Search Results - "Ionuț, Ioana"

An Overview of the Synthesis and Antimicrobial, Antiprotozoal, and Antitumor Activity of Thiazole and Bisthiazole Derivatives by Borcea, Anca-Maria, Ionuț, Ioana, Crișan, Ovidiu, Oniga, Ovidiu

“…Thiazole, a five-membered heteroaromatic ring, is an important scaffold of a large number of synthetic compounds. Its diverse pharmacological activity is…”
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New Thiazolyl-triazole Schiff Bases: Synthesis and Evaluation of the Anti-Candida Potential by Stana, Anca, Enache, Alexandra, Vodnar, Dan Cristian, Nastasă, Cristina, Benedec, Daniela, Ionuț, Ioana, Login, Cezar, Marc, Gabriel, Oniga, Ovidiu, Tiperciuc, Brîndușa

“…In the context of the dangerous phenomenon of fungal resistance to the available therapies, we present here the chemical synthesis of a new series of…”
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Synthesis, In Vivo Anticonvulsant Activity Evaluation and In Silico Studies of Some Quinazolin-4(3H)-One Derivatives by Pele, Raluca, Marc, Gabriel, Mogoșan, Cristina, Apan, Anamaria, Ionuț, Ioana, Tiperciuc, Brîndușa, Moldovan, Cristina, Araniciu, Cătălin, Oniga, Ilioara, Pîrnău, Adrian, Vlase, Laurian, Oniga, Ovidiu

“…Two series, " " and " ", each consisting of nine chemical compounds, with 2,3-disubstituted quinazolin-4(3H)-one scaffold, were synthesized and evaluated for…”
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Novel 2,4-Disubstituted-1,3-Thiazole Derivatives: Synthesis, Anti- Candida Activity Evaluation and Interaction with Bovine Serum Albumine by Pricopie, Andreea-Iulia, Focșan, Monica, Ionuț, Ioana, Marc, Gabriel, Vlase, Laurian, Găină, Luiza-Ioana, Vodnar, Dan C, Elemer, Simon, Barta, Gabriel, Pîrnău, Adrian, Oniga, Ovidiu

“…Herein we report the synthesis of two novel series of 1,3-thiazole derivatives having a lipophilic C4-substituent on account of the increasing need for novel…”
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Design and Synthesis of Novel 1,3-Thiazole and 2-Hydrazinyl-1,3-Thiazole Derivatives as Anti- Candida Agents: In Vitro Antifungal Screening, Molecular Docking Study, and Spectroscopic Investigation of their Binding Interaction with Bovine Serum Albumin by Pricopie, Andreea-Iulia, Ionuț, Ioana, Marc, Gabriel, Arseniu, Anca-Maria, Vlase, Laurian, Grozav, Adriana, Găină, Luiza Ioana, Vodnar, Dan C, Pîrnău, Adrian, Tiperciuc, Brîndușa, Oniga, Ovidiu

“…In the context of there being a limited number of clinically approved drugs for the treatment of sp.-based infections, along with the rapid development of…”
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Discovery of A Novel Series of Quinazoline-Thiazole Hybrids as Potential Antiproliferative and Anti-Angiogenic Agents by Șandor, Alexandru, Fizeșan, Ionel, Ionuț, Ioana, Marc, Gabriel, Moldovan, Cristina, Oniga, Ilioara, Pîrnău, Adrian, Vlase, Laurian, Petru, Andreea-Elena, Macasoi, Ioana, Oniga, Ovidiu

“…Considering the pivotal role of angiogenesis in solid tumor progression, we developed a novel series of quinazoline-thiazole hybrids ( ) as antiproliferative…”
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A Novel Series of Acylhydrazones as Potential Anti- Candida Agents: Design, Synthesis, Biological Evaluation and In Silico Studies by Borcea, Anca-Maria, Marc, Gabriel, Ionuț, Ioana, Vodnar, Dan C, Vlase, Laurian, Gligor, Felicia, Pricopie, Andreea, Pîrnău, Adrian, Tiperciuc, Brîndușa, Oniga, Ovidiu

“…In the context of an increased incidence of invasive fungal diseases, there is an imperative need of new antifungal drugs with improved activity and safety…”
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Antioxidant and Cytotoxic Activity of New Polyphenolic Derivatives of Quinazolin-4(3H)-one: Synthesis and In Vitro Activities Evaluation by Pele, Raluca, Marc, Gabriel, Ionuț, Ioana, Nastasă, Cristina, Fizeșan, Ionel, Pîrnău, Adrian, Vlase, Laurian, Palage, Mariana, Oniga, Smaranda, Oniga, Ovidiu

“…The development of hybrid molecules with significant human therapeutic properties is one of the main approaches of pharmaceutical research. One of the most…”
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Synthesis, Cytotoxicity and Antioxidant Activity Evaluation of Some Thiazolyl-Catechol Compounds by Cornea, Alexandra Cătălina, Marc, Gabriel, Ionuț, Ioana, Moldovan, Cristina, Fizeșan, Ionel, Petru, Andreea-Elena, Creștin, Ionuț-Valentin, Pîrnău, Adrian, Vlase, Laurian, Oniga, Ovidiu

