Search Results - "Inthal, A"
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1
CREBBP HAT domain mutations prevail in relapse cases of high hyperdiploid childhood acute lymphoblastic leukemia
Published in Leukemia (01-08-2012)“…Despite their apparently good prognosis ∼15% of high hyperdiploid (HD) childhood acute lymphoblastic leukemia (ALL) cases relapse. To search for responsible…”
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Journal Article -
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Silencing of ETV6/RUNX1 abrogates PI3K/AKT/mTOR signaling and impairs reconstitution of leukemia in xenografts
Published in Leukemia (01-05-2012)“…The ETV6/RUNX1 ( E/R ) gene fusion is generated by the t(12;21) and found in approximately 25% of childhood B-cell precursor acute lymphoblastic leukemia. In…”
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Journal Article -
3
ETV6 RUNX1 abrogates mitotic checkpoint function and targets its key player MAD2L1
Published in Oncogene (03-06-2010)“…Approximately 25% of childhood B-cell precursor acute lymphoblastic leukemia have an ETV6/RUNX1 (E/R) gene fusion that results from a t(12;21). This genetic…”
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Journal Article -
4
Silencing of ETV6/RUNX1 abrogates P13K/AKT/mTOR signaling and impairs reconstitution of leukemia in xenografts
Published in Leukemia (01-05-2012)“…The ETV6/RUNX1 (E/R) gene fusion is generated by the t(12;21) and found in approximately 25% of childhood B-cell precursor acute lymphoblastic leukemia. In…”
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Journal Article