Search Results - "International journal of radiation biology"

The Warburg effect: essential part of metabolic reprogramming and central contributor to cancer progression by Vaupel, Peter, Schmidberger, Heinz, Mayer, Arnulf

“…In the early 1920s, Warburg published experimental data on the enhanced conversion of glucose to pyruvate (followed by lactate formation) even in the presence…”
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Non-canonical roles of apoptotic and DNA double-strand break repair factors in mediating cellular response to ionizing radiation by Li, Chuan-Yuan

“…To provide an updated summary of recent advances in our understanding of the non-canonical roles of apoptotic and DNA double-strand break repair factors in…”
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Low-dose radiation from CT examination induces DNA double-strand breaks and detectable changes of DNA methylation in peripheral blood cells by Wang, Shuo, Li, Gang, Du, Han, Feng, Jiling

“…Radiation burden from CT examinations increases rapidly with the increased clinical use frequency. Previous studies have disclosed the association between…”
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Assessing the impact of low level laser therapy (LLLT) on biological systems: a review by Mussttaf, Ruwaidah A., Jenkins, David F. L., Jha, Awadhesh N.

“…Purpose: Low level laser therapy (LLLT) in the visible to near infrared spectral band (390-1100 nm) is absorption of laser light at the electronic level,…”
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Mechanisms of inflammatory responses to radiation and normal tissues toxicity: clinical implications by Najafi, Masoud, Motevaseli, Elahe, Shirazi, Alireza, Geraily, Ghazale, Rezaeyan, Abolhasan, Norouzi, Farzad, Rezapoor, Saeed, Abdollahi, Hamid

“…Cancer treatment is one of the most challenging diseases in the present era. Among a few modalities for cancer therapy, radiotherapy plays a pivotal role in…”
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Manganese facilitated cGAS-STING-IFNI pathway activation induced by ionizing radiation in glioma cells by He, Yuping, Yang, Ying, Huang, Wenpeng, Yang, Shuangyu, Xue, Xuefei, Zhu, Kun, Tan, Huiling, Sun, Ting, Yang, Wei

“…After irradiation, double-stranded DNA leaked into the cytoplasm activates the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway,…”
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A review of radiation countermeasures focusing on injury-specific medicinals and regulatory approval status: part I. Radiation sub-syndromes, animal models and FDA-approved countermeasures by Singh, Vijay K., Seed, Thomas M.

“…Purpose: The increasing global risk of nuclear and radiological accidents or attacks has driven renewed research interest in developing medical countermeasures…”
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Glutaminase inhibitor CB-839 increases radiation sensitivity of lung tumor cells and human lung tumor xenografts in mice by Boysen, Gunnar, Jamshidi-Parsian, Azemat, Davis, Mary A., Siegel, Eric R., Simecka, Christine M., Kore, Rajshekhar A., Dings, Ruud P. M., Griffin, Robert J.

“…Purpose: The purpose of this study was to translate our in vitro therapy approach to an in vivo model. Increased glutamine uptake is known to drive cancer cell…”
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Understanding the FLASH effect to unravel the potential of ultra-high dose rate irradiation by Kacem, Houda, Almeida, Aymeric, Cherbuin, Nicolas, Vozenin, Marie-Catherine

“…A reemergence of research implementing radiation delivery at ultra-high dose rates (UHDRs) has triggered intense interest in the radiation sciences and has…”
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Cancer stem cells and radioresistance by Rycaj, Kiera, Tang, Dean G.

“…Abstract Purpose: Radiation therapy has made significant contributions to cancer treatment. However, despite continuous improvements, tumor recurrence and…”
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Radiation countermeasures for hematopoietic acute radiation syndrome: growth factors, cytokines and beyond by Singh, Vijay K., Seed, Thomas M.

“…The intent of this article is to report the status of some of the pharmaceuticals currently in late stage development for possible use for individuals…”
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Effects of ionizing radiation on DNA methylation: from experimental biology to clinical applications by Miousse, Isabelle R., Kutanzi, Kristy R., Koturbash, Igor

“…Purpose: Ionizing radiation (IR) is a ubiquitous environmental stressor with genotoxic and epigenotoxic capabilities. Terrestrial IR, predominantly a…”
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A million persons, a million dreams: a vision for a national center of radiation epidemiology and biology by Boice Jr, John D., Quinn, Brian, Al-Nabulsi, Isaf, Ansari, Armin, Blake, Paul K., Blattnig, Steve R., Caffrey, Emily A., Cohen, Sarah S., Golden, Ashley P., Held, Kathryn D., Jokisch, Derek W., Leggett, Richard W., Mumma, Michael T., Samuels, Caleigh, Till, John E., Tolmachev, Sergei Y., Yoder, R. Craig, Zhou, Joey Y., Dauer, Lawrence T.

“…Epidemiologic studies of radiation-exposed populations form the basis for human safety standards. They also help shape public health policy and evidence-based…”
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Mortality among medical radiation workers in the United States, 1965-2016 by Boice, John D., Cohen, Sarah S., Mumma, Michael T., Howard, Sara C., Yoder, R. Craig, Dauer, Lawrence T.

“…Estimates of radiation risks following prolonged exposures at low doses and low-dose rates are uncertain. Medical radiation workers are a major component of…”
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Low- and moderate-dose non-cancer effects of ionizing radiation in directly exposed individuals, especially circulatory and ocular diseases: a review of the epidemiology by Little, Mark P., Azizova, Tamara V., Hamada, Nobuyuki

“…There are well-known correlations between high and moderate doses (>0.5 Gy) of ionizing radiation exposure and circulatory system damage, also between…”
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Ionizing radiation induces ferroptosis in granulocyte-macrophage hematopoietic progenitor cells of murine bone marrow by Zhang, Xiaohong, Xing, Xueshuang, Liu, Huiwen, Feng, Jundong, Tian, Mengxin, Chang, Shuquan, Liu, Peidang, Zhang, Haiqian

“…Purpose: To study whether radiation-induced bleeding in the bone marrow induced iron accumulation, and subsequently caused ferroptosis in…”
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The Million Person Study, whence it came and why by Boice, John D., Cohen, Sarah S., Mumma, Michael T., Ellis, Elizabeth D.

“…The study of low dose and low-dose rate exposure is of immeasurable value in understanding the possible range of health effects from prolonged exposures to…”
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Mortality among U.S. military participants at eight aboveground nuclear weapons test series by Boice, John D., Cohen, Sarah S., Mumma, Michael T., Chen, Heidi, Golden, Ashley P., Beck, Harold L., Till, John E.

“…Approximately 235,000 military personnel participated at one of 230 U.S. atmospheric nuclear weapons tests from 1945 through 1962. At the Nevada Test Site…”
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Updated mortality analysis of the Mallinckrodt uranium processing workers, 1942-2012 by Golden, Ashley P., Ellis, Elizabeth D., Cohen, Sarah S., Mumma, Michael T., Leggett, Richard W., Wallace, Phillip W., Girardi, David, Watkins, Janice P., Shore, Roy E., Boice, John D.

“…Mallinckrodt Chemical Works (MCW) was the earliest uranium processing facility in the United States, and in 1942 produced the uranium oxide used for the first…”
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Transcriptomics for radiation biodosimetry: progress and challenges by Amundson, Sally A.

“…Transcriptomic-based approaches are being developed to meet the needs for large-scale radiation dose and injury assessment and provide population triage…”
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