Search Results - "Ip, Margot M."

Conjugated linoleic acid-induced apoptosis in mouse mammary tumor cells is mediated by both G protein coupled receptor-dependent activation of the AMP-activated protein kinase pathway and by oxidative stress by Hsu, Yung-Chung, Ip, Margot M.

“…Conjugated linoleic acid (CLA) has shown chemopreventive activity in several tumorigenesis models, in part through induction of apoptosis. We previously…”
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Tumor necrosis factor deficiency inhibits mammary tumorigenesis and a tumor necrosis factor neutralizing antibody decreases mammary tumor growth in neu/erbB2 transgenic mice by Warren, Mary Ann, Shoemaker, Suzanne F, Shealy, David J, Bshar, Wiam, Ip, Margot M

“…Tumor necrosis factor-α (TNF-α) is a pleiotropic cytokine that is synthesized and secreted by cells of the immune system, as well as by certain epithelia and…”
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Conjugated linoleic acid induces apoptosis of murine mammary tumor cells via Bcl-2 loss by Ou, Lihui, Ip, Clement, Lisafeld, Barbara, Ip, Margot M.

“…Conjugated linoleic acid (CLA) is a powerful anticancer agent in a number of tumor model systems; however, its precise mechanism of action remains elusive…”
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Apoptosis induced by t10,c12-conjugated linoleic acid is mediated by an atypical endoplasmic reticulum stress response by Ou, Lihui, Wu, Yue, Ip, Clement, Meng, Xiaojing, Hsu, Yung-Chun, Ip, Margot M.

“…Conjugated linoleic acid (CLA) inhibits rat mammary carcinogenesis, in part by inducing apoptosis of preneoplastic and neoplastic mammary epithelial cells. The…”
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Conjugated Linoleic Acid Isomers and Mammary Cancer Prevention by Ip, Clement, Dong, Yan, Ip, Margot M, Banni, Sebastiano, Carta, Gianfranca, Angioni, Elisabetta, Murru, Elisabetta, Spada, Simona, Melis, Maria Paola, Saebo, Asgeir

“…There is increasing evidence that individual isomers of conjugated linoleic acid (CLA) may have unique biological or biochemical effects. A primary objective…”
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Functional Significance of MMP-9 in Tumor Necrosis Factor-Induced Proliferation and Branching Morphogenesis of Mammary Epithelial Cells by Lee, Ping-Ping H., Hwang, Jiuan-Jiuan, Murphy, Gillian, Ip, Margot M.

“…Abstract Tissue remodeling is a key process involved in normal mammary gland development, with matrix metalloproteinases (MMPs) playing an important role in…”
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Dietary Intake of Conjugated Linoleic Acids and Risk of Premenopausal and Postmenopausal Breast Cancer, Western New York Exposures and Breast Cancer Study (WEB Study) by MCCANN, Susan E, IP, Clement, IP, Margot M, MCGUIRE, Michelle K, MUTI, Paola, EDGE, Stephen B, TREVISAN, Maurizio, FREUDENHEIM, Jo L

“…Specific fatty acids may have differential effects on breast cancer etiology. Animal studies have suggested that conjugated linoleic acids (CLA), a group of…”
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Activation of the AMP-activated protein kinase–p38 MAP kinase pathway mediates apoptosis induced by conjugated linoleic acid in p53-mutant mouse mammary tumor cells by Hsu, Yung-Chung, Meng, Xiaojing, Ou, Lihui, Ip, Margot M.

“…Conjugated linoleic acid (CLA) inhibits tumorigenesis and tumor growth in most model systems, an effect mediated in part by its pro-apoptotic activity. We…”
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Disruption of estrogen receptor α-p53 interaction in breast tumors: a novel mechanism underlying the anti-tumor effect of radiation therapy by Liu, Wensheng, Ip, Margot M, Podgorsak, Matthew B, Das, Gokul M

“…Inactivation of tumor suppressor p53 is one of the most frequent events in cancer. Unlike many other cancers, however, p53 gene mutations are infrequent in…”
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Changes in ErbB2 (her-2/neu), ErbB3, and ErbB4 during Growth, Differentiation, and Apoptosis of Normal Rat Mammary Epithelial Cells by Darcy, Kathleen M, Zangani, Danilo, Wohlhueter, Ann L, Huang, Ruea-Yea, Vaughan, Mary M, Russell, Joy A, Ip, Margot M

“…Studies were undertaken to examine the natural role of ErbB2, ErbB3, and ErbB4 during the development of normal rat mammary epithelial cells (MECs) in vivo and…”
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Prevention of mammary cancer with conjugated linoleic acid: role of the stroma and the epithelium by Ip, Margot M, Masso-Welch, Patricia A, Ip, Clement

