host protective mechanisms against SARS-CoV-2 infection can help improve treatment modalities for COVID-19. We used a blood transcriptome…”
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Higher entropy observed in SARS-CoV-2 genomes from the first COVID-19 wave in Pakistan by Ghanchi, Najia Karim, Nasir, Asghar, Masood, Kiran Iqbal, Abidi, Syed Hani, Mahmood, Syed Faisal, Kanji, Akbar, Razzak, Safina, Khan, Waqasuddin, Shahid, Saba, Yameen, Maliha, Raza, Ali, Ashraf, Javaria, Ansar, Zeeshan, Dharejo, Mohammad Buksh, Islam, Nazneen, Hasan, Zahra, Hasan, Rumina

“…Background We investigated the genome diversity of SARS-CoV-2 associated with the early COVID-19 period to investigate evolution of the virus in Pakistan…”
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SARS-CoV-2 variants induce increased inflammatory gene expression but reduced interferon responses and heme synthesis as compared with wild type strains by Merchant, Mariam, Ashraf, Javaria, Masood, Kiran Iqbal, Yameen, Maliha, Hussain, Rabia, Nasir, Asghar, Hasan, Zahra

“…SARS-CoV-2 variants of concern (VOC) have been associated with increased viral transmission and disease severity. We investigated the mechanisms of…”
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A rapid real-time polymerase chain reaction-based live virus microneutralization assay for detection of neutralizing antibodies against SARS-CoV-2 in blood/serum by Abidi, Syed Hani, Imtiaz, Kehkashan, Kanji, Akbar, Qaiser, Shama, Khan, Erum, Iqbal, Kiran, Veldhoen, Marc, Ghias, Kulsoom, Simas, J Pedro, Hasan, Zahra

“…Copyright: © 2021 Abidi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits…”
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Disparities in age and gender-specific SARS-CoV-2 diagnostic testing trends: a retrospective study from Pakistan by Ghanchi, Najia Karim, Masood, Kiran Iqbal, Qazi, Muhammad Farrukh, Shahid, Shahira, Nasir, Asghar, Mahmood, Syed Faisal, Ansar, Zeeshan, Nisar, Muhammad Imran, Hasan, Zahra

“…Pakistan reported 1.57 million COVID-19 cases between 2020 and 2022, based on approximately 30.6 million SARS-CoV-2 RT-PCR (reverse-transcription polymerase…”
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Diagnostic accuracy of different cut-off values of adenosine deaminase levels in tuberculous pleural effusion by Masood, Kiran Iqbal, Shahid, Shayan, Jabeen, Kauser, Farooqi, Joveria, Kerawala, Sabeika Raza, Irfan, Muhammad

“…To assess the diagnostic accuracy of different cut-off values of pleural fluid adenosine deaminase levels as a diagnostic method for tuberculous pleural…”
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Latent M. tuberculosis infection is associated with increased inflammatory cytokine and decreased suppressor of cytokine signalling (SOCS)‐3 in the diabetic host by Masood, Kiran Iqbal, Irfan, Muhammad, Masood, Qamar, Yameen, Maliha, Jamil, Bushra, Ram, Nanik, Rao, Shoaib, Rottenberg, Martin, Hasan, Zahra

“…Tuberculosis (TB) outcomes are worsened by type II diabetes mellitus (DM). Protective immunity against Mycobacterium tuberculosis (MTB) is driven by cytokines…”
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Lipid A-Ara4N as an alternate pathway for (colistin) resistance in Klebsiella pneumonia isolates in Pakistan by Masood, Kiran Iqbal, Umar, Seema, Hasan, Zahra, Farooqi, Joveria, Razzak, Safina Abdul, Jabeen, Nazish, Rao, Jason, Shakoor, Sadia, Hasan, Rumina

“…This study aimed to explore mechanism of colistin resistance amongst Klebsiella pneumoniae isolates through plasmid mediated mcr-1 gene in Pakistan. Carbapenem…”
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Tuberculosis and diabetes mellitus: Relating immune impact of co-morbidity with challenges in disease management in high burden countries by Abbas, Uzair, Masood, Kiran Iqbal, Khan, Aalia, Irfan, Muhammad, Saifullah, Nausheen, Jamil, Bushra, Hasan, Zahra

“…Mycobacterium tuberculosis (MTB) is the causative agent of TB. TB incidence is high in many low resource settings where limited health systems make it…”
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Role of TNF α, IL-6 and CXCL10 in Dengue disease severity by Masood, Kiran Iqbal, Jamil, Bushra, Rahim, Maryam, Islam, Muniba, Farhan, Muhammad, Hasan, Zahra

“…Dengue virus infections (Dengue) have become increasingly common in Pakistan and can result in case fatalities if not managed appropriately. Patients with…”
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Humoral and T cell responses to SARS-CoV-2 reveal insights into immunity during the early pandemic period in Pakistan by Masood, Kiran Iqbal, Qaiser, Shama, Abidi, Syed Hani, Khan, Erum, Mahmood, Syed Faisal, Hussain, Areeba, Ghous, Zara, Imtiaz, Khekahsan, Ali, Natasha, Hasan, Muhammad, Memon, Haris Ali, Yameen, Maliha, Ali, Shiza, Baloch, Sadaf, Lakhani, Gulzar, Alves, Paula M, Iqbal, Najeeha Talat, Ahmed, Kumail, Iqbal, Junaid, Bhutta, Zulfiqar A, Hussain, Rabia, Rottenberg, Martin, Simas, J. Pedro, Veldhoen, Marc, Ghias, Kulsoom, Hasan, Zahra

