Search Results - "Inui, N."

Nivolumab with carboplatin, paclitaxel, and bevacizumab for first-line treatment of advanced nonsquamous non-small-cell lung cancer by Sugawara, S., Lee, J.-S., Kang, J.-H., Kim, H.R., Inui, N., Hida, T., Lee, K.H., Yoshida, T., Tanaka, H., Yang, C.-T., Nishio, M., Ohe, Y., Tamura, T., Yamamoto, N., Yu, C.-J., Akamatsu, H., Namba, Y., Sumiyoshi, N., Nakagawa, K.

“…This international, randomized, double-blind phase III study (ONO-4538-52/TASUKI-52) evaluated nivolumab with bevacizumab and cytotoxic chemotherapy as…”
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Comprehensive assessment of multiple tryptophan metabolites as potential biomarkers for immune checkpoint inhibitors in patients with non-small cell lung cancer by Karayama, M., Masuda, J., Mori, K., Yasui, H., Hozumi, H., Suzuki, Y., Furuhashi, K., Fujisawa, T., Enomoto, N., Nakamura, Y., Inui, N., Suda, T., Maekawa, M., Sugimura, H., Takada, A.

“…Purpose Tryptophan metabolites have immunomodulatory functions, suggesting possible roles in cancer immunity. Methods Plasma tryptophan metabolites were…”
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Chronological Effects of Rifampicin Discontinuation on Cytochrome P450 Activity in Healthy Japanese Volunteers, Using the Cocktail Method by Inui, N, Akamatsu, T, Uchida, S, Tanaka, S, Namiki, N, Karayama, M, Chida, K, Watanabe, H

“…Cytochrome P450 (CYP) 1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A are major factors involved in the metabolism of clinically prescribed drugs. Because the time…”
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Analysis of dynamic sensing of force between a probe and a vibrating sample for purposes of atomic force microscope by Inui, N.

“…Using a perturbation method, we study the influence of the vibration of the sample on the resonance curve of a probe. The obtained resonance curve indicates…”
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Simultaneous LC-MS analysis of plasma concentrations of sildenafil, tadalafil, bosentan, ambrisentan, and macitentan in patients with pulmonary arterial hypertension by Tanaka, S, Uchida, S, Hakamata, A, Miyakawa, S, Odagiri, K, Inui, N, Watanabe, H, Namiki, N

“…Phosphodiesterase-5 (PDE-5) inhibitors and endothelin receptor antagonists (ERAs) are standard therapies for pulmonary arterial hypertension (PAH). The…”
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Respiratory impedance is correlated with airway narrowing in asthma using three‐dimensional computed tomography by Karayama, M., Inui, N., Mori, K., Kono, M., Hozumi, H., Suzuki, Y., Furuhashi, K., Hashimoto, D., Enomoto, N., Fujisawa, T., Nakamura, Y., Watanabe, H., Suda, T.

“…Summary Background Respiratory impedance comprises the resistance and reactance of the respiratory system and can provide detailed information on respiratory…”
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Relationship between contact angle of liquid droplet and light beam position in optoelectrowetting by Inui, N.

“…The contact angle of a liquid droplet on a dielectric-coated electrode can be controlled by changing the voltage between them. In addition, the insertion of a…”
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Interstitial lung diseases associated with amyopathic dermatomyositis by Suda, T, Fujisawa, T, Enomoto, N, Nakamura, Y, Inui, N, Naito, T, Hashimoto, D, Sato, J, Toyoshima, M, Hashizume, H, Chida, K

“…The aim of the present study was to clarify the clinical characteristics and prognosis of patients with interstitial lung disease (ILD) associated with…”
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Dynamic changes in the perceived posture of the hand during ischaemic anaesthesia of the arm by Inui, N., Walsh, L. D., Taylor, J. L., Gandevia, S. C.

“…Non‐technical summary  Even when the hand is stationary we know its position. This information is needed by the brain to plan movements. If the sensory input…”
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Comparative analysis of overall survival using propensity score between first- and second-generation EGFR-TKI: Real world data of 1354 patients with EGFR mutant NSCLC by Ito, K., Murotani, K., Kubo, A., Kunii, E., Taniguchi, H., Shindo, J., Asada, K., Imaizumi, K., Tanaka, K., Inui, N., Okuno, M., Hataji, O., Hayai, S., Abe, T., Kimura, T., Tsuda, T., Yamaguchi, T., Oya, Y., Yoshida, T., Hida, T.

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Real-world data of EGFR minor mutated NSCLC treated with EGFR-TKI: Comparative analysis including compound mutation and de novo T790M mutation by Tanaka, K., Inui, N., Asada, K., Abe, T., Hataji, O., Hayai, S., Ito, K., Imaizumi, K., Kimura, T., Kubo, A., Kunii, E., Murotani, K., Okuno, M., Oya, Y., Shindoh, J., Taniguchi, H., Tsuda, T., Yamaguchi, T., Hida, T., Suda, T.