“…A series of thiazolyl-catechol compounds with antioxidant and cytotoxic activities were synthesized by a Hantzsch heterocyclization, using diverse thioamides…”
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Synthesis of New Phenolic Derivatives of Quinazolin-4(3H)-One as Potential Antioxidant Agents-In Vitro Evaluation and Quantum Studies by Pele, Raluca, Marc, Gabriel, Stana, Anca, Ionuț, Ioana, Nastasă, Cristina, Tiperciuc, Brîndușa, Oniga, Ilioara, Pîrnău, Adrian, Vlase, Laurian, Oniga, Ovidiu

“…Considering the important damage caused by the reactive oxygen (ROS) and nitrogen (RNS) species in the human organism, the need for new therapeutic agents,…”
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Stapled Peptides by Late‐Stage C(sp3)−H Activation by Noisier, Anaïs F. M., García, Jesús, Ionuţ, Ioana A., Albericio, Fernando

“…Despite the importance of stapled peptides for drug discovery, only few practical processes to prepare cross‐linked peptides have been described; thus the…”
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Structure-Activity Relationship Studies Based on Quinazoline Derivatives as EGFR Kinase Inhibitors (2017-Present) by Șandor, Alexandru, Ionuț, Ioana, Marc, Gabriel, Oniga, Ilioara, Eniu, Dan, Oniga, Ovidiu

“…The epidermal growth factor receptor (EGFR) plays a critical role in the tumorigenesis of various forms of cancer. Targeting the mutant forms of EGFR has been…”
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Synthesis, lipophilicity and antimicrobial activity evaluation of some new thiazolyl-oxadiazolines by STOICA, CRISTINA IOANA, IONUȚ, IOANA, PÎRNĂU, ADRIAN, POP, CARMEN, ROTAR, ANCUȚA, VLASE, LAURIAN, ONIGA, SMARANDA, ONIGA, OVIDIU

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Antibacterial Evaluation and Virtual Screening of New Thiazolyl-Triazole Schiff Bases as Potential DNA-Gyrase Inhibitors by Nastasă, Cristina, Vodnar, Dan C, Ionuţ, Ioana, Stana, Anca, Benedec, Daniela, Tamaian, Radu, Oniga, Ovidiu, Tiperciuc, Brînduşa

“…The global spread of bacterial resistance to drugs used in therapy requires new potent and safe antimicrobial agents. DNA gyrases represent important targets…”
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An Overview of the Structure-Activity Relationship in Novel Antimicrobial Thiazoles Clubbed with Various Heterocycles (2017-2023) by Ungureanu, Daniel, Tiperciuc, Brîndușa, Nastasă, Cristina, Ionuț, Ioana, Marc, Gabriel, Oniga, Ilioara, Oniga, Ovidiu

“…Antimicrobial resistance is an increasing problem for global public health. One of the strategies to combat this issue is the synthesis of novel antimicrobials…”
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Design, Synthesis and Antifungal Activity Evaluation of New Thiazolin-4-ones as Potential Lanosterol 14α-Demethylase Inhibitors by Stana, Anca, Vodnar, Dan C, Tamaian, Radu, Pîrnău, Adrian, Vlase, Laurian, Ionuț, Ioana, Oniga, Ovidiu, Tiperciuc, Brînduşa

“…Twenty-three thiazolin-4-ones were synthesized starting from phenylthioamide or thiourea derivatives by condensation with α-monochloroacetic acid or ethyl…”
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New anti-inflammatory thiazolyl-carbonyl-thiosemicarbazides and thiazolyl-azoles with antioxidant properties as potential iNOS inhibitors by Tiperciuc, Brînduşa, Pârvu, Alina, Tamaian, Radu, Nastasă, Cristina, Ionuţ, Ioana, Oniga, Ovidiu

“…The objective of this study was to investigate the anti-inflammatory and antioxidant activity of new thiazolyl-carbonyl-thiosemicarbazides and thiazolyl-azole…”
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Lipophilicity Evaluation of Some N 1 -Arylidene-Thiosemicarbazones and 1,3,4-Thiadiazolines with Antimicrobial Activity by Ionuţ, Ioana, Tiperciuc, Brînduşa, Oniga, Ovidiu

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An Insight into Rational Drug Design: The Development of In-House Azole Compounds with Antimicrobial Activity by Ungureanu, Daniel, Oniga, Ovidiu, Moldovan, Cristina, Ionuț, Ioana, Marc, Gabriel, Stana, Anca, Pele, Raluca, Duma, Mihaela, Tiperciuc, Brîndușa

“…Antimicrobial resistance poses a major threat to global health as the number of efficient antimicrobials decreases and the number of resistant pathogens rises…”
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DEVELOPMENT OF NEW 2-METHYL-4-SALICYLAMIDE THIAZOLE DERIVATIVES: SYNTHESIS, ANTIMICROBIAL ACTIVITY EVALUATION, LIPOPHILICITY AND MOLECULAR DOCKING STUDY by POP, BIANCA

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