Search Results - "Ippei Watanabe"

Biochemical and crystallographic assessments of the effect of 4,6‐O‐disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity by Watanabe, Ippei, Miyanaga, Akimasa, Hoshi, Hirotaka, Suzuki, Kiyoshi, Eguchi, Tadashi

“…O‐sulfated N‐acetyl‐d‐galactosamine (GalNAc) residues in chondroitin sulfate (CS) play a crucial role in chondroitinase ABC I (cABC‐I) activity. CSA containing…”
Get full text

Rheological and Adhesive Properties to Identify Cohesive and Dispersive Ophthalmic Viscosurgical Devices by Watanabe, Ippei, Hoshi, Hirotaka, Sato, Miwako, Suzuki, Kiyoshi

“…The purpose of this study is to evaluate the usefulness of the rheological properties and adhesive force of ophthalmic viscosurgical devices (OVDs) as…”
Get full text

Contemporary Management of Stable Coronary Artery Disease　― Implications of the ISCHEMIA Trial by Kohsaka, Shun, Fukushima, Kenji, Watanabe, Ippei, Manabe, Susumu, Niimi, Nozomi, Gatate, Yodo, Sawano, Mitsuaki, Nakano, Shintaro

“…Coronary artery disease (CAD) remains a leading cause of mortality and morbidity in developed countries. Although urgent revascularization is the cornerstone…”
Get full text

Advances in Understanding the Mechanism of Ophthalmic Viscosurgical Device Retention in the Anterior Chamber or on the Corneal Surface during Ocular Surgery by Watanabe, Ippei, Yoshioka, Keiji, Takahashi, Katsuya, Hoshi, Hirotaka, Nagata, Mayumi, Matsushima, Hiroyuki, Suzuki, Kiyoshi

“…Retention durability, especially in the eye, is one of the most important properties of ophthalmic viscosurgical devices (OVDs) during ocular surgery. However,…”
Get full text

KLF2 regulates neutrophil activation and thrombosis in cardiac hypertrophy and heart failure progression by Tang, Xinmiao, Wang, Peiwei, Zhang, Rongli, Watanabe, Ippei, Chang, Eugene, Vinayachandran, Vinesh, Nayak, Lalitha, Lapping, Stephanie, Liao, Sarah, Madera, Annmarie, Sweet, David R, Luo, Jiemeng, Fei, Jinsong, Jeong, Hyun-Woo, Adams, Ralf H, Zhang, Teng, Liao, Xudong, Jain, Mukesh K

“…It is widely recognized that inflammation plays a critical role in cardiac hypertrophy and heart failure. However, clinical trials targeting cytokines have…”
Get full text

Injectable in situ cross-linking hyaluronan hydrogel for easier removal of posterior vitreous cortex in vitrectomy by Hisatomi, Toshio, Tachibana, Takashi, Mori, Kenichiro, Ishikawa, Keijiro, Ishibashi, Tatsuro, Sonoda, Koh-Hei, Uchio, Eiichi, Watanabe, Ippei, Suzuki, Kiyoshi, Iida, Masami

“…Purpose Removing transparent vitreous tissues, such as a residual vitreous cortex (VC) or proliferative membrane, without damaging the retina is often…”
Get full text

Histological analysis of nucleus pulposus tissue from patients with lumbar disc herniation after condoliase administration by Minamisawa, Yuka, Shirogane, Taiichi, Watanabe, Ippei, Dezawa, Akira

“…Background Condoliase is an enzyme used as a treatment for lumbar disc herniation (LDH). This enzyme degrades chondroitin sulfate (CS) in the nucleus pulposus…”
Get full text

Development of in situ crosslinked hyaluronan as an adjunct to vitrectomy surgery by Suzuki, Kiyoshi, Watanabe, Ippei, Tachibana, Takashi, Mori, Kenichiro, Ishikawa, Keijiro, Ishibashi, Tatsuro, Uchio, Eiichi, Sonoda, Koh-Hei, Hisatomi, Toshio

“…Ophthalmologists have used hyaluronan (HA) products as adjuncts to ocular surgery since the 1970s. However, HA products are not always functional in surgeries…”
Get full text

JCS 2022 Guideline Focused Update on Diagnosis and Treatment in Patients With Stable Coronary Artery Disease by Nakano, Shintaro, Kohsaka, Shun, Chikamori, Taishiro, Fukushima, Kenji, Kobayashi, Yoshio, Kozuma, Ken, Manabe, Susumu, Matsuo, Hitoshi, Nakamura, Masato, Ohno, Takayuki, Sawano, Mitsuaki, Toda, Koichi, Ueda, Yasunori, Yokoi, Hiroyoshi, Gatate, Yodo, Kasai, Tokuo, Kawase, Yoshiaki, Matsumoto, Naoya, Mori, Hitoshi, Nakazato, Ryo, Niimi, Nozomi, Saito, Yuichi, Shintani, Ayumi, Watanabe, Ippei, Watanabe, Yusuke, Ikari, Yuji, Jinzaki, Masahiro, Kosuge, Masami, Nakajima, Kenichi, Kimura, Takeshi, on behalf of the JCS Joint Working Group