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Type-1 polarised dendritic cells are a potent immunogen against Mycobacterium tuberculosis by Satake, Y., Nakamura, Y., Kono, M., Hozumi, H., Nagata, T., Tsujimura, K., Enomoto, N., Fujisawa, T., Inui, N., Fujiyama, T., Tokura, Y., Matsui, T., Yokomura, K., Shirai, M., Hayakawa, H., Suda, T.

“…OBJECTIVE: Application of immunotherapy using dendritic cells (DCs) is considered an effective treatment strategy against persistent Mycobacterium tuberculosis…”
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Immunogenicity of dormancy-related antigens in individuals infected with Mycobacterium tuberculosis in Japan by Hozumi, H., Tsujimura, K., Yamamura, Y., Seto, S., Uchijima, M., Nagata, T., Miwa, S., Hayakawa, H., Fujisawa, T., Hashimoto, D., Inui, N., Suda, T., Chida, K., Koide, Y.

“…SETTING: DosR regulon genes are considered essential for Mycobacterium tuberculosis dormancy, and their products are demonstrated to have immunogenicity in M…”
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Effect of PD-1 inhibitor on exhaled nitric oxide and pulmonary function in non-small cell lung cancer patients with and without COPD by Suzuki, Yuzo, Inui, Naoki, Karayama, Masato, Imokawa, Shiro, Yamada, Takashi, Yokomura, Koushi, Asada, Kazuhiro, Kusagaya, Hideki, Kaida, Yusuke, Matsuda, Hiroyuki, Koshimizu, Naoki, Toyoshima, Mikio, Masuda, Masafumi, Hayakawa, Hiroshi, Hozumi, Hironao, Furuhashi, Kazuki, Enomoto, Noriyuki, Fujisawa, Tomoyuki, Nakamura, Yutaro, Suda, Takafumi

“…Nivolumab, a programmed death 1 (PD-1) immune checkpoint inhibitor, has been shown to improve survival in non-small cell lung cancer (NSCLC). The possible…”
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Clinical features of three-dimensional computed tomography-based radiologic phenotypes of chronic obstructive pulmonary disease by Karayama, Masato, Inui, Naoki, Yasui, Hideki, Kono, Masato, Hozumi, Hironao, Suzuki, Yuzo, Furuhashi, Kazuki, Hashimoto, Dai, Enomoto, Noriyuki, Fujisawa, Tomoyuki, Nakamura, Yutaro, Watanabe, Hiroshi, Suda, Takafumi

“…The diagnosis and severity of chronic obstructive pulmonary disease (COPD) are defined by airflow limitation using spirometry. However, COPD has diverse…”
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The CYP2A64 Allele Is Determinant of S-1 Pharmacokinetics in Japanese Patients With Non-small-cell Lung Cancer by Kaida, Y, Inui, N, Suda, T, Nakamura, H, Watanabe, H, Chida, K

“…S‐1 is an oral fluorouracil anticancer drug that contains the 5‐FU prodrug tegafur. Tegafur has been shown to be converted enzymatically to 5‐FU to exert its…”
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PP176—Comparison of Inhibitory Duration of Grapefruit Juice on Organic Anion-Transporting Polypeptide and CYP3A4 by Tanaka, S, Uchida, S, Miyakawa, S, Inui, N, Takeuchi, K, Watanabe, H, Namiki, N

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Pharmacokinetic and Pharmacodynamic Comparison of Sildenafil‐Bosentan and Sildenafil‐Ambrisentan Combination Therapies for Pulmonary Hypertension by Hakamata, A, Odagiri, K, Miyakawa, S, Irisawa, H, Takeuchi, K, Inui, N, Tanaka, S, Uchida, S, Watanabe, H

“…To elucidate whether the pharmacokinetics (PK) and pharmacodynamics (PD) of sildenafil are influenced differently when it is coadministered with bosentan (S+B)…”
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Expression and function of multidrug resistance protein 1 and multidrug resistance-associated protein 1 in lung dendritic cells from aging mice by Inui, Naoki, Hasegawa, Hirotsugu, Suda, Takafumi, Nakamura, Yutaro, Watanabe, Hiroshi, Chida, Kingo

“…Multidrug resistance protein 1 and multidrug resistance-associated protein 1 are transporters that efflux diverse xenobiotics from cells. We investigated…”
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Effects of indacaterol versus tiotropium on respiratory mechanics assessed by the forced oscillation technique in patients with chronic obstructive pulmonary disease by Inui, Naoki, Matsushima, Sayomi, Kato, Shinpei, Yasui, Hideki, Kono, Masato, Fujisawa, Tomoyuki, Enomoto, Noriyuki, Nakamura, Yutaro, Toyoshima, Mikio, Suda, Takafumi

“…The forced oscillation technique (FOT) can measure respiratory mechanics and has attracted attention in chronic obstructive pulmonary disease (COPD). We aimed…”
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