Search Results - "Ioana Agache"

Endotypes of allergic diseases and asthma: An important step in building blocks for the future of precision medicine by Agache, Ioana, Akdis, Cezmi A.

“…Discoveries from basic science research in the last decade have brought significant progress in knowledge of pathophysiologic processes of allergic diseases,…”
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Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: A randomized clinical trial by Kelsen, Steven G., Agache, Ioana O., Soong, Weily, Israel, Elliot, Chupp, Geoffrey L., Cheung, Dorothy S., Theess, Wiebke, Yang, Xiaoying, Staton, Tracy L., Choy, David F., Fong, Alice, Dash, Ajit, Dolton, Michael, Pappu, Rajita, Brightling, Christopher E.

“…The IL-33/ST2 pathway is linked with asthma susceptibility. Inhaled allergens, pollutants, and respiratory viruses, which trigger asthma exacerbations, induce…”
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The effect of allergy and asthma as a comorbidity on the susceptibility and outcomes of COVID-19 by Gao, Ya-dong, Agache, Ioana, Akdis, Mübeccel, Nadeau, Kari, Klimek, Ludger, Jutel, Marek, Akdis, Cezmi A

“…Abstract The coronavirus disease 2019 (COVID-19) pandemic causes an overwhelming number of hospitalization and deaths with a significant socioeconomic impact…”
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Increased serum IL-17 is an independent risk factor for severe asthma by Agache, Ioana, Ciobanu, Cristina, Agache, Costel, Anghel, Mariana

“…Summary Background IL-17 expression was found to be associated with many inflammatory diseases in humans, such as rheumatoid arthritis, asthma, systemic lupus…”
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From phenotypes to endotypes to asthma treatment by Agache, Ioana O

“…PURPOSE OF REVIEWThe current guidelines for asthma diagnosis and management do not recognize that different phenotypes of asthma exist, with significant…”
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Advances and highlights in asthma in 2021 by Agache, Ioana, Eguiluz‐Gracia, Ibon, Cojanu, Catalina, Laculiceanu, Alexandru, Giacco, Stefano, Zemelka‐Wiacek, Magdalena, Kosowska, Anna, Akdis, Cezmi A., Jutel, Marek

“…Last year brought a significant advance in asthma management, unyielding to the pressure of the pandemics. Novel key findings in asthma pathogenesis focus on…”
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EAACI statement on the diagnosis, management and prevention of severe allergic reactions to COVID‐19 vaccines by Sokolowska, Milena, Eiwegger, Thomas, Ollert, Markus, Torres, Maria J., Barber, Domingo, Del Giacco, Stefano, Jutel, Marek, Nadeau, Kari C., Palomares, Oscar, Rabin, Ronald L., Riggioni, Carmen, Vieths, Stefan, Agache, Ioana, Shamji, Mohamed H.

“…The first approved COVID‐19 vaccines include Pfizer/BioNTech BNT162B2, Moderna mRNA‐1273 and AstraZeneca recombinant adenoviral ChAdOx1‐S. Soon after approval,…”
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Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma by Breiteneder, Heimo, Peng, Ya‐Qi, Agache, Ioana, Diamant, Zuzana, Eiwegger, Thomas, Fokkens, Wytske J., Traidl‐Hoffmann, Claudia, Nadeau, Kari, O'Hehir, Robyn E., O'Mahony, Liam, Pfaar, Oliver, Torres, Maria J., Wang, De‐Yun, Zhang, Luo, Akdis, Cezmi A.

“…Modern health care requires a proactive and individualized response to diseases, combining precision diagnosis and personalized treatment. Accordingly, the…”
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Allergen immunotherapy for asthma prevention: A systematic review and meta‐analysis of randomized and non‐randomized controlled studies by Farraia, Mariana, Paciência, Inês, Castro Mendes, Francisca, Cavaleiro Rufo, João, Shamji, Mohamed, Agache, Ioana, Moreira, André