Get full text

Heart Rate After Resuscitation From Out-of-Hospital Cardiac Arrest due to Acute Coronary Syndrome Is an Independent Predictor of Clinical Outcome by Matsumoto, Shingo, Nakanishi, Rine, Watanabe, Ippei, Aikawa, Hiroto, Noike, Ryota, Yabe, Takayuki, Okubo, Ryo, Fujino, Tadashi, Amano, Hideo, Toda, Mikihito, Ikeda, Takanori

“…Background:Heart rate (HR) is a useful predictor of cardiovascular disease, especially in acute coronary syndrome (ACS). However, it is unclear whether there…”
Get full text

Molecular Hydrogen Alleviates Cellular Senescence in Endothelial Cells by Hara, Fumihiko, Tatebe, Junko, Watanabe, Ippei, Yamazaki, Junichi, Ikeda, Takanori, Morita, Toshisuke

“…Background:Substantial evidence indicates that molecular hydrogen (H2) has beneficial vascular effects because of its antioxidant and/or anti-inflammatory…”
Get full text

Frailty and coronary plaque characteristics on optical coherence tomography by Amano, Hideo, Noike, Ryota, Yabe, Takayuki, Watanabe, Ippei, Okubo, Ryo, Koizumi, Masayuki, Toda, Mikihito, Ikeda, Takanori

“…The relationship between frailty and plaque characteristics is unclear and was investigated by optical coherence tomography (OCT) in this study. One hundred…”
Get full text

Aryl Hydrocarbon Receptor Mediates Indoxyl Sulfate-Induced Cellular Senescence in Human Umbilical Vein Endothelial Cells by Koizumi, Masayuki, Tatebe, Junko, Watanabe, Ippei, Yamazaki, Junichi, Ikeda, Takanori, Morita, Toshisuke

“…Aim: Vascular senescence, which is accelerated in individuals with chronic kidney disease (CKD), contributes to the development of cardio-renal syndrome, and…”
Get full text

Activation of Aryl Hydrocarbon Receptor Mediates Indoxyl Sulfate-Induced Monocyte Chemoattractant Protein-1 Expression in Human Umbilical Vein Endothelial Cells by Watanabe, Ippei, Tatebe, Junko, Namba, Shunji, Koizumi, Masayuki, Yamazaki, Junichi, Morita, Toshisuke

“…Background: Indoxyl sulfate (IS) is a uremic toxin that causes renal injury, but little is known about its adverse effects on the cardiovascular system. The…”
Get full text

Association between coronary artery calcium score on non-contrast chest computed tomography and all-cause mortality among patients with congestive heart failure by Ota, Kyoko, Nakanishi, Rine, Hashimoto, Hidenobu, Okamura, Yuriko, Watanabe, Ippei, Yabe, Takayuki, Okubo, Ryo, Ikeda, Takanori

“…Coronary artery calcium (CAC) score is a robust prognostic tool to predict cardiac events. Although patients with congestive heart failure (CHF) occasionally…”
Get full text

D-sorbitol can keep the viscosity of dispersive ophthalmic viscosurgical device at room temperature for long term by Nogami, Eiji, Watanabe, Ippei, Hoshi, Hirotaka, Kasahara, Masakazu, Honda, Naoto, Sato, Miwako, Suzuki, Kiyoshi

“…The combination of 3% sodium hyaluronate (HA) and 4% sodium chondroitin sulfate (CS) is used as a dispersive ophthalmic viscosurgical device (OVD) during…”
Get full text

Effect of contrast media on the enzyme activity of condoliase: In vitro assessment by Watanabe, Ippei, Shirogane, Taiichi, Matsuyama, Yukihiro, Chiba, Kazuhiro

“…Background Condoliase has been used in Japan to treat patients with lumbar disc herniation by its injection into the nucleus pulposus. The injection of…”
Get full text

Plaque characteristics and slow flow during percutaneous coronary intervention of irregular protrusion by optical coherence tomography by Amano, Hideo, Noike, Ryota, Saito, Daiga, Yabe, Takayuki, Watanabe, Ippei, Okubo, Ryo, Koizumi, Masayuki, Toda, Mikihito, Ikeda, Takanori

“…Irregular protrusion on optical coherence tomography (OCT) is associated with clinical events and target lesion revascularization. We investigated clinical and…”
Get full text

A Clinical Association between an Increasing Renal Resistive Index and the Atherosclerotic Burden in Patients with a Preserved Renal Function by Watanabe, Ippei, Shintani, Yodo, Terada, Shigenori, Fujii, Takahiro, Kiuchi, Shunsuke, Nakanishi, Rine, Katayanagi, Tomoyuki, Kawasaki, Muneyasu, Tokuhiro, Keiichi, Ohsawa, Hidefumi, Ikeda, Takanori

“…Objective A positive correlation is observed between the progression of renal impairment and the increasing risk of cardiovascular disease. Our aim was to…”
Get full text

Comparing the effects of milrinone and olprinone in patients with congestive heart failure by Dobashi, Shintaro, Watanabe, Ippei, Nakanishi, Rine, Hisatake, Shinji, Kiuchi, Shunsuke, Kabuki, Takayuki, Oka, Takashi, Fujii, Takahiro, Ikeda, Takanori

“…Phosphodiesterase-3 (PDE3) inhibitors are widely used among patients with congestive heart failure (CHF). However, no studies have compared the cardiovascular…”
Get full text