Search Results - "Ioannis Taitzoglou"
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A mixture of routinely encountered xenobiotics induces both redox adaptations and perturbations in blood and tissues of rats after a long-term low-dose exposure regimen: The time and dose issue
Published in Toxicology letters (15-12-2019)“…[Display omitted] •The effects of long-term low-dose exposure to a chemical mixture on redox biomarkers in rats were evaluated.•The mixture induces…”
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Redox Biomarkers Assessment after Oral Administration of Wine Extract and Grape Stem Extract in Rats and Mice
Published in Molecules (Basel, Switzerland) (01-02-2023)“…Wine and by-products of the winemaking process, such as grape stems, are rich in bioactive polyphenolic compounds that might be beneficial for animal and human…”
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Six months exposure to a real life mixture of 13 chemicals' below individual NOAELs induced non monotonic sex-dependent biochemical and redox status changes in rats
Published in Food and chemical toxicology (01-05-2018)“…This study assessed the potential adverse health effects of long-term low-dose exposure to chemical mixtures simulating complex real-life human exposures. Four…”
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Postoperative Administration of Alpha-tocopherol Enhances Osseointegration of Stainless Steel Implants: An In Vivo Rat Model
Published in Clinical orthopaedics and related research (01-02-2020)“…Alpha-tocopherol, a well-known antioxidative agent, may have a positive effect on bone formation during the remodeling phase of secondary fracture healing…”
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Effects of lifelong exercise and aging on the blood metabolic fingerprint of rats
Published in Biogerontology (Dordrecht) (01-10-2020)“…Regular exercise is an important part of a healthy lifestyle, as it helps maintain a healthy weight and reduces the risk of chronic diseases. We explored the…”
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A lightly roasted coffee extract improves blood and tissue redox status in rats through enhancement of GSH biosynthesis
Published in Food and chemical toxicology (01-03-2019)“…Coffee is a highly consumed beverage with many putative beneficial health effects, however these often come from observational studies. In the current work, a…”
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Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) Containing Rice Bran Oil for Enhanced Fenofibrate Oral Delivery: In Vitro Digestion, Ex Vivo Permeability, and In Vivo Bioavailability Studies
Published in AAPS PharmSciTech (01-08-2020)“…Lipid-based drug delivery systems (LbDDS), such as self-nanoemulsifying drug delivery systems (SNEDDS), constitute a prominent formulation approach for…”
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Effect of crocin on antioxidant gene expression, fibrinolytic parameters, redox status and blood biochemistry in nicotinamide-streptozotocin-induced diabetic rats
Published in Journal of biological research (Thessalonikē, Greece) (02-03-2020)“…Abstract Background Diabetes is regarded as an epidemiological threat for the twenty-first century. Phytochemicals with known pharmaceutical properties have…”
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The Strong Antioxidant Sheep/Goat Whey Protein Protects Against mTOR Overactivation in Rats: A Mode of Action Mimicking Fasting
Published in Antioxidants (23-03-2019)“…Whey protein, a by-product of the cheese industry, can be putatively used as a functional food due to its beneficial health properties. The main objective of…”
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Metabolic Phenotyping Study of Mouse Brain Following Microbiome Disruption by C. difficile Colonization
Published in Metabolites (28-10-2022)“…Clostridioides difficile infection (CDI) is responsible for an increasing number of cases of post-antibiotic diarrhea worldwide, which has high severity and…”
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Silver nanoparticles alter the permeability of sheep pleura and of sheep and human pleural mesothelial cell monolayers
Published in Environmental toxicology and pharmacology (01-03-2017)“…Highlights • AgNPs acutely increase the permeability of sheep pleura in a size dependent manner. • AgNPs reduce the permeability of sheep primary mesothelial…”
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Endosulfan-induced lipid peroxidation in rat brain and its effect on t-PA and PAI-1: ameliorating effect of vitamins C and E
Published in Journal of toxicological sciences (01-08-2011)“…Endosulfan provokes systemic toxicity in mammals and induces reactive oxygen species (ROS) and lipid peroxidation (LPO). The brain is susceptible to LPO and…”
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CCl4 induces tissue-type plasminogen activator in rat brain; protective effects of oregano, rosemary or vitamin E
Published in Food and chemical toxicology (01-11-2013)“…•Wistar rats were on a long-term (6-week) dietary supplementation with oregano, rosemary or vitamin E.•The rats were euthanized 48h after a CCl4…”
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Silver Nanoparticles Alter Cell Adhesion and Proliferation of Sheep Primary Mesothelial Cells
Published in In vivo (Athens) (01-01-2018)“…Human exposure to engineered nanoparticles has been linked to pleural effusion, inflammation and fibrosis. Silver nanoparticles (AgNPs) are widely used in…”
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Effects of Aging, Long-Term and Lifelong Exercise on the Urinary Metabolic Footprint of Rats
Published in Metabolites (25-11-2020)“…Life expectancy has risen in the past decades, resulting in an increase in the number of aged individuals. Exercise remains one of the most cost-effective…”
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Impact of Exercise and Aging on Rat Urine and Blood Metabolome. An LC-MS Based Metabolomics Longitudinal Study
Published in Metabolites (23-02-2017)“…Aging is an inevitable condition leading to health deterioration and death. Regular physical exercise can moderate the metabolic phenotype changes of aging…”
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Antioxidant effect of a polyphenol-rich grape pomace extract on motility, viability and lipid peroxidation of thawed bovine spermatozoa
Published in Journal of biological research (Thessalonikē, Greece) (03-11-2014)“…Grape extracts of the Greek species Vitis vinifera possess potent antioxidant properties in vitro. The freeze/thaw process and the preparation of semen during…”
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Effect of long-term dietary administration of oregano and rosemary on the antioxidant status of rat serum, liver, kidney and heart after carbon tetrachloride-induced oxidative stress
Published in Journal of the science of food and agriculture (01-06-2009)“…BACKGROUND: This study was performed on female Wistar rats allocated to eight groups of six animals each. Groups 1 and 2 were fed the basal diet, groups 3 and…”
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Toxoplasma gondii: Reproductive parameters in experimentally infected male rats
Published in Experimental parasitology (01-03-2009)“…Toxoplasma gondii is a protozoan parasite that is globally widespread and infects man and animals. With the aim of studying the influence of toxoplasmosis on…”
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Attenuation of intestinal ischemia/reperfusion induced liver and lung injury by intraperitoneal administration of (-)-epigallocatechin-3-gallate
Published in Free radical research (01-01-2006)“…The aim of this study was to evaluate the effect of ( - )-epigallocatechin-3-gallate (EGCG), a natural antioxidant, on liver and lungs after warm intestinal…”
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