Search Results - "Ip, Jacque P K"
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Locally coordinated synaptic plasticity of visual cortex neurons in vivo
Published in Science (American Association for the Advancement of Science) (22-06-2018)“…Plasticity of cortical responses in vivo involves activity-dependent changes at synapses, but the manner in which different forms of synaptic plasticity act…”
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2
Rett syndrome: insights into genetic, molecular and circuit mechanisms
Published in Nature reviews. Neuroscience (01-06-2018)“…Rett syndrome (RTT) is a severe neurological disorder caused by mutations in the gene encoding methyl-CpG-binding protein 2 (MeCP2). Almost two decades of…”
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3
Lipocalin 2 in the central nervous system host response to systemic lipopolysaccharide administration
Published in Journal of neuroinflammation (26-09-2011)“…Lipocalin 2 (Lcn2) is a bacteriostatic factor that may also modulate cellular function, however, little is known concerning the expression or role of Lcn2 in…”
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4
The Bacteriostatic Protein Lipocalin 2 Is Induced in the Central Nervous System of Mice with West Nile Virus Encephalitis
Published in Journal of Virology (01-01-2014)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cdk5-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortex
Published in Nature communications (05-09-2014)“…During cerebral cortex development, pyramidal neurons migrate through the intermediate zone and integrate into the cortical plate. These neurons undergo the…”
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6
CRMP2: Functional Roles in Neural Development and Therapeutic Potential in Neurological Diseases
Published in The Neuroscientist (01-12-2014)“…Cytoskeletal restructuring is essential for nearly all cellular processes in the developing brain. After cell fate determination, newborn cortical neurons must…”
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Book Review Journal Article -
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Major Vault Protein, a Candidate Gene in 16p11.2 Microdeletion Syndrome, Is Required for the Homeostatic Regulation of Visual Cortical Plasticity
Published in The Journal of neuroscience (18-04-2018)“…Microdeletion of a region in chromosome 16p11.2 increases susceptibility to autism. Although this region contains exons of 29 genes, disrupting only a small…”
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8
Cdk5-mediated phosphorylation of Axin directs axon formation during cerebral cortex development
Published in The Journal of neuroscience (21-09-2011)“…Axon formation is critical for the establishment of connections between neurons, which is a prerequisite for the development of neural circuitry. Kinases such…”
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9
Cdk5-dependent Mst3 phosphorylation and activity regulate neuronal migration through RhoA inhibition
Published in The Journal of neuroscience (28-05-2014)“…The radial migration of newborn neurons is critical for the lamination of the cerebral cortex. Proper neuronal migration requires precise and rapid…”
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10
Ankyrin repeat-rich membrane spanning protein (kidins220) is required for neurotrophin and ephrin receptor-dependent dendrite development
Published in The Journal of neuroscience (13-06-2012)“…Dendrites are the primary sites on neurons for receiving and integrating inputs from their presynaptic partners. Defects in dendrite development perturb the…”
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11
alpha 2-chimaerin controls neuronal migration and functioning of the cerebral cortex through CRMP-2
Published in Nature neuroscience (01-01-2012)“…Disrupted cortical neuronal migration is associated with epileptic seizures and developmental delay. However, the molecular mechanism by which disruptions of…”
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12
Generation of a homozygous ABCA7-knockout human iPSC line using the CRISPR/Cas9 system
Published in Stem cell research (01-02-2023)“…ABCA7 encodes an ATP-binding cassette transporter, and its loss-of-function variants are associated with Alzheimer’s disease. To investigate the role of ABCA7…”
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13
α2-Chimaerin is essential for neural stem cell homeostasis in mouse adult neurogenesis
Published in Proceedings of the National Academy of Sciences - PNAS (02-07-2019)“…Adult hippocampal neurogenesis involves the lifelong generation of neurons. The process depends on the homeostasis of the production of neurons and maintenance…”
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14
Scapinin-induced Inhibition of Axon Elongation Is Attenuated by Phosphorylation and Translocation to the Cytoplasm
Published in The Journal of biological chemistry (03-06-2011)“…Scapinin is an actin- and PP1-binding protein that is exclusively expressed in the brain; however, its function in neurons has not been investigated. Here we…”
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15
α2-chimaerin controls neuronal migration and functioning of the cerebral cortex through CRMP-2
Published in Nature neuroscience (2012)“…This study reveals a novel function of the Rho GTPase-activating protein called α2-chimerin in cortical development, where acute knockdown of α2-chimerin…”
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16
[alpha]2-chimaerin controls neuronal migration and functioning of the cerebral cortex through CRMP-2
Published in Nature neuroscience (01-01-2012)“…Disrupted cortical neuronal migration is associated with epileptic seizures and developmental delay. However, the molecular mechanism by which disruptions of…”
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