Systemic amyloidosis due to unknown multiple myeloma in small bowel pseudo-obstruction: case report

Amyloidosis is a pathologic diagnosis characterized by extracellular deposition of insoluble protein fibrils in various organs and tissues. There are two main forms of amyloidosis, primary amyloidosis, and secondary amyloidosis. Gastrointestinal involvement is common in both amyloidosis forms. We de...

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Bibliographic Details
Published in:	Clinical management issues Vol. 10; no. 1; pp. 15 - 18
Main Authors:	Caparrotti, Giuseppe, Di Maria, Diego, Iovane, Elia, Martone, Clemente, Graziani, Francesco, De Falco, Giuseppina, Esposito, Daniela, Marotta, Claudio, Papa, Giuseppina, Orabona, Isidoro, Rossetti, Davide Albino, Armiento, Nicola, Ferrara, Gennaro, Pezzella, Pasquale
Format:	Journal Article
Language:	English
Published:	SEEd 31-03-2016
Subjects:	Amyloidosis Congo red stain Hypogammaglobulinemia Myeloma Pseudo-obstruction
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Summary:	Amyloidosis is a pathologic diagnosis characterized by extracellular deposition of insoluble protein fibrils in various organs and tissues. There are two main forms of amyloidosis, primary amyloidosis, and secondary amyloidosis. Gastrointestinal involvement is common in both amyloidosis forms. We describe the case of a 78-year-old woman taken to the operating room for small bowel obstruction, found to have pseudo-obstruction and enteritis. Exploratory laparotomy revealed gastric mass and histological examen showed extensive amyloid deposition consistent with amyloidosis. Hematological evaluation revealed unknown multiple myeloma. This case report and literature data suggest to perform a hematological examination in patients with amyloidosis diagnosis to exclude a multiple myeloma or other plasma cell disorders
ISSN:	1973-4832 2283-3137
DOI:	10.7175/cmi.v10i1.1213