Search Results - "Iordanov, Iordan"

Ruling out pyridine dinucleotides as true TRPM2 channel activators reveals novel direct agonist ADP-ribose-2'-phosphate by Tóth, Balázs, Iordanov, Iordan, Csanády, László

“…Transient receptor potential melastatin 2 (TRPM2), a Ca(2+)-permeable cation channel implicated in postischemic neuronal cell death, leukocyte activation, and…”
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Enzyme activity and selectivity filter stability of ancient TRPM2 channels were simultaneously lost in early vertebrates by Iordanov, Iordan, Tóth, Balázs, Szollosi, Andras, Csanády, László

“…Transient Receptor Potential Melastatin 2 (TRPM2) is a cation channel important for the immune response, insulin secretion, and body temperature regulation. It…”
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Estimating the true stability of the prehydrolytic outward-facing state in an ABC protein by Simon, Márton A, Iordanov, Iordan, Szollosi, Andras, Csanády, László

“…CFTR, the anion channel mutated in cystic fibrosis patients, is a model ABC protein whose ATP-driven conformational cycle is observable at single-molecule…”
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Putative chanzyme activity of TRPM2 cation channel is unrelated to pore gating by Tóth, Balázs, Iordanov, Iordan, Csanády, László

“…Transient receptor potential melastatin 2 (TRPM2) is a Ca ²⁺-permeable cation channel expressed in immune cells of phagocytic lineage, pancreatic β cells, and…”
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The proposed channel-enzyme transient receptor potential melastatin 2 does not possess ADP ribose hydrolase activity by Iordanov, Iordan, Mihályi, Csaba, Tóth, Balázs, Csanády, László

“…Transient Receptor Potential Melastatin 2 (TRPM2) is a Ca(2+)-permeable cation channel essential for immunocyte activation, insulin secretion, and postischemic…”
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DNS Tunneling Detection by Cache-Property-Aware Features by Ishikura, Naotake, Kondo, Daishi, Vassiliades, Vassilis, Iordanov, Iordan, Tode, Hideki

“…Many enterprises are under threat of targeted attacks aiming at data exfiltration. To launch such attacks, in recent years, attackers with their malware have…”
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Structural determinants of protein kinase A essential for CFTR channel activation by Mihályi, Csaba, Iordanov, Iordan, Szollosi, Andras, Csanády, László

“…Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), the anion channel mutated in cystic fibrosis (CF) patients, is activated by the catalytic subunit…”
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Cache-Property-Aware Features for DNS Tunneling Detection by Ishikura, Naotake, Kondo, Daishi, Iordanov, Iordan, Vassiliades, Vassilis, Tode, Hideki

“…A lot of enterprises are under threat of targeted attacks causing data exfiltration. As a means of performing the attacks, attackers and their malware have…”
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Posttranslational modifications of cyclic AMP-dependent protein kinase a affect its binding to the CFTR anion channel by Szollosi, Andras, Mihalyi, Csaba, Iordanov, Iordan, Csanady, Laszlo

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Corrigendum to anomalous singularities of semilinear nonstrictly hyperbolic system by Iordanov, Iordan V.

“…We supply counterexamples to results on the propagation of singularities of the solutions of one-dimensional semilinear weakly hyperbolic systems. The examples…”
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Hunting for the Activating ADPR Binding Site of the nvTRPM2 Channel by Toth, Balazs, Iordanov, Iordan, Csanady, Laszlo

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Selective profiling of N- and C-terminal nucleotide-binding sites in a TRPM2 channel by Tóth, Balázs, Iordanov, Iordan, Csanády, László

“…Transient receptor potential melastatin 2 (TRPM2) is a homotetrameric Ca2+-permeable cation channel important for the immune response, body temperature…”
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The structures of protein kinase A in complex with CFTR: Mechanisms of phosphorylation and noncatalytic activation by Fiedorczuk, Karol, Iordanov, Iordan, Mihályi, Csaba, Szollosi, Andras, Csanády, László, Chen, Jue

“…Protein kinase A (PKA) is a key regulator of cellular functions by selectively phosphorylating numerous substrates, including ion channels, enzymes, and…”
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Simple binding of protein kinase A prior to phosphorylation allows CFTR anion channels to be opened by nucleotides by Mihályi, Csaba, Iordanov, Iordan, Töröcsik, Beáta, Csanády, László

“…The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) anion channel is essential for epithelial salt–water balance. CFTR mutations cause cystic…”
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An Ancient TRPM2 Ortholog is a True Channel-Enzyme, But its Catalytic Activity is Uncoupled from Pore Gating by Toth, Balazs, Iordanov, Iordan, Csanady, Laszlo

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Nudt9H Interactions in the Tetrameric TRPM2 Ion Channel by Iordanov, Iordan, Csanady, Laszlo

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Local and Global Dynamics in Klebsiella pneumoniae Outer Membrane Protein a in Lipid Bilayers Probed at Atomic Resolution by Saurel, Olivier, Iordanov, Iordan, Nars, Guillaume, Demange, Pascal, Le Marchand, Tanguy, Andreas, Loren B, Pintacuda, Guido, Milon, Alain

“…The role of membrane proteins in cellular mechanism strongly depends on their dynamics, and solid-state magic-angle spinning (MAS) nuclear magnetic resonance…”
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Two Classes of Cholesterol Binding Sites for the β2AR Revealed by Thermostability and NMR by Gater, Deborah L., Saurel, Olivier, Iordanov, Iordan, Liu, Wei, Cherezov, Vadim, Milon, Alain

“…Cholesterol binding to G protein-coupled receptors (GPCRs) and modulation of their activities in membranes is a fundamental issue for understanding their…”
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Abolition of mitochondrial substrate‐level phosphorylation by itaconic acid produced by LPS‐induced Irg1 expression in cells of murine macrophage lineage by Németh, Beata, Doczi, Judit, Csete, Daniel, Kacso, Gergely, Ravasz, Dora, Adams, Daniel, Kiss, Gergely, Nagy, Adam M., Horvath, Gergo, Tretter, Laszlo, Mócsai, Attila, Csépáinyi‐Kömi, Roland, Iordanov, Iordan, Adam‐Vizi, Vera, Chinopoulos, Christos

“…ABSTRACT Itaconate is a nonamino organic acid exhibiting antimicrobial effects. It has been recently identified in cells of macrophage lineage as a product of…”
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A novel approach for local abdominal aortic aneurysm growth quantification by Metaxa, Eleni, Iordanov, Iordan, Maravelakis, Emmanuel, Papaharilaou, Yannis

“…Although aneurysm size still remains the most accepted predictor of rupture risk, abdominal aortic aneurysms (AAAs) with maximum diameter smaller than 5 cm may…”
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