“…Abstract Background Protection against SARS-CoV-2 is mediated by humoral and T cell responses. Pakistan faced relatively low morbidity and mortality from…”
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Immune mapping of human tuberculosis and sarcoidosis lung granulomas by Carow, Berit, Muliadi, Victoria, Skålén, Kristina, Yokota, Chika, Kathamuthu, Gokul Raj, Setiabudiawan, Todia Pediatama, Lange, Christoph, Scheu, Katrin, Gaede, Karoline I, Goldmann, Torsten, Pandita, Ankur, Masood, Kiran Iqbal, Pervez, Shahid, Grunewald, Johan, Hasan, Zahra, Levin, Max, Rottenberg, Martin E

“…Tuberculosis (TB) and sarcoidosis are both granulomatous diseases. Here, we compared the immunological microenvironments of granulomas from TB and sarcoidosis…”
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Therapeutic role of vitamin D in COVID-19 patients by Imran, Muhammad, Zia, Ramna, Ali, Maryam, Sadaf, Saima, Iqbal, Kiran, Ali, Asad, Iqbal, Usama, Din, Sana Muhammad, Shahid, Jawaria, Ahsan, Ali, Kalim, Zahra, Shabbir, Chaudhry Ahmed, Ullah, Sajjad

“…SARS-CoV-2 has had a significant worldwide impact, leading to widespread illness and mortality. With the lack of specific antiviral treatments, there is a…”
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Effects of physiotherapy in the management of cancer-related pain and fatigue: A systematic review of randomized controlled trials by Ameer Shaikh, Hajra, Anjum, Okasha, Iqbal, Kiran, Zaidi, Syeda Wajeeha Raza

“…Background: Cancer is ranked as the 2nd common deadliest disorder worldwide, and the growing incidence demands updating and optimizing the treatment strategies…”
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Investigating the impact of prior COVID-19 on IgG antibody and interferon γ responses after BBIBP-CorV vaccination in a disease endemic population: A prospective observational study by Hasan, Zahra, Masood, Kiran Iqbal, Qaiser, Shama, Khan, Erum, Hussain, Areeba, Ghous, Zara, Khan, Unab, Yameen, Maliha, Hassan, Imran, Nasir, Muhammad Imran, Qazi, Muhammad Farrukh, Memon, Haris Ali, Ali, Shiza, Baloch, Sadaf, Bhutta, Zulfiqar A, Veldhoen, Marc, Pedro Simas, J, Mahmood, Syed Faisal, Ghias, Kulsoom, Hussain, Rabia

“…COVID-19 vaccinations have reduced morbidity and mortality from the disease. Antibodies against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2)…”
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Testing for Mycobacterium tuberculosis infection using the QuantiFERON-TB GOLD assay in patients with comorbid conditions in a tertiary care endemic setting by Masood, Kiran Iqbal, Jamil, Bushra, Akber, Alnoor, Hassan, Maheen, Islam, Muniba, Hasan, Zahra

“…There were 10 million new cases of tuberculosis (TB) in 2017. To eliminate TB, it is necessary to diagnose active TB and latent tuberculosis infection (LTBI)…”
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Tracking SARS-CoV-2 variants through pandemic waves using RT-PCR testing in low-resource settings by Nasir, Asghar, Aamir, Uzma Bashir, Kanji, Akbar, Bukhari, Ali Raza, Ansar, Zeeshan, Ghanchi, Najia Karim, Masood, Kiran Iqbal, Samreen, Azra, Islam, Nazneen, Ghani, Samina, Syed, M Asif, Wassan, Mansoor, Mahmood, Syed Faisal, Hasan, Zahra

“…COVID-19 resulted in extensive morbidity and mortality worldwide. SARS-CoV-2 evolved rapidly, with increasing transmission due to Variants of Concern (VOC)…”
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Increased Expression of Efflux Pump Genes in Extensively Drug-Resistant Isolates of Mycobacterium tuberculosis by Kanji, Akbar, Hasan, Rumina, Zhang, Ying, Shi, Wanliang, Imtiaz, Kehkashan, Iqbal, Kiran, Shafiq, Samreen, Hasan, Zahra

“…Abstract Introduction Extensively drug-resistant tuberculosis (XDR-TB) is defined as tuberculosis (TB) caused by Mycobacterium tuberculosis (MTB) strains that…”
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Differential Early Secreted Antigen Target (ESAT) 6 kDa-induced IFN-γ and SOCS1 expression distinguishes latent and active tuberculosis by Masood, Kiran Iqbal, Hussain, Rabia, Rao, Nisar, Rottenberg, Martin E, Salahuddin, Naseem, Irfan, Muhammad, Hasan, Zahra

“…Expression of Suppressor of cytokine signaling (SOCS)-1 molecules is increased in patients with tuberculosis (TB). Early Secreted Antigen Target (ESAT)-6 kDa -…”
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