Effect of an analog of vasopressin on the fixation of temporary connections in the intact rat and after destruction of the locus coeruleus

Subcutaneous injection to intact rats and rats with destroyed locus coeruleus of 10 mcg of triglycide-glycinamide-lysinevasopressin (TGDGA-LVP) immediately after elaboration of labyrinth defensive conditioned reflex improves consolidation of temporary connections and raises its resistance to extinct...

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Bibliographic Details
Published in:	Zurnal vyss̆ej nervnoj dejatelnosti imeni I P Pavlova Vol. 37; no. 1; p. 95
Main Authors:	Kruglikov, R I, Orlova, N V, Mats, V N, Sarychev, E I, Iosht, K
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-01-1987
Subjects:	Adrenergic Fibers - drug effects Animals Brain Mapping Conditioning, Classical - drug effects Electroshock Extinction, Psychological - drug effects Light Locus Coeruleus - drug effects Lypressin - analogs & derivatives Lypressin - pharmacology Male Memory - drug effects Neural Pathways - drug effects Rats Telencephalon - drug effects
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Summary:	Subcutaneous injection to intact rats and rats with destroyed locus coeruleus of 10 mcg of triglycide-glycinamide-lysinevasopressin (TGDGA-LVP) immediately after elaboration of labyrinth defensive conditioned reflex improves consolidation of temporary connections and raises its resistance to extinction. Improved consolidation of temporary connection is retained in animals with destroyed locus coeruleus for a shorter time than in intact animals. At the same time according to some characteristics, TGDGA-LVP has a more expressed influence of positive character on animals with destroyed locus coeruleus than on intact rats.
ISSN:	0044-4677