“…Background Allergen immunotherapy (AIT) is a disease‐modifying treatment for IgE‐mediated diseases. Randomized controlled trials (RCTs) support AIT's potential…”
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EAACI Biologicals Guidelines—Recommendations for severe asthma by Agache, Ioana, Akdis, Cezmi A., Akdis, Mubeccel, Canonica, Giorgio Walter, Casale, Thomas, Chivato, Tomas, Corren, Jonathan, Chu, Derek K., Del Giacco, Stefano, Eiwegger, Thomas, Flood, Breda, Firinu, Davide, Gern, James E., Hamelmann, Eckard, Hanania, Nicola, Hernández‐Martín, Irene, Knibb, Rebeca, Mäkelä, Mika, Nair, Parameswaran, O’Mahony, Liam, Papadopoulos, Nikolaos G., Papi, Alberto, Park, Hae‐Sim, Pérez de Llano, Luis, Pfaar, Oliver, Quirce, Santiago, Sastre, Joaquin, Shamji, Mohamed, Schwarze, Jurgen, Palomares, Oscar, Jutel, Marek

“…Severe asthma imposes a significant burden on patients, families and healthcare systems. Management is difficult, due to disease heterogeneity, co‐morbidities,…”
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Diagnosis and management of NSAID‐Exacerbated Respiratory Disease (N‐ERD)—a EAACI position paper by Kowalski, Marek L., Agache, Ioana, Bavbek, Sevim, Bakirtas, Arzu, Blanca, Miguel, Bochenek, Grażyna, Bonini, Matteo, Heffler, Enrico, Klimek, Ludger, Laidlaw, Tanya M., Mullol, Joaquim, Niżankowska‐Mogilnicka, Ewa, Park, Hae‐Sim, Sanak, Marek, Sanchez‐Borges, Mario, Sanchez‐Garcia, Silvia, Scadding, Glenis, Taniguchi, Masami, Torres, Maria J., White, Andrew A., Wardzyńska, Aleksandra

“…NSAID‐exacerbated respiratory disease (N‐ERD) is a chronic eosinophilic, inflammatory disorder of the respiratory tract occurring in patients with asthma…”
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EAACI Guidelines on Allergen Immunotherapy: House dust mite‐driven allergic asthma by Agache, Ioana, Lau, Susanne, Akdis, Cezmi A., Smolinska, Sylwia, Bonini, Matteo, Cavkaytar, Ozlem, Flood, Breda, Gajdanowicz, Pawe, Izuhara, Kenji, Kalayci, Omer, Mosges, Ralph, Palomares, Oscar, Papadopoulos, Nikolaos G., Sokolowska, Milena, Angier, Elisabeth, Fernandez‐Rivas, Montserrat, Pajno, Giovanni, Pfaar, Oliver, Roberts, Graham C., Ryan, Dermot, Sturm, Gunter J., Ree, Ronald, Varga, Eva M., Wijk, Roy Gerth, Yepes‐Nuñez, Juan José, Jutel, Marek

“…Allergen immunotherapy (AIT) has been in use for the treatment of allergic disease for more than 100 years. Asthma treatment relies mainly on corticosteroids…”
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Advances and recent developments in asthma in 2020 by Cevhertas, Lacin, Ogulur, Ismail, Maurer, Debbie J., Burla, Daniel, Ding, Mei, Jansen, Kirstin, Koch, Jana, Liu, Chengyao, Ma, Siyuan, Mitamura, Yasutaka, Peng, Yaqi, Radzikowska, Urszula, Rinaldi, Arturo O., Satitsuksanoa, Pattraporn, Globinska, Anna, Veen, Willem, Sokolowska, Milena, Baerenfaller, Katja, Gao, Ya‐dong, Agache, Ioana, Akdis, Mübeccel, Akdis, Cezmi A.

“…In this review, we discuss recent publications on asthma and review the studies that have reported on the different aspects of the prevalence, risk factors and…”
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Asthma Biomarkers: Do They Bring Precision Medicine Closer to the Clinic? by Agache, Ioana, Rogozea, Liliana

“…Measurement of biomarkers has been incorporated within clinical research of asthma to characterize the population and to associate the disease with…”
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Precision medicine in patients with allergic diseases: Airway diseases and atopic dermatitis—PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology by Muraro, Antonella, MD, Lemanske, Robert F., MD, Hellings, Peter W., MD, Akdis, Cezmi A., MD, Bieber, Thomas, MD, Casale, Thomas B., MD, Jutel, Marek, MD, Ong, Peck Y., MD, Poulsen, Lars K., PhD, Schmid-Grendelmeier, Peter, MD, Simon, Hans-Uwe, MD, Seys, Sven F., PhD, Agache, Ioana, MD

