Search Results - "Ippolito, Chiara"
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Histochemical Detection of Collagen Fibers by Sirius Red/Fast Green Is More Sensitive than van Gieson or Sirius Red Alone in Normal and Inflamed Rat Colon
Published in PloS one (16-12-2015)“…Collagen detection in histological sections and its quantitative estimation by computer-aided image analysis represent important procedures to assess tissue…”
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2
Different Impact of Essential Hypertension on Structural and Functional Age-Related Vascular Changes
Published in Hypertension (Dallas, Tex. 1979) (01-01-2017)“…We evaluated whether vascular remodeling is present in physiological aging and whether hypertension accelerates the aging process for vascular function and…”
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3
Pathological remodelling of colonic wall following dopaminergic nigrostriatal neurodegeneration
Published in Neurobiology of disease (01-06-2020)“…Patients with Parkinson's disease (PD) are often characterized by functional gastrointestinal disorders. Such disturbances can occur at all stages of PD and…”
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4
The flavonoid compound apigenin prevents colonic inflammation and motor dysfunctions associated with high fat diet-induced obesity
Published in PloS one (11-04-2018)“…Apigenin can exert beneficial actions in the prevention of obesity. However, its putative action on obesity-associated bowel motor dysfunctions is unknown…”
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Aging Modulates the Influence of Arginase on Endothelial Dysfunction in Obesity
Published in Arteriosclerosis, thrombosis, and vascular biology (01-10-2018)“…OBJECTIVE—Arginase can reduce NO availability. In this study, we explored arginase as a determinant of endothelial dysfunction in small arteries from obese…”
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Microtubule-associated protein 1B is implicated in stem cell commitment and nervous system regeneration in planarians
Published in PloS one (12-12-2022)“…Microtubule-associated 1B (MAP1B) proteins are expressed at the nervous system level where they control cytoskeleton activity and regulate neurotransmitter…”
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miR-182-5p is an evolutionarily conserved Tbx5 effector that impacts cardiac development and electrical activity in zebrafish
Published in Cellular and molecular life sciences : CMLS (01-08-2020)“…To dissect the TBX5 regulatory circuit, we focused on microRNAs (miRNAs) that collectively contribute to make TBX5 a pivotal cardiac regulator. We profiled…”
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Effect of Combined Levothyroxine (L-T4) and 3-Iodothyronamine (T1AM) Supplementation on Memory and Adult Hippocampal Neurogenesis in a Mouse Model of Hypothyroidism
Published in International journal of molecular sciences (08-09-2023)“…Mood alterations, anxiety, and cognitive impairments associated with adult-onset hypothyroidism often persist despite replacement treatment. In rodent models…”
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Cell quiescence in planarian stem cells, interplay between p53 and nutritional stimuli
Published in Open biology (01-12-2022)“…Cell quiescence appeared early in evolution as an adaptive response to adverse conditions (i.e. nutrient depletion). In metazoans, quiescence has been involved…”
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Ghrelin restores nitric oxide availability in resistance circulation of essential hypertensive patients: role of NAD(P)H oxidase
Published in European heart journal (14-11-2015)“…We assessed whether acute intra-arterial infusion of exogenous ghrelin can improve endothelial dysfunction by restoring nitric oxide (NO) availability in the…”
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Connexin Expression in Human Minor Salivary Glands: An Immunohistochemical Microscopy Study
Published in Molecules (Basel, Switzerland) (01-09-2022)“…Connexins (Cxs) are transmembrane proteins involved in the formation of hemichannels and gap junctions (GJs). GJs are involved in various physiological…”
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Sub-Lethal 5-Fluorouracil Dose Challenges Planarian Stem Cells Promoting Transcriptional Profile Changes in the Pluripotent Sigma-Class Neoblasts
Published in Biomolecules (Basel, Switzerland) (26-06-2021)“…Under physiological conditions, the complex planarian neoblast system is a composite of hierarchically organized stem cell sub-populations with sigma-class…”
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Prodromal Intestinal Events in Alzheimer's Disease (AD): Colonic Dysmotility and Inflammation Are Associated with Enteric AD-Related Protein Deposition
Published in International journal of molecular sciences (15-05-2020)“…Increasing evidence suggests that intestinal dysfunctions may represent early events in Alzheimer's disease and contribute to brain pathology. This study…”
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From the intestinal mucosal barrier to the enteric neuromuscular compartment: an integrated overview on the morphological changes in Parkinson's disease
Published in European journal of histochemistry (22-11-2021)“…Gastrointestinal dysfunctions represent the most common non-motor symptoms in Parkinson's disease (PD). Of note, changes in gut microbiota, impairments of…”
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Immunohistochemical analysis of myenteric ganglia and interstitial cells of Cajal in ulcerative colitis
Published in Journal of cellular and molecular medicine (01-02-2012)“…Ulcerative colitis (UC) is an inflammatory bowel disease with alterations of colonic motility, which influence clinical symptoms. Although morpho‐functional…”
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Deepening the Mechanisms of Visceral Pain Persistence: An Evaluation of the Gut-Spinal Cord Relationship
Published in Cells (Basel, Switzerland) (24-07-2020)“…The management of visceral pain is a major clinical problem in patients affected by gastrointestinal disorders. The poor knowledge about pain chronicization…”
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Inducible modulation of miR-204 levels in a zebrafish melanoma model
Published in Biology open (06-11-2020)“…Here, we present miniCoopR-I, an inducible upgrade of the constitutive miniCoopR vector. We developed miniCoopR-I-sponge-204 and miniCoopR-I-pre-miR-204…”
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Altered expression pattern of molecular factors involved in colonic smooth muscle functions: an immunohistochemical study in patients with diverticular disease
Published in PloS one (20-02-2013)“…The pathogenesis of diverticular disease (DD) is thought to result from complex interactions among dietary habits, genetic factors and coexistence of other…”
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Vascular dysfunction in a mouse model of Rett syndrome and effects of curcumin treatment
Published in PloS one (21-05-2013)“…Mutations in the coding sequence of the X-linked gene MeCP2 (Methyl CpG-binding protein) are present in around 80% of patients with Rett Syndrome, a common…”
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Dysregulated insulin secretion is associated with pancreatic β‐cell hyperplasia and direct acinar‐β‐cell trans‐differentiation in partially eNOS‐deficient mice
Published in Physiological reports (01-08-2022)“…eNOS‐deficient mice were previously shown to develop hypertension and metabolic alterations associated with insulin resistance either in standard dietary…”
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