“…Conjugated linoleic acid (CLA), found naturally in dairy products and ruminant meats, refers to isomers of octadecadienoic acid with conjugated double bonds…”
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NFκB1/p50 Is Not Required for Tumor Necrosis Factor-Stimulated Growth of Primary Mammary Epithelial Cells: Implications for NFκB2/p52 and RelB by Zhang, Jiping, Warren, Mary Ann, Shoemaker, Suzanne F, Ip, Margot M

“…Nuclear factor κB (NFκB) plays an important role in mammary gland development and breast cancer. We previously demonstrated that TNF stimulates growth of…”
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Conjugated linoleic acid induces mast cell recruitment during mouse mammary gland stromal remodeling by Russell, Joshua S, McGee, Sibel Oflazoglu, Ip, Margot M, Kuhlmann, Dietrich, Masso-Welch, Patricia A

“…Conjugated linoleic acid (CLA) is a dietary chemopreventive agent that induces apoptosis in the mammary adipose vascular endothelium and decreases mammary…”
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Inhibition of angiogenesis by the cancer chemopreventive agent conjugated linoleic acid by MASSO-WELCH, Patricia A, ZANGANI, Danilo, IP, Clement, VAUGHAN, Mary M, SHOEMAKER, Suzanne, RAMIREZ, Robert A, IP, Margot M

“…Dietary conjugated linoleic acid (CLA) has been shown previously to inhibit rat mammary carcinogenesis. In addition to direct effects on mammary epithelial…”
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Expression, tissue distribution, and cellular localization of the antiapoptotic TIP-B1 protein by Berleth, E S, Masso-Welch, P A, Kazim, L A, Ip, M M, Mihich, E, Ehrke, M J

“…TIP‐B1 is a novel 27‐kDa protein isolated from the cytosol of tumornecrosis factor (TNF)‐stimulated cells. Cells preincubated with TIP‐B1are protected from…”
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Induction of Apoptosis by Conjugated Linoleic Acid in Cultured Mammary Tumor Cells and Premalignant Lesions of the Rat Mammary Gland by IP, C, IP, M. M, LOFTUS, T, SHOEMAKER, S, SHEA-EATON, W

“…Conjugated linoleic acid (CLA) is an effective agent in preventing mammary cancer in rats treated with a carcinogen. The appearance of a tumor mass is the net…”
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The t10,c12 isomer of conjugated linoleic acid stimulates mammary tumorigenesis in transgenic mice over-expressing erbB2 in the mammary epithelium by Ip, Margot M., McGee, Sibel O., Masso-Welch, Patricia A., Ip, Clement, Meng, Xiaojing, Ou, Lihui, Shoemaker, Suzanne F.

“…Conjugated linoleic acid (CLA), a family of isomers of octadecadienoic acid, inhibits rat mammary carcinogenesis, angiogenesis, and lung metastasis from a…”
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MAMMARY FIBROBLASTS STIMULATE GROWTH, ALVEOLAR MORPHOGENESIS, AND FUNCTIONAL DIFFERENTIATION OF NORMAL RAT MAMMARY EPITHELIAL CELLS by DARCY, KATHLEEN M, ZANGANI, DANILO, SHEA-EATON, WENDY, SHOEMAKER, SUZANNE F, LEE, PING-PING H, MEAD, LAWRENCE H, MUDIPALLI, ANURADHA, MEGAN, ROBERTA, IP, MARGOT M

“…Stromal–epithelial interactions play a profound role in regulating normal and tumor development in the mammary gland. The molecular details of these events,…”
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t10,c12-Conjugated linoleic acid stimulates mammary tumor progression in Her2/ErbB2 mice through activation of both proliferative and survival pathways by Meng, Xiaojing, Shoemaker, Suzanne F., McGee, Sibel O., Ip, Margot M.

“…The t10,c12 isomer of conjugated linoleic acid (CLA) inhibits rat mammary carcinogenesis, metastasis from a transplantable mouse mammary tumor and…”
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The Liver-Enriched Inhibitory Protein Isoform of CCAAT/Enhancer-Binding Protein β, But Not Nuclear Factor-κB, Mediates the Transcriptional Inhibition of β-Casein by Tumor Necrosis Factor-α by Zhang, Haitao, Zhang, Haiwei, Lee, Laura, Ip, Margot M

“…TNF-α is a physiological regulator of mammary gland development that stimulates the growth of both normal and malignant mammary epithelial cells in primary…”
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