“…In this consensus document we summarize the current knowledge on major asthma, rhinitis, and atopic dermatitis endotypes under the auspices of the PRACTALL…”
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International consensus on allergy immunotherapy by Jutel, Marek, MD, Agache, Ioana, MD, Bonini, Sergio, MD, Burks, A. Wesley, MD, Calderon, Moises, MD, Canonica, Walter, MD, Cox, Linda, MD, Demoly, Pascal, MD, Frew, Antony J., MD, O'Hehir, Robin, MD, Kleine-Tebbe, Jörg, MD, Muraro, Antonella, MD, Lack, Gideon, MD, Larenas, Désirée, MD, Levin, Michael, MD, Nelson, Harald, MD, Pawankar, Ruby, MD, Pfaar, Oliver, MD, van Ree, Ronald, PhD, Sampson, Hugh, MD, Santos, Alexandra F., MD, PhD, Du Toit, George, MD, Werfel, Thomas, MD, Gerth van Wijk, Roy, MD, Zhang, Luo, MD, Akdis, Cezmi A., MD

“…Allergen immunotherapy (AIT) has been used to treat allergic disease since the early 1900s. Despite numerous clinical trials and meta-analyses proving AIT…”
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Emerging concepts and challenges in implementing the exposome paradigm in allergic diseases and asthma: a Practall document by Agache, Ioana, Miller, Rachel, Gern, James E., Hellings, Peter W., Jutel, Marek, Muraro, Antonella, Phipatanakul, Wanda, Quirce, Santiago, Peden, David

“…Exposome research can improve the understanding of the mechanistic connections between exposures and health to help mitigate adverse health outcomes across the…”
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The Concept of One Health for Allergic Diseases and Asthma by Agache, Ioana, Laculiceanu, Alexandru, Spanu, Daniela, Grigorescu, Dan

“…The worldwide prevalence of allergic disease is rising as a result of complex gene-environment interactions that shape the immune system and host response…”
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EAACI position paper on diet diversity in pregnancy, infancy and childhood: Novel concepts and implications for studies in allergy and asthma by Venter, Carina, Greenhawt, Matthew, Meyer, Rosan W., Agostoni, Carlo, Reese, Imke, Toit, George, Feeney, Mary, Maslin, Kate, Nwaru, Bright I., Roduit, Caroline, Untersmayr, Eva, Vlieg‐Boerstra, Berber, Pali‐Schöll, Isabella, Roberts, Graham C., Smith, Peter, Akdis, Cezmi A., Agache, Ioana, Ben‐Adallah, Miriam, Bischoff, Stephan, Frei, Remo, Garn, Holger, Grimshaw, Kate, Hoffmann‐Sommergruber, Karin, Lunjani, Nonhlanhla, Muraro, Antonella, Poulsen, Lars K., Renz, Harald, Sokolowska, Milena, Stanton, Catherine, O'Mahony, Liam

“…To fully understand the role of diet diversity on allergy outcomes and to set standards for conducting research in this field, the European Academy of Allergy…”
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EAACI position paper: Influence of dietary fatty acids on asthma, food allergy, and atopic dermatitis by Venter, Carina, Meyer, Rosan W., Nwaru, Bright I., Roduit, Caroline, Untersmayr, Eva, Adel‐Patient, Karine, Agache, Ioana, Agostoni, Carlo, Akdis, Cezmi A., Bischoff, Stephan C., du Toit, George, Feeney, Mary, Frei, Remo, Garn, Holger, Greenhawt, Matthew, Hoffmann‐Sommergruber, Karin, Lunjani, Nonhlanhla, Maslin, Kate, Mills, Clare, Muraro, Antonella, Pali‐Schöll, Isabella, Poulson, Lars K., Reese, Imke, Renz, Harald, Roberts, Graham C., Smith, Peter, Smolinska, Sylwia, Sokolowska, Milena, Stanton, Catherine, Vlieg‐Boerstra, Berber, O'Mahony, Liam

“…The prevalence of allergic diseases such as allergic rhinitis, asthma, food allergy, and atopic dermatitis has increased dramatically during the last decades,